(Q36024688)

11 August 2017

Minimal effect of MDR1 and CYP3A5 genetic polymorphisms on the pharmacokinetics of indinavir in HIV-infected patients (English)

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11 August 2017

1 reference

1 reference

Isabelle Poizot-Martin

11

object named as

Isabelle Poizot-Martin

1 reference

11 August 2017

Caroline Solas

1

1 reference

11 August 2017

Nicolas Simon

2

1 reference

11 August 2017

Marie-Pierre Drogoul

3

1 reference

11 August 2017

Sylvie Quaranta

4

1 reference

11 August 2017

Véronique Frixon-Marin

5

1 reference

11 August 2017

Véronique Bourgarel-Rey

6

1 reference

11 August 2017

Corinne Brunet

7

1 reference

11 August 2017

Jean-Albert Gastaut

8

1 reference

11 August 2017

Alain Durand

9

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11 August 2017

Bruno Lacarelle

10

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11 August 2017

language of work or name

English

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publication date

22 May 2007

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British Journal of Clinical Pharmacology

11 August 2017

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11 August 2017

64

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11 August 2017

353-362

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11 August 2017

3

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Genetic variability in CYP3A5 and its possible consequences.

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000655

Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000655

MDR1 genotypes do not influence the absorption of a single oral dose of 1 mg digoxin in healthy white males

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000655

P-Glycoprotein and transporter MRP1 reduce HIV protease inhibitor uptake in CD4 cells: potential for accelerated viral drug resistance?

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000655

P-glycoprotein limits oral availability, brain, and fetal penetration of saquinavir even with high doses of ritonavir

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000655

Assessment of active transport of HIV protease inhibitors in various cell lines and the in vitro blood--brain barrier.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000655

Coadministration of cyclosporine strongly enhances the oral bioavailability of docetaxel

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000655

Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000655

Pharmacokinetics and potential interactions amongst antiretroviral agents used to treat patients with HIV infection

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000655

Assumption testing in population pharmacokinetic models: illustrated with an analysis of moxonidine data from congestive heart failure patients.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000655

The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000655

Protease inhibitors in patients with HIV disease. Clinically important pharmacokinetic considerations

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000655

Pharmacokinetic enhancement of inhibitors of the human immunodeficiency virus protease by coadministration with ritonavir.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000655

Association of the CYP3A5 A6986G (CYP3A5*3) polymorphism with saquinavir pharmacokinetics

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000655

Simple high-performance liquid chromatographic determination of the protease inhibitor indinavir in human plasma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000655

HIV-1 protease inhibitors are substrates for the MDR1 multidrug transporter.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000655

Variability in activity of hepatic CYP3A4 in patients infected with HIV.

11 July 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.02903.X

Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.02903.X

Interaction of anti-HIV protease inhibitors with the multidrug transporter P-glycoprotein (P-gp) in human cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.02903.X

Intestinal metabolism promotes regional differences in apical uptake of indinavir: coupled effect of P-glycoprotein and cytochrome P450 3A on indinavir membrane permeability in rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.02903.X

Identification of functionally variant MDR1 alleles among European Americans and African Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.02903.X

Frequency of C3435T polymorphism of MDR1 gene in African people

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.02903.X

MDR1 polymorphisms G2677T in exon 21 and C3435T in exon 26 fail to affect rhodamine 123 efflux in peripheral blood lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.02903.X

Genetic polymorphisms in MDR1 and CYP3A4 genes in Asians and the influence of MDR1 haplotypes on cyclosporin disposition in heart transplant recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.02903.X

CYP3A5 and MDR1 genetic polymorphisms and cyclosporine pharmacokinetics after renal transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.02903.X

The effect of CYP3A5 and MDR1 (ABCB1) polymorphisms on cyclosporine and tacrolimus dose requirements and trough blood levels in stable renal transplant patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.02903.X

Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.02903.X

Genetic findings and functional studies of human CYP3A5 single nucleotide polymorphisms in different ethnic groups

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.02903.X

Response to antiretroviral treatment in HIV-1-infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.02903.X

High indinavir Cmin is associated with higher toxicity in patients on indinavir-ritonavir 800/100 mg twice-daily regimen

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.02903.X

MDR1 pharmacogenetics: frequency of the C3435T mutation in exon 26 is significantly influenced by ethnicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.02903.X

Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.02903.X

HIV protease inhibitor ritonavir: a more potent inhibitor of P-glycoprotein than the cyclosporine analog SDZ PSC 833.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.02903.X

Induction of P-glycoprotein expression by HIV protease inhibitors in cell culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.02903.X

The effects of the human MDR1 genotype on the expression of duodenal P-glycoprotein and disposition of the probe drug talinolol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.02903.X

C3435T polymorphism in the MDR1 gene affects the enterocyte expression level of CYP3A4 rather than Pgp in recipients of living-donor liver transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.02903.X

An MDR1-3435 variant is associated with higher plasma nelfinavir levels and more rapid virologic response in HIV-1 infected children

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.02903.X

Differential inhibition of cytochrome P450 3A4, 3A5 and 3A7 by five human immunodeficiency virus (HIV) protease inhibitors in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2007.02903.X

Digoxin pharmacokinetics and MDR1 genetic polymorphisms

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2000655

Identification by single-strand conformational polymorphism analysis of known and new mutations of the CYP3A5 gene in a French population

21 October 2018

1 reference

12 December 2020

The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells

1 reference

12 December 2020

Coadministration of oral cyclosporin A enables oral therapy with paclitaxel

1 reference

12 December 2020

Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testes

1 reference

12 December 2020

The genetic determinants of the CYP3A5 polymorphism

1 reference

12 December 2020

Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene

1 reference

12 December 2020

Quantitative determination of MDR1 mRNA expression in peripheral blood lymphocytes: a possible role of genetic polymorphisms in the MDR1 gene

1 reference

12 December 2020

Human MDR1 polymorphism: G2677T/A and C3435T have no effect on MDR1 transport activities

1 reference

12 December 2020

Recent developments in HIV protease inhibitor therapy

1 reference

12 December 2020

10.1111/J.1365-2125.2007.02903.X

Identifiers

DOI

1 reference

11 August 2017

1 reference

11 August 2017

1 reference