(Q36024979)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883147%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

Inhibiting fatty acid amide hydrolase normalizes endotoxin-induced enhanced gastrointestinal motility in mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883147%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

0 references

1 reference

1 reference

13

1 reference

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12 February 2020

Keith A. Sharkey

18

1 reference

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12 February 2020

author name string

M Bashashati

1

1 reference

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12 February 2020

M A Storr

2

1 reference

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12 February 2020

S P Nikas

3

1 reference

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12 February 2020

J T Wood

4

1 reference

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12 February 2020

G Godlewski

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883147%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

J Liu

6

1 reference

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12 February 2020

W Ho

7

1 reference

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12 February 2020

C M Keenan

8

1 reference

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12 February 2020

H Zhang

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883147%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

S O Alapafuja

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883147%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

B F Cravatt

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883147%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

B Lutz

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883147%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

G Kunos

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883147%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

K D Patel

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883147%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

J S Davison

17

1 reference

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12 February 2020

A Makriyannis

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883147%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

language of work or name

English

0 references

publication date

1 March 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883147%20AND%20SRC:MED&resulttype=core&format=json

British Journal of Pharmacology

12 February 2020

published in

1 reference

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12 February 2020

volume

165

1 reference

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12 February 2020

issue

5

1 reference

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12 February 2020

page(s)

1556-1571

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883147%20AND%20SRC:MED&resulttype=core&format=json

Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes

12 February 2020

cites work

1 reference

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Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects

2 October 2017

1 reference

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Bacterial cell products signal to mouse colonic nociceptive dorsal root ganglia neurons

2 October 2017

1 reference

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Cannabinoids and the gut: new developments and emerging concepts

2 October 2017

1 reference

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Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions

2 October 2017

1 reference

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FAAH and MAGL inhibitors: therapeutic opportunities from regulating endocannabinoid levels

2 October 2017

1 reference

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Involvement of cannabinoid-1 and cannabinoid-2 receptors in septic ileus

2 October 2017

1 reference

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Ulcerative colitis induces changes on the expression of the endocannabinoid system in the human colonic tissue

2 October 2017

1 reference

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The endocannabinoid system: its general strategy of action, tools for its pharmacological manipulation and potential therapeutic exploitation

2 October 2017

1 reference

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Activation of the cannabinoid 2 receptor (CB2) protects against experimental colitis

2 October 2017

1 reference

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Targeting fatty acid amide hydrolase (FAAH) to treat pain and inflammation

2 October 2017

1 reference

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Cannabinoid receptor activation induces apoptosis through tumor necrosis factor alpha-mediated ceramide de novo synthesis in colon cancer cells

2 October 2017

1 reference

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Cannabinoids and gastrointestinal motility: animal and human studies.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Fatty acid amide hydrolase: a gate-keeper of the endocannabinoid system

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Comprehensive profiling of the human circulating endocannabinoid metabolome: clinical sampling and sample storage parameters

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Cannabinoid CB2 receptors in the enteric nervous system modulate gastrointestinal contractility in lipopolysaccharide-treated rats

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Cannabidiol, extracted from Cannabis sativa, selectively inhibits inflammatory hypermotility in mice

2 October 2017

1 reference

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Enzymatic pathways that regulate endocannabinoid signaling in the nervous system

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Emerging role of cannabinoids in gastrointestinal and liver diseases: basic and clinical aspects.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Cannabinoid CB2 receptors in the gastrointestinal tract: a regulatory system in states of inflammation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

The endocannabinoid system and gut-brain signalling.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

The endogenous cannabinoid anandamide has effects on motivation and anxiety that are revealed by fatty acid amide hydrolase (FAAH) inhibition

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Evaluation of fatty acid amides in the carrageenan-induced paw edema model

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Quantitative method for the profiling of the endocannabinoid metabolome by LC-atmospheric pressure chemical ionization-MS.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Analgesic actions of N-arachidonoyl-serotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Endocannabinoid metabolomics: a novel liquid chromatography-mass spectrometry reagent for fatty acid analysis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Inhibition of fatty acid amide hydrolase produces analgesia by multiple mechanisms

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Molecular biology of the enzymes that degrade endocannabinoids

2 October 2017

1 reference

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Review article: endocannabinoids and their receptors in the enteric nervous system.

2 October 2017

1 reference

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Differential expression of cannabinoid receptors in the human colon: cannabinoids promote epithelial wound healing

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Nerves, reflexes, and the enteric nervous system: pathogenesis of the irritable bowel syndrome

2 October 2017

1 reference

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Effects of cannabinoid receptor-2 activation on accelerated gastrointestinal transit in lipopolysaccharide-treated rats

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

The endogenous cannabinoid system protects against colonic inflammation

2 October 2017

1 reference

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Lipopolysaccharide induces anandamide synthesis in macrophages via CD14/MAPK/phosphoinositide 3-kinase/NF-kappaB independently of platelet-activating factor

2 October 2017

1 reference

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Fatty acid amide hydrolase: an emerging therapeutic target in the endocannabinoid system

2 October 2017

1 reference

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The enzymatic inactivation of the fatty acid amide class of signaling lipids

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Modulation of anxiety through blockade of anandamide hydrolysis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Inhibitory effect of palmitoylethanolamide on gastrointestinal motility in mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Evidence for both inverse agonism at the cannabinoid CB1 receptor and the lack of an endogenous cannabinoid tone in the rat and guinea-pig isolated ileum myenteric plexus-longitudinal muscle preparation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

The identification of peroxisome proliferator-activated receptor alpha-independent effects of oleoylethanolamide on intestinal transit in mice

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

The role of fatty acid hydrolase gene variants in inflammatory bowel disease

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Targeting endocannabinoid degradation protects against experimental colitis in mice: involvement of CB1 and CB2 receptors

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Effect of cannabidiol on sepsis-induced motility disturbances in mice: involvement of CB receptors and fatty acid amide hydrolase

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Melatonin reverses lipopolysaccharide-induced gastro-intestinal motility disturbances through the inhibition of oxidative stress

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Genetic variation in endocannabinoid metabolism, gastrointestinal motility, and sensation

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Reduced anxiety-like behaviour induced by genetic and pharmacological inhibition of the endocannabinoid-degrading enzyme fatty acid amide hydrolase (FAAH) is mediated by CB1 receptors.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Role for NK(1) and NK(2) receptors in the motor activity in mouse colon.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Fatty acid amide hydrolase controls mouse intestinal motility in vivo

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Cisplatin increases brain 2-arachidonoylglycerol (2-AG) and concomitantly reduces intestinal 2-AG and anandamide levels in the least shrew

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Role of oxidative stress in the pathogenesis of septic ileus in mice

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3'-carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and oleoylethanolamide deactivation.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Characterization of the endocannabinoid system in early human pregnancy

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Anandamide hydrolysis: a new target for anti-anxiety drugs?

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Possible endocannabinoid control of colorectal cancer growth

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

A peripheral mechanism for CB1 cannabinoid receptor-dependent modulation of feeding.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

The endogenous cannabinoid system controls extinction of aversive memories

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Endocannabinoids as physiological regulators of colonic propulsion in mice

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Biphasic alterations in gastrointestinal transit following endotoxaemia in mice

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Lipopolysaccharide downregulates fatty acid amide hydrolase expression and increases anandamide levels in human peripheral lymphocytes

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Purification and characterization of an acid amidase selective for N-palmitoylethanolamine, a putative endogenous anti-inflammatory substance

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Differences in the pharmacological properties of rat and chicken brain fatty acid amidohydrolase

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Distribution of anandamide amidohydrolase in rat tissues with special reference to small intestine.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3372737

Fatty acid sulfonyl fluorides inhibit anandamide metabolism and bind to the cannabinoid receptor

23 September 2018

1 reference

12 December 2020

Evidence for a modulatory role of cannabinoids on the excitatory NANC neurotransmission in mouse colon

1 reference

12 December 2020

Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models

1 reference

12 December 2020

Downregulation of cannabinoid receptor 2 (CB2) messenger RNA expression during in vitro stimulation of murine splenocytes with lipopolysaccharide

1 reference

12 December 2020

10.1111/J.1476-5381.2011.01644.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883147%20AND%20SRC:MED&resulttype=core&format=json

release_x4nd5ug6szbrthn32vunxteqem

12 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/x4nd5ug6szbrthn32vunxteqem

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21883147%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference