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Developmental Switch in the Transcriptional Activity of a Long-Range Regulatory Element.
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4561733
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19 February 2020
title
Developmental Switch in the Transcriptional Activity of a Long-Range Regulatory Element
(English)
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4561733
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19 February 2020
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Caroline Conte
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2
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4561733
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19 February 2020
Michel Cogné
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19 February 2020
Ahmed Amine Khamlichi
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19 February 2020
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Fatima-Zohra Braikia
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19 February 2020
Mohamed Moutahir
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3
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19 February 2020
Yves Denizot
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4
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19 February 2020
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20 July 2015
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19 February 2020
published in
Molecular and Cellular Biology
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19 February 2020
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35
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19 February 2020
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19
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19 February 2020
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3370-3380
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19 February 2020
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The distal V(H) gene cluster of the Igh locus contains distinct regulatory elements with Pax5 transcription factor-dependent activity in pro-B cells
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Elements between the IgH variable (V) and diversity (D) clusters influence antisense transcription and lineage-specific V(D)J recombination
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Genomic deletion of the whole IgH 3' regulatory region (hs3a, hs1,2, hs3b, and hs4) dramatically affects class switch recombination and Ig secretion to all isotypes.
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2 October 2017
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2 October 2017
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2 October 2017
The human beta-globin locus control region can silence as well as activate gene expression
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2 October 2017
Chromatin architecture near a potential 3' end of the igh locus involves modular regulation of histone modifications during B-Cell development and in vivo occupancy at CTCF sites
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2 October 2017
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2 October 2017
The V(D)J recombinational and transcriptional activities of the immunoglobulin heavy-chain intronic enhancer can be mediated through distinct protein-binding sites in a transgenic substrate
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2 October 2017
Developmentally controlled and tissue-specific expression of unrearranged VH gene segments
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2 October 2017
RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement
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2 October 2017
Germline deletion of Igh 3' regulatory region elements hs 5, 6, 7 (hs5-7) affects B cell-specific regulation, rearrangement, and insulation of the Igh locus
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11 July 2018
CTCF-binding elements mediate control of V(D)J recombination
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11 July 2018
Sense transcription through the S region is essential for immunoglobulin class switch recombination.
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11 July 2018
Association between the Igk and Igh immunoglobulin loci mediated by the 3' Igk enhancer induces 'decontraction' of the Igh locus in pre-B cells
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11 July 2018
Complete sequence assembly and characterization of the C57BL/6 mouse Ig heavy chain V region
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11 July 2018
Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene
1 reference
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11 July 2018
Quantification of V(D)J recombination by real-time quantitative PCR.
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23 September 2018
Cutting edge: developmental stage-specific recruitment of cohesin to CTCF sites throughout immunoglobulin loci during B lymphocyte development
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4561733
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23 September 2018
Antisense intergenic transcription in V(D)J recombination
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4561733
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23 September 2018
Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4561733
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23 September 2018
Localization of the 3' IgH locus elements that effect long-distance regulation of class switch recombination
1 reference
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12 December 2020
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Regulation of IgH gene assembly: role of the intronic enhancer and 5'DQ52 region in targeting DHJH recombination
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/26195822
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1128/MCB.00509-15
1 reference
stated in
Europe PubMed Central
PMC publication ID
4561733
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26195822%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 February 2020
PMC publication ID
4561733
1 reference
stated in
Europe PubMed Central
PMC publication ID
4561733
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26195822%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 February 2020
PubMed publication ID
26195822
1 reference
stated in
Europe PubMed Central
PMC publication ID
4561733
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26195822%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 February 2020
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