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Metabolic Regulation by Lysine Malonylation, Succinylation, and Glutarylation.
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Europe PubMed Central
PMC publication ID
4563717
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25717114%20AND%20SRC:MED&resulttype=core&format=json
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1 March 2020
review article
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title
Metabolic Regulation by Lysine Malonylation, Succinylation, and Glutarylation
(English)
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PMC publication ID
4563717
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25717114%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
author
Matthew D. Hirschey
series ordinal
1
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Europe PubMed Central
PMC publication ID
4563717
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25717114%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
author name string
Yingming Zhao
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2
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Europe PubMed Central
PMC publication ID
4563717
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25717114%20AND%20SRC:MED&resulttype=core&format=json
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1 March 2020
publication date
25 February 2015
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Europe PubMed Central
PMC publication ID
4563717
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1 March 2020
published in
Molecular & Cellular Proteomics
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PMC publication ID
4563717
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25717114%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
volume
14
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Europe PubMed Central
PMC publication ID
4563717
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25717114%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
issue
9
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Europe PubMed Central
PMC publication ID
4563717
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25717114%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
page(s)
2308-2315
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Europe PubMed Central
PMC publication ID
4563717
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25717114%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
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Proteomic and Biochemical Studies of Lysine Malonylation Suggest Its Malonic Aciduria-associated Regulatory Role in Mitochondrial Function and Fatty Acid Oxidation
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PubMed Central
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Nonenzymatic protein acylation as a carbon stress regulated by sirtuin deacylases
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Lysine glutarylation is a protein posttranslational modification regulated by SIRT5
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Aberrant protein acylation is a common observation in inborn errors of acyl-CoA metabolism
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SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks
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SIRT3: as simple as it seems?
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2 October 2017
Identification of lysine succinylation substrates and the succinylation regulatory enzyme CobB in Escherichia coli
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2 October 2017
Lysine succinylation is a frequently occurring modification in prokaryotes and eukaryotes and extensively overlaps with acetylation
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PubMed Central
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2 October 2017
Widespread and enzyme-independent Nε-acetylation and Nε-succinylation of proteins in the chemical conditions of the mitochondrial matrix
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2 October 2017
SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563717
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2 October 2017
The sirtuin family's role in aging and age-associated pathologies
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Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome
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Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways
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2 October 2017
Mechanistic insights into the regulation of metabolic enzymes by acetylation
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2 October 2017
Metabolic regulation by SIRT3: implications for tumorigenesis
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Lysine succinylation and lysine malonylation in histones.
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2 October 2017
Sirtuins mediate mammalian metabolic responses to nutrient availability
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2 October 2017
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase
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2 October 2017
The first identification of lysine malonylation substrates and its regulatory enzyme
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2 October 2017
SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome
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2 October 2017
Mammalian ACSF3 protein is a malonyl-CoA synthetase that supplies the chain extender units for mitochondrial fatty acid synthesis
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2 October 2017
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization
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2 October 2017
Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction
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2 October 2017
Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity.
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2 October 2017
Identification of lysine succinylation as a new post-translational modification
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2 October 2017
SIRT3 substrate specificity determined by peptide arrays and machine learning
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2 October 2017
Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux
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2 October 2017
Regulation of cellular metabolism by protein lysine acetylation
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2 October 2017
Mitochondrial sirtuins
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2 October 2017
Lysine acetylation targets protein complexes and co-regulates major cellular functions
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2 October 2017
The many roles of histone deacetylases in development and physiology: implications for disease and therapy
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2 October 2017
Lysine acetylation is a highly abundant and evolutionarily conserved modification in Escherichia coli
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2 October 2017
Disorders caused by deficiency of succinate-CoA ligase
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2 October 2017
Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation
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2 October 2017
HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention
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2 October 2017
Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug
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2 October 2017
Substrate and functional diversity of lysine acetylation revealed by a proteomics survey
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2 October 2017
Interactions of GTP with the ATP-grasp domain of GTP-specific succinyl-CoA synthetase
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2 October 2017
AMP kinase and malonyl-CoA: targets for therapy of the metabolic syndrome
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2 October 2017
Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine
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2 October 2017
SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria
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2 October 2017
The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase
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2 October 2017
HDAC6 is a microtubule-associated deacetylase
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2 October 2017
Histone acetyltransferases
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2 October 2017
Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins
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2 October 2017
Structure of the yeast histone acetyltransferase Hat1: insights into substrate specificity and implications for the Gcn5-related N-acetyltransferase superfamily
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2 October 2017
Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity
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2 October 2017
Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
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2 October 2017
A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p
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2 October 2017
Alpha-ketoglutarate dehydrogenase deficiency presenting as congenital lactic acidosis
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2 October 2017
SIRT3 reverses aging-associated degeneration
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11 July 2018
Clinical development of histone deacetylase inhibitor romidepsin
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11 July 2018
Old enzymes, new tricks: sirtuins are NAD(+)-dependent de-acylases
1 reference
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reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4563717
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11 July 2018
Distinct regulation of mitochondrial localization and stability of two human Sirt5 isoforms
1 reference
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PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25717114
retrieved
12 December 2020
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Identifiers
DOI
10.1074/MCP.R114.046664
1 reference
stated in
Europe PubMed Central
PMC publication ID
4563717
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25717114%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
PMC publication ID
4563717
1 reference
stated in
Europe PubMed Central
PMC publication ID
4563717
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25717114%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
PubMed publication ID
25717114
1 reference
stated in
Europe PubMed Central
PMC publication ID
4563717
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25717114%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
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