(Q36263068)

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Proteomic and Biochemical Studies of Lysine Malonylation Suggest Its Malonic Aciduria-associated Regulatory Role in Mitochondrial Function and Fatty Acid Oxidation

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Europe PubMed Central

PMC publication ID

13 August 2017

Proteomic and Biochemical Studies of Lysine Malonylation Suggest Its Malonic Aciduria-associated Regulatory Role in Mitochondrial Function and Fatty Acid Oxidation (English)

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Europe PubMed Central

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13 August 2017

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David B. Lombard

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David B Lombard

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Jason W. Locasale

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Jason W Locasale

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Lunzhi Dai

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Minjia Tan

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Ronald J A Wanders

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Ronald J A Wanders

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13 August 2017

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Gozde Colak

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13 August 2017

Olga Pougovkina

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13 August 2017

Heleen Te Brinke

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13 August 2017

He Huang

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13 August 2017

Zhongyi Cheng

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13 August 2017

Jeongsoon Park

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13 August 2017

Xuelian Wan

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13 August 2017

Xiaojing Liu

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13 August 2017

Wyatt W Yue

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13 August 2017

Vincent C J de Boer

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Yingming Zhao

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28 August 2015

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Molecular & Cellular Proteomics

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13 August 2017

14

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13 August 2017

11

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13 August 2017

3056-3071

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13 August 2017

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9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

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SIRT5 Regulates both Cytosolic and Mitochondrial Protein Malonylation with Glycolysis as a Major Target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4638046

30 September 2017

Sirtuins: guardians of mammalian healthspan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4638046

30 September 2017

Nonenzymatic protein acylation as a carbon stress regulated by sirtuin deacylases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4638046

30 September 2017

Lysine glutarylation is a protein posttranslational modification regulated by SIRT5

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4638046

30 September 2017

Aberrant protein acylation is a common observation in inborn errors of acyl-CoA metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4638046

30 September 2017

Comprehensive measurement of respiratory activity in permeabilized cells using extracellular flux analysis

1 reference

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30 September 2017

SIRT1 and other sirtuins in metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4638046

30 September 2017

Identification of lysine succinylation substrates and the succinylation regulatory enzyme CobB in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4638046

30 September 2017

Lysine succinylation is a frequently occurring modification in prokaryotes and eukaryotes and extensively overlaps with acetylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4638046

30 September 2017

Widespread and enzyme-independent Nε-acetylation and Nε-succinylation of proteins in the chemical conditions of the mitochondrial matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4638046

30 September 2017

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4638046

30 September 2017

Integrated proteomic analysis of post-translational modifications by serial enrichment.

1 reference

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30 September 2017

Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4638046

30 September 2017

Mechanisms of resistance to histone deacetylase inhibitors

1 reference

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30 September 2017

Identification and characterization of an extramitochondrial human 3-hydroxy-3-methylglutaryl-CoA lyase

1 reference

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30 September 2017

Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4638046

30 September 2017

Lysine succinylation and lysine malonylation in histones.

1 reference

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30 September 2017

Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4638046

30 September 2017

Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4638046

30 September 2017

The first identification of lysine malonylation substrates and its regulatory enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4638046

30 September 2017

Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth

1 reference

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30 September 2017

Identification of lysine succinylation as a new post-translational modification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4638046

30 September 2017

Acyl-CoA dehydrogenase 9 is required for the biogenesis of oxidative phosphorylation complex I

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4638046

30 September 2017

A general introduction to the biochemistry of mitochondrial fatty acid β-oxidation

1 reference

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30 September 2017

Regulation of cellular metabolism by protein lysine acetylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4638046

30 September 2017

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis

1 reference

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30 September 2017

Lysine acetylation targets protein complexes and co-regulates major cellular functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4638046

30 September 2017

SIRT5 Deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle

1 reference

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30 September 2017

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

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Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

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30 September 2017

STRING 8--a global view on proteins and their functional interactions in 630 organisms

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A mitochondrial protein compendium elucidates complex I disease biology

1 reference

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30 September 2017

Malonyl-CoA, a key signaling molecule in mammalian cells

1 reference

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30 September 2017

Disorders caused by deficiency of succinate-CoA ligase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4638046

30 September 2017

Hypothalamic malonyl-coenzyme A and the control of energy balance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4638046

30 September 2017

Structural basis for substrate fatty acyl chain specificity: crystal structure of human very-long-chain acyl-CoA dehydrogenase

1 reference

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30 September 2017

Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4638046

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1 reference

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30 September 2017

Fatal malonyl CoA decarboxylase deficiency due to maternal uniparental isodisomy of the telomeric end of chromosome 16

1 reference

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30 September 2017

C-terminal end and aminoacid Lys48 in HMG-CoA lyase are involved in substrate binding and enzyme activity

1 reference

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1 reference

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30 September 2017

Substrate and functional diversity of lysine acetylation revealed by a proteomics survey

1 reference

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Brain abnormalities in a case of malonyl-CoA decarboxylase deficiency

1 reference

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Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins

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Acetyl-CoA carboxylase 2 mutant mice are protected against obesity and diabetes induced by high-fat/high-carbohydrate diets

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Histone acetyltransferases

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30 September 2017

The molecular basis of malonyl-CoA decarboxylase deficiency.

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30 September 2017

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22 September 2018

Malonyl CoA: A promising target for the treatment of cardiac disease.

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22 September 2018

Clinical, enzymatic and molecular characterization of nine new patients with malonyl-coenzyme A decarboxylase deficiency.

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22 September 2018

Impaired mitochondrial fatty acid oxidative flux in fibroblasts from a patient with malonyl-CoA decarboxylase deficiency

1 reference

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1 reference

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1 reference

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21 January 2018

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10.1074/MCP.M115.048850

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13 August 2017

release_pibudjckq5fmnlig3whkfqvv2m

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24 November 2022

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Europe PubMed Central

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13 August 2017

PubMed publication ID

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Europe PubMed Central

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13 August 2017

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