(Q36060423)

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The Thai phase III trial (RV144) vaccine regimen induces T cell responses that preferentially target epitopes within the V2 region of HIV-1 envelope

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scholarly article

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Europe PubMed Central

PMC publication ID

11 August 2017

The Thai phase III trial (RV144) vaccine regimen induces T cell responses that preferentially target epitopes within the V2 region of HIV-1 envelope (English)

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Europe PubMed Central

PMC publication ID

11 August 2017

phase III clinical trial

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13

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Nelson L Michael

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11 August 2017

Jeffrey R Currier

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Jeffrey R Currier

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11 August 2017

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Jerome H Kim

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Supachai Rerks-Ngarm

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Supachai Rerks-Ngarm

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Mary A Marovich

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Mary Marovich

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Doris Thelian

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11 August 2017

Sorachai Nitayaphan

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Sorachai Nitayaphan

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11 August 2017

Punnee Pitisuttithum

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Punnee Pitisuttithum

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Somsak Chantakulkij

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object named as

Somsak Chantakulkij

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Alexandra Schuetz

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Alexandra Schuetz

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Jaranit Kaewkungwal

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object named as

Jaranit Kaewkungwal

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Silvia Ratto-Kim

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Silvia Ratto-Kim

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Weerawan Chuenarom

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object named as

Weerawan Chuenarom

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author name string

Mark S de Souza

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Bessara Nuntapinit

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Anais Valencia-Micolta

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Robert M Paris

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Bonnie Mathieson

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11 August 2017

Ministry of Public Health–Thai AIDS Vaccine Evaluation Group Collaborators

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11 August 2017

language of work or name

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publication date

23 April 2012

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11 August 2017

Journal of Immunology

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11 August 2017

188

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11 August 2017

10

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11 August 2017

5166-5176

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Europe PubMed Central

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11 August 2017

The genotype of early-transmitting HIV gp120s promotes α (4) β(7)-reactivity, revealing α (4) β(7) +/CD4+ T cells as key targets in mucosal transmission

1 reference

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Cytolytic CD4(+) T cells in viral immunity

1 reference

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1 reference

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Immune responses to HIV vaccines and potential impact on control of acute HIV-1 infection

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Prime-boost immunization with poxvirus or adenovirus vectors as a strategy to develop a protective vaccine for HIV-1.

1 reference

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2 October 2017

Phase III HIV vaccine trial in Thailand: a step toward a protective vaccine for HIV.

1 reference

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Priming immunization with DNA augments immunogenicity of recombinant adenoviral vectors for both HIV-1 specific antibody and T-cell responses

1 reference

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2 October 2017

A phase 1/2 study of a multiclade HIV-1 DNA plasmid prime and recombinant adenovirus serotype 5 boost vaccine in HIV-Uninfected East Africans (RV 172).

1 reference

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The integrin alpha4beta7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1.

1 reference

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Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand

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2 October 2017

HIV-1 envelope protein binds to and signals through integrin α4β7, the gut mucosal homing receptor for peripheral T cells

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Essential role of IL-21 in B cell activation, expansion, and plasma cell generation during CD4+ T cell-B cell collaboration

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Preserved central memory and activated effector memory CD4+ T-cell subsets in human immunodeficiency virus controllers: an ANRS EP36 study

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Human immunodeficiency virus type 1 controllers but not noncontrollers maintain CD4 T cells coexpressing three cytokines

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2 October 2017

Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand

1 reference

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2 October 2017

Phase 1 safety and immunogenicity evaluation of a multiclade HIV-1 candidate vaccine delivered by a replication-defective recombinant adenovirus vector

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Phase 2 study of an HIV-1 canarypox vaccine (vCP1452) alone and in combination with rgp120: negative results fail to trigger a phase 3 correlates trial

1 reference

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Functional signatures in antiviral T-cell immunity for monitoring virus-associated diseases.

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Virus-specific CD4+ T cells: ready for direct attack

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Poxvirus-based vaccine candidates for HIV: two decades of experience with special emphasis on canarypox vectors

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Beyond help: direct effector functions of human immunodeficiency virus type 1-specific CD4(+) T cells.

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Safety and immunogenicity of an HIV subtype B and E prime-boost vaccine combination in HIV-negative Thai adults.

1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22529301

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based on heuristic

inferred from PubMed ID database lookup

1 reference

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inferred from PubMed ID database lookup

HIV/AIDS preventive vaccine 'prime-boost' phase III trial: foundations and initial lessons learned from Thailand

1 reference

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Identification of a novel HIV type 1 CRF01_AE cytotoxic T lymphocyte (CTL) epitope restricted by an HLA-Cw0602 allele and a novel HLA-A0206/peptide restriction

1 reference

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A panel of MHC class I restricted viral peptides for use as a quality control for vaccine trial ELISPOT assays

1 reference

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inferred from PubMed ID database lookup

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1 reference

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inferred from PubMed ID database lookup

Comparison Between Env-Specific T-Cell Epitopic Responses in HIV-1-Uninfected Adults Immunized with Combination of ALVAC-HIV(vCP205) Plus or Minus rgp160MN/LAI-2 and HIV-1-Infected Adults

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.1102756

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

ResearchGate publication ID

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