(Q36061394)

11 August 2017

Structural differences between apoE3 and apoE4 may be useful in developing therapeutic agents for Alzheimer's disease (English)

1 reference

11 August 2017

0 references

1

Carl Frieden

1 reference

11 August 2017

Kanchan Garai

2

1 reference

PMC publication ID

3384159

11 August 2017

language of work or name

English

0 references

publication date

21 May 2012

1 reference

Proceedings of the National Academy of Sciences of the United States of America

11 August 2017

1 reference

11 August 2017

109

1 reference

11 August 2017

23

1 reference

11 August 2017

8913-8918

1 reference

Small molecule structure correctors abolish detrimental effects of apolipoprotein E4 in cultured neurons.

11 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384159

Hydrogen/deuterium exchange and electron-transfer dissociation mass spectrometry determine the interface and dynamics of apolipoprotein E oligomerization

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384159

Topology of human apolipoprotein E3 uniquely regulates its diverse biological functions

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384159

Mass spectrometry-based protein footprinting characterizes the structures of oligomeric apolipoprotein E2, E3, and E4.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384159

Structure-dependent impairment of intracellular apolipoprotein E4 trafficking and its detrimental effects are rescued by small-molecule structure correctors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384159

Apolipoprotein E in Alzheimer's disease and other neurological disorders

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384159

The role of apolipoprotein E in Alzheimer's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384159

Alzheimer's disease genetics current status and future perspectives

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384159

Insight on the molecular envelope of lipid-bound apolipoprotein E from electron paramagnetic resonance spectroscopy.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384159

Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384159

Apolipoprotein E structure: insights into function.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384159

Apolipoprotein E and Alzheimer's disease: the protective effects of ApoE2 and E3.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384159

Interaction of the N-terminal domain of apolipoprotein E4 with heparin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384159

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384159

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384159

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384159

Human apolipoprotein E. Role of arginine 61 in mediating the lipoprotein preferences of the E3 and E4 isoforms

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384159

Three-dimensional structure of the LDL receptor-binding domain of human apolipoprotein E

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384159

Dissociation of apolipoprotein E oligomers to monomer is required for high-affinity binding to phospholipid vesicles

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384159

Molecular basis for the differences in lipid and lipoprotein binding properties of human apolipoproteins E3 and E4.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384159

The association−dissociation behavior of the ApoE proteins: kinetic and equilibrium studies

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384159

Relative efficacies of amyloid beta peptide (A beta) binding proteins in A beta aggregation.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384159

Human apolipoprotein E4 domain interaction. Arginine 61 and glutamic acid 255 interact to direct the preference for very low density lipoproteins

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384159

APOE genotype in cerebrovascular disease and vascular dementia.

27 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1207022109

Apolipoprotein E: structure determines function, from atherosclerosis to Alzheimer's disease to AIDS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1207022109

A monomeric, biologically active, full-length human apolipoprotein E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1207022109

A unified scheme for initiation and conformational adaptation of human apolipoprotein E N-terminal domain upon lipoprotein binding and for receptor binding activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1207022109

The structure of human apolipoprotein E2, E3 and E4 in solution 1. Tertiary and quaternary structure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1207022109

Effect of carboxyl-terminal truncation on structure and lipid interaction of human apolipoprotein E4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1207022109

High ability of apolipoprotein E4 to stabilize amyloid-β peptide oligomers, the pathological entities responsible for Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1207022109

Isoform-specific interactions of human apolipoprotein E to an intermediate conformation of human Alzheimer amyloid-beta peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1207022109

Mapping ApoE/Aβ binding regions to guide inhibitor discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1207022109

Model of biologically active apolipoprotein E bound to dipalmitoylphosphatidylcholine

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1207022109

Apolipoprotein E*dipalmitoylphosphatidylcholine particles are ellipsoidal in solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1207022109

Structural differences between apolipoprotein E3 and E4 as measured by (19)F NMR.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384159

An ApoE-Abeta inhibition complex in Abeta fibril extension

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22615372

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1207022109

1 reference

11 August 2017

0 references

1 reference

PMC publication ID

3384159

11 August 2017

PubMed publication ID

22615372

1 reference

PMC publication ID

3384159