(Q36061535)

11 August 2017

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title

The Ras-MAPK signal transduction pathway, cancer and chromatin remodeling (English)

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11 August 2017

Katherine L Dunn

1

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11 August 2017

Paula S Espino

2

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11 August 2017

Bojan Drobic

3

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11 August 2017

Shihua He

4

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11 August 2017

James R Davie

5

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11 August 2017

publication date

1 February 2005

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Biochemistry and Cell Biology

11 August 2017

published in

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11 August 2017

volume

83

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11 August 2017

issue

1

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11 August 2017

page(s)

1-14

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Evidence for a role of MSK1 in transforming growth factor-beta-mediated responses through p38alpha and Smad signaling pathways

11 August 2017

cites work

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Kirsten ras mutations in patients with colorectal cancer: the multicenter "RASCAL" study

21 January 2018

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MSK1 is required for CREB phosphorylation in response to mitogens in mouse embryonic stem cells

21 January 2018

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Mitogen- and stress-activated protein kinase 1 mediates cAMP response element-binding protein phosphorylation and activation by neurotrophins.

21 January 2018

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MAP kinase/estrogen receptor cross-talk enhances estrogen-mediated signaling and tumor growth but does not confer tamoxifen resistance.

21 January 2018

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21 January 2018

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Mitogen-stimulated phosphorylation of histone H3 is targeted to a small hyperacetylation-sensitive fraction

21 January 2018

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Tyrosine kinase signalling in breast cancer: epidermal growth factor receptor and c-Src interactions in breast cancer

21 January 2018

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ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

21 January 2018

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Move over protein kinase C, you've got company: alternative cellular effectors of diacylglycerol and phorbol esters.

21 January 2018

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Role of mitogen-activated protein kinase cascades in mediating lipopolysaccharide-stimulated induction of cyclooxygenase-2 and IL-1 beta in RAW264 macrophages

21 January 2018

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Oncogenic Ras and its role in tumor cell invasion and metastasis

21 January 2018

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Increased Phosphorylation of Histone H1 in Mouse Fibroblasts Transformed with Oncogenes or Constitutively Active Mitogen-activated Protein Kinase Kinase

21 January 2018

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Histone H1b phosphorylation is dependent upon ongoing transcription and replication in normal and ras-transformed mouse fibroblasts

21 January 2018

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Increased Ser-10 phosphorylation of histone H3 in mitogen-stimulated and oncogene-transformed mouse fibroblasts

21 January 2018

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Histone H1(S)-3 phosphorylation in Ha-ras oncogene-transformed mouse fibroblasts

21 January 2018

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Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention.

21 January 2018

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Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase

21 January 2018

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Synergistic coupling of histone H3 phosphorylation and acetylation in response to epidermal growth factor stimulation

21 January 2018

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MAP kinase-mediated phosphoacetylation of histone H3 and inducible gene regulation

21 January 2018

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Phosphoacetylation of histone H3 on c-fos- and c-jun-associated nucleosomes upon gene activation

21 January 2018

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Light induces chromatin modification in cells of the mammalian circadian clock.

21 January 2018

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Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPK

21 January 2018

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Crosstalk between CARM1 methylation and CBP acetylation on histone H3.

21 January 2018

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Regulation and regulatory parameters of histone modifications

21 January 2018

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Organization of chromatin in cancer cells: role of signalling pathways

21 January 2018

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Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB

21 January 2018

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Ligand-independent coactivation of ERalpha AF-1 by steroid receptor RNA activator (SRA) via MAPK activation

21 January 2018

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Phosphorylation and an ATP-dependent process increase the dynamic exchange of H1 in chromatin

21 January 2018

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A genetic model for colorectal tumorigenesis

21 January 2018

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A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation

21 January 2018

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Aurora-B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation

21 January 2018

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Interactions between estrogen and insulin-like growth factor signaling pathways in human breast tumor cells

21 January 2018

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Molecular mechanisms underlying ErbB2/HER2 action in breast cancer

21 January 2018

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MAPK-regulated transcription: a continuously variable gene switch?

21 January 2018

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Nucleosomal histones of transcriptionally active/competent chromatin preferentially exchange with newly synthesized histones in quiescent chicken erythrocytes

21 January 2018

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Increased histone H1 phosphorylation and relaxed chromatin structure in Rb-deficient fibroblasts

21 January 2018

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Phosphorylation of linker histones regulates ATP-dependent chromatin remodeling enzymes

21 January 2018

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Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors

21 January 2018

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The transcriptional program in the response of human fibroblasts to serum

21 January 2018

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Regulation of the ER81 transcription factor and its coactivators by mitogen- and stress-activated protein kinase 1 (MSK1)

21 January 2018

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Estradiol-induced phosphorylation of serine 118 in the estrogen receptor is independent of p42/p44 mitogen-activated protein kinase

21 January 2018

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Transfection of v-rasH DNA into MCF-7 human breast cancer cells bypasses dependence on estrogen for tumorigenicity

21 January 2018

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Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase

21 January 2018

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Eyes wide shut: protein kinase C isozymes are not the only receptors for the phorbol ester tumor promoters

21 January 2018

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Nucleosome remodeling induced by RNA polymerase II: loss of the H2A/H2B dimer during transcription.

21 January 2018

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c-Ha-rasVal 12 oncogene-transformed NIH-3T3 fibroblasts display more decondensed nucleosomal organization than normal fibroblasts

21 January 2018

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DNA methylation is not involved in the structural alterations of ornithine decarboxylase or total chromatin of c-Ha-rasVal 12 oncogene-transformed NIH-3T3 fibroblasts

21 January 2018

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Gene expression pattern of laser microdissected colonic crypts of adenomas with low grade dysplasia

21 January 2018

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Phosphorylation of histone H3 is functionally linked to retinoic acid receptor beta promoter activation

21 January 2018

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Rapid exchange of histone H1.1 on chromatin in living human cells

21 January 2018

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Role of p38alpha Map kinase in Type I interferon signaling

21 January 2018

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Chromosomal protein HMGN1 modulates histone H3 phosphorylation

21 January 2018

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Phosphorylation of 4E-BP1 is mediated by the p38/MSK1 pathway in response to UVB irradiation

21 January 2018

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MAP kinase mediates growth factor-induced nuclear translocation of estrogen receptor alpha

21 January 2018

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Rapid histone H3 phosphorylation in response to growth factors, phorbol esters, okadaic acid, and protein synthesis inhibitors

21 January 2018

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The ras signaling pathway in mammary tumorigenesis and metastasis.

21 January 2018

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Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter

21 January 2018

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Activation of the Src/p21ras/Erk pathway by progesterone receptor via cross-talk with estrogen receptor

21 January 2018

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Dynamic chromatin remodeling on the HER2 promoter in human breast cancer cells.

21 January 2018

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Mitogen- and stress-activated protein kinase 1 mediates activation of Akt by ultraviolet B irradiation

21 January 2018

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Structure of the nucleosome core particle at 7 Å resolution

21 January 2018

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Chromatin condensation: does histone H1 dephosphorylation play a role?

21 January 2018

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The role of mitogen-activated protein (MAP) kinase in breast cancer

21 January 2018

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Requirement of Rsk-2 for epidermal growth factor-activated phosphorylation of histone H3

21 January 2018

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The kinase MSK1 is required for induction of c-fos by lysophosphatidic acid in mouse embryonic stem cells

21 January 2018

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Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription

21 January 2018

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Activation of JNK1, RSK2, and MSK1 is involved in serine 112 phosphorylation of Bad by ultraviolet B radiation

21 January 2018

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Mutation of serines 104, 106, and 118 inhibits dimerization of the human estrogen receptor in yeast

21 January 2018

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Hyperexpression of mitogen-activated protein kinase in human breast cancer

21 January 2018

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MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14

21 January 2018

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Function of the IGF-I receptor in breast cancer

21 January 2018

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Fibroblasts transformed by combinations of ras, myc and mutant p53 exhibit increased phosphorylation of histone H1 that is independent of metastatic potential

21 January 2018

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The nucleosomal response associated with immediate-early gene induction is mediated via alternative MAP kinase cascades: MSK1 as a potential histone H3/HMG-14 kinase

21 January 2018

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Independent dynamic regulation of histone phosphorylation and acetylation during immediate-early gene induction

21 January 2018

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Distinct stimulus-specific histone modifications at hsp70 chromatin targeted by the transcription factor heat shock factor-1.

21 January 2018

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Different Patterns of Gene Expression in ras-Resistant and ras-Sensitive Cells

21 January 2018

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Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1)

21 January 2018

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Erythropoietin-induced serine 727 phosphorylation of STAT3 in erythroid cells is mediated by a MEK-, ERK-, and MSK1-dependent pathway

21 January 2018

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MSK1 and MSK2 are required for the mitogen- and stress-induced phosphorylation of CREB and ATF1 in fibroblasts

21 January 2018

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Histone H3 variants and modifications on transcribed genes

21 January 2018

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Altered MAP kinase (ERK1,2) regulation in primary cultures of mammary tumor cells: elevated basal activity and sustained response to EGF.

21 January 2018

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Transcription factor accessibility and histone acetylation of the progesterone receptor gene differs between parental MCF-7 cells and a subline that has lost progesterone receptor expression

21 January 2018

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Activation of the MAPK pathway enhances sensitivity of MCF-7 breast cancer cells to the mitogenic effect of estradiol

21 January 2018

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MSK1 and JNKs mediate phosphorylation of STAT3 in UVA-irradiated mouse epidermal JB6 cells.

21 January 2018

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Ultraviolet B-induced phosphorylation of histone H3 at serine 28 is mediated by MSK1.

21 January 2018

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MAP kinases mediate UVB-induced phosphorylation of histone H3 at serine 28.

21 January 2018

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Nuclear structure in cancer cells

21 January 2018

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Chromatin fiber structure: morphology, molecular determinants, structural transitions.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1139/O04-121

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11 August 2017

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