(Q36069070)

12 August 2017

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title

The microbiome and innate immunity (English)

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12 August 2017

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4

Eran Elinav

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12 August 2017

1

Christoph A Thaiss

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12 August 2017

2

Niv Zmora

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12 August 2017

Maayan Levy

3

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12 August 2017

language of work or name

English

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publication date

6 July 2016

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12 August 2017

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12 August 2017

volume

535

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12 August 2017

issue

7610

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12 August 2017

page(s)

65-74

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Commensal anaerobic gut bacteria attenuate inflammation by regulating nuclear-cytoplasmic shuttling of PPAR-gamma and RelA.

12 August 2017

cites work

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12 December 2020

Taking it Personally: Personalized Utilization of the Human Microbiome in Health and Disease

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12 December 2020

Innate immunity and intestinal microbiota in the development of Type 1 diabetes

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12 December 2020

Nonredundant function of soluble LTα3 produced by innate lymphoid cells in intestinal homeostasis

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12 December 2020

Epithelial NEMO links innate immunity to chronic intestinal inflammation

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12 December 2020

RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis

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12 December 2020

Gut dysbiosis is linked to hypertension.

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12 December 2020

Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis.

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12 December 2020

Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis

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12 December 2020

Prokaryotic regulation of epithelial responses by inhibition of IkappaB-alpha ubiquitination.

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12 December 2020

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

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12 December 2020

The DNA Sensor AIM2 Maintains Intestinal Homeostasis via Regulation of Epithelial Antimicrobial Host Defense.

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12 December 2020

Interferon-λ cures persistent murine norovirus infection in the absence of adaptive immunity

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12 December 2020

Crosstalk between Microbiota-Derived Short-Chain Fatty Acids and Intestinal Epithelial HIF Augments Tissue Barrier Function.

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12 December 2020

Innate lymphoid cells regulate intestinal epithelial cell glycosylation

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12 December 2020

Porphyromonas gingivalis manipulates complement and TLR signaling to uncouple bacterial clearance from inflammation and promote dysbiosis

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12 December 2020

Bacterial sensor Nod2 prevents inflammation of the small intestine by restricting the expansion of the commensal Bacteroides vulgatus.

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12 December 2020

Commensal bacteria direct selective cargo sorting to promote symbiosis.

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12 December 2020

Microbiota-dependent crosstalk between macrophages and ILC3 promotes intestinal homeostasis.

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12 December 2020

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

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12 December 2020

Life at the beginning: perturbation of the microbiota by antibiotics in early life and its role in health and disease

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12 December 2020

An enteric virus can replace the beneficial function of commensal bacteria

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12 December 2020

Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis

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12 December 2020

Recognition of gut microbiota by NOD2 is essential for the homeostasis of intestinal intraepithelial lymphocytes

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12 December 2020

Commensal bacteria calibrate the activation threshold of innate antiviral immunity

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12 December 2020

Innate immune receptors: key regulators of metabolic disease progression

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12 December 2020

Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis

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12 December 2020

Lineage Relationship Analysis of RORγt+Innate Lymphoid Cells

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12 December 2020

Richness of human gut microbiome correlates with metabolic markers

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12 December 2020

FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation.

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12 December 2020

Crosstalk between muscularis macrophages and enteric neurons regulates gastrointestinal motility.

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12 December 2020

Diet-induced alterations in gut microflora contribute to lethal pulmonary damage in TLR2/TLR4-deficient mice

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12 December 2020

Gut dysbiosis promotes M2 macrophage polarization and allergic airway inflammation via fungi-induced PGE₂.

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12 December 2020

Bacterial metabolite indole modulates incretin secretion from intestinal enteroendocrine L cells

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12 December 2020

Familial transmission rather than defective innate immunity shapes the distinct intestinal microbiota of TLR-deficient mice.

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12 December 2020

Regulated virulence controls the ability of a pathogen to compete with the gut microbiota.

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12 December 2020

Microbiota-Dependent Sequelae of Acute Infection Compromise Tissue-Specific Immunity

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12 December 2020

Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis

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12 December 2020

Exploring new horizons in microbiome research

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12 December 2020

The cytokine IL-22 promotes pathogen colonization by suppressing related commensal bacteria.

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12 December 2020

Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome.

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12 December 2020

Microbiota from Obese Mice Regulate Hematopoietic Stem Cell Differentiation by Altering the Bone Niche.

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12 December 2020

An obesity-associated gut microbiome with increased capacity for energy harvest

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12 December 2020

Microbial exposure during early life has persistent effects on natural killer T cell function

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12 December 2020

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

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12 December 2020

The maternal microbiota drives early postnatal innate immune development.

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12 December 2020

The interplay between the innate immune system and the microbiota

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12 December 2020

Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice

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12 December 2020

Type 2 diabetes as an inflammatory disease

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12 December 2020

Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria

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12 December 2020

Rapid fucosylation of intestinal epithelium sustains host-commensal symbiosis in sickness

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12 December 2020

Innate Lymphoid Cells Control Early Colonization Resistance against Intestinal Pathogens through ID2-Dependent Regulation of the Microbiota.

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12 December 2020

TLR-independent anti-inflammatory function of intestinal epithelial TRAF6 signalling prevents DSS-induced colitis in mice

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12 December 2020

Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5

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12 December 2020

The microbiota regulates neutrophil homeostasis and host resistance to Escherichia coli K1 sepsis in neonatal mice

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12 December 2020

Dysbiosis in inflammatory bowel diseases: the oxygen hypothesis.

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12 December 2020

The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells.

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12 December 2020

NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis

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12 December 2020

Interleukin-22 alleviates metabolic disorders and restores mucosal immunity in diabetes

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12 December 2020

Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis

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12 December 2020

Microbiota-derived compounds drive steady-state granulopoiesis via MyD88/TICAM signaling

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12 December 2020

Epigenetic control of the host gene by commensal bacteria in large intestinal epithelial cells

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12 December 2020

TLRs in the Gut. IV. Negative regulation of Toll-like receptors and intestinal homeostasis: addition by subtraction

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12 December 2020

Transient inability to manage proteobacteria promotes chronic gut inflammation in TLR5-deficient mice

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12 December 2020

RORgammat and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells

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12 December 2020

Commensal microbes and interferon-λ determine persistence of enteric murine norovirus infection

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12 December 2020

Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4.

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12 December 2020

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis.

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12 December 2020

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

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12 December 2020

Commensal-dendritic-cell interaction specifies a unique protective skin immune signature

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12 December 2020

Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense

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12 December 2020

Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth

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12 December 2020

Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy

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12 December 2020

Viral infection. Prevention and cure of rotavirus infection via TLR5/NLRC4-mediated production of IL-22 and IL-18

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12 December 2020

Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria

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12 December 2020

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

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12 December 2020

Interferon-λ and interleukin 22 act synergistically for the induction of interferon-stimulated genes and control of rotavirus infection

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12 December 2020

Immune Interactions with Pathogenic and Commensal Fungi: A Two-Way Street

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12 December 2020

Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury

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12 December 2020

Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria.

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12 December 2020

The multifaceted role of the intestinal microbiota in colon cancer

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12 December 2020

NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer.

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12 December 2020

Microbiota restricts trafficking of bacteria to mesenteric lymph nodes by CX(3)CR1(hi) cells

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12 December 2020

Commensal bacteria control cancer response to therapy by modulating the tumor microenvironment.

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12 December 2020

A functional role for Nlrp6 in intestinal inflammation and tumorigenesis

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12 December 2020

Neutrophil granulocytes recruited upon translocation of intestinal bacteria enhance graft-versus-host disease via tissue damage.

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12 December 2020

Gut microbiota promote hematopoiesis to control bacterial infection

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12 December 2020

The liver may act as a firewall mediating mutualism between the host and its gut commensal microbiota

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12 December 2020

Modulating the Gut Microbiota Improves Glucose Tolerance, Lipoprotein Profile and Atherosclerotic Plaque Development in ApoE-Deficient Mice

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12 December 2020

The antibacterial lectin RegIIIgamma promotes the spatial segregation of microbiota and host in the intestine

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12 December 2020

An IL-23R/IL-22 Circuit Regulates Epithelial Serum Amyloid A to Promote Local Effector Th17 Responses

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12 December 2020

Interleukin 23 production by intestinal CD103(+)CD11b(+) dendritic cells in response to bacterial flagellin enhances mucosal innate immune defense.

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12 December 2020

Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling.

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12 December 2020

Intestinal microbiota promote enteric virus replication and systemic pathogenesis

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12 December 2020

Commensal bacteria protect against food allergen sensitization

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12 December 2020

NLRC4 expression in intestinal epithelial cells mediates protection against an enteric pathogen.

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12 December 2020

Diversity of the human intestinal microbial flora

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12 December 2020

Host microbiota constantly control maturation and function of microglia in the CNS.

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12 December 2020

Epithelial NAIPs protect against colonic tumorigenesis

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12 December 2020

Homeostasis in intestinal epithelium is orchestrated by the circadian clock and microbiota cues transduced by TLRs

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12 December 2020

Immune tolerance. Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria-specific CD4⁺ T cells

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12 December 2020

NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion

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12 December 2020

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

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12 December 2020

Priming of natural killer cells by nonmucosal mononuclear phagocytes requires instructive signals from commensal microbiota

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12 December 2020

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

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12 December 2020

Commensal bacteria-derived signals regulate basophil hematopoiesis and allergic inflammation

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12 December 2020

TLR5-mediated sensing of gut microbiota is necessary for antibody responses to seasonal influenza vaccination

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12 December 2020

Integration of Innate Immune Signaling

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12 December 2020

Epithelium-intrinsic NAIP/NLRC4 inflammasome drives infected enterocyte expulsion to restrict Salmonella replication in the intestinal mucosa

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12 December 2020

Viral immunity. Transkingdom control of viral infection and immunity in the mammalian intestine

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12 December 2020

Origins and functional specialization of macrophages and of conventional and monocyte-derived dendritic cells in mouse skin

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12 December 2020

The cytosolic bacterial peptidoglycan sensor Nod2 affords stem cell protection and links microbes to gut epithelial regeneration

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12 December 2020

Innate and adaptive immunity cooperate flexibly to maintain host-microbiota mutualism

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12 December 2020

The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition

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12 December 2020

Innate immune signalling at the intestinal epithelium in homeostasis and disease.

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12 December 2020

Nlrp6 regulates intestinal antiviral innate immunity

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12 December 2020

Microbiota regulates immune defense against respiratory tract influenza A virus infection

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12 December 2020

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

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12 December 2020

Site-specific programming of the host epithelial transcriptome by the gut microbiota

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12 December 2020

RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota

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12 December 2020

Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis

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12 December 2020

Molecular analysis of commensal host-microbial relationships in the intestine

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12 December 2020

Microbiota modulate transcription in the intestinal epithelium without remodeling the accessible chromatin landscape

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12 December 2020

Diet and feeding pattern affect the diurnal dynamics of the gut microbiome

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12 December 2020

Mining the human gut microbiota for effector strains that shape the immune system

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12 December 2020

Commensal bacteria modulate cullin-dependent signaling via generation of reactive oxygen species

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12 December 2020

Analysis of gene-environment interactions in postnatal development of the mammalian intestine

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12 December 2020

NLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defense

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12 December 2020

Nlrp3 activation in the intestinal epithelium protects against a mucosal pathogen

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12 December 2020

Neutrophil ageing is regulated by the microbiome

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12 December 2020

Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis

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12 December 2020

A unique homologue of the eukaryotic protein-modifier ubiquitin present in the bacterium Bacteroides fragilis, a predominant resident of the human gastrointestinal tract

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12 December 2020

Metagenomic cross-talk: the regulatory interplay between immunogenomics and the microbiome

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12 December 2020

Genetic and Metabolic Signals during Acute Enteric Bacterial Infection Alter the Microbiota and Drive Progression to Chronic Inflammatory Disease

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12 December 2020

The dynamics of the human infant gut microbiome in development and in progression toward type 1 diabetes

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12 December 2020

Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis

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12 December 2020

Human oral, gut, and plaque microbiota in patients with atherosclerosis

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12 December 2020

RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis.

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12 December 2020

Tuft-cell-derived IL-25 regulates an intestinal ILC2-epithelial response circuit

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12 December 2020

Successful transmission of a retrovirus depends on the commensal microbiota

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12 December 2020

Effects of diurnal variation of gut microbes and high-fat feeding on host circadian clock function and metabolism

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12 December 2020

Gut immune maturation depends on colonization with a host-specific microbiota

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12 December 2020

Nod2 is required for the regulation of commensal microbiota in the intestine

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12 December 2020

Innate lymphoid cell interactions with microbiota: implications for intestinal health and disease

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12 December 2020

Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer

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12 December 2020

Reciprocal gut microbiota transplants from zebrafish and mice to germ-free recipients reveal host habitat selection

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12 December 2020

Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4.

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12 December 2020

Identifiers

DOI

10.1038/NATURE18847

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Dimensions Publication ID

12 August 2017

1027001684

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