(Q36078704)

12 August 2017

Inducible and conditional deletion of extracellular signal-regulated kinase 5 disrupts adult hippocampal neurogenesis (English)

1 reference

12 August 2017

1 reference

Yung-Wei Pan

1

1 reference

12 August 2017

Junhui Zou

2

1 reference

12 August 2017

Wenbin Wang

3

1 reference

12 August 2017

Hiroyuki Sakagami

4

1 reference

12 August 2017

Michael G Garelick

5

1 reference

12 August 2017

Glen Abel

6

1 reference

12 August 2017

Chay T Kuo

7

1 reference

12 August 2017

Daniel R Storm

8

1 reference

12 August 2017

Zhengui Xia

9

1 reference

12 August 2017

language of work or name

English

0 references

publication date

29 May 2012

1 reference

Journal of Biological Chemistry

12 August 2017

1 reference

12 August 2017

287

1 reference

12 August 2017

28

1 reference

12 August 2017

23306-23317

1 reference

describes a project that uses

12 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3390609/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Inhibition of adult neurogenesis by inducible and targeted deletion of ERK5 mitogen-activated protein kinase specifically in adult neurogenic regions impairs contextual fear extinction and remote fear memory

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New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?

2 October 2017

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Inhibition of PI3K-Akt signaling blocks exercise-mediated enhancement of adult neurogenesis and synaptic plasticity in the dentate gyrus

2 October 2017

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DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212

2 October 2017

1 reference

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Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis.

2 October 2017

1 reference

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Neurod1 is essential for the survival and maturation of adult-born neurons

2 October 2017

1 reference

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Signaling in adult neurogenesis.

2 October 2017

1 reference

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Molecular genetic analysis of FGFR1 signalling reveals distinct roles of MAPK and PLCgamma1 activation for self-renewal of adult neural stem cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

ERK5 MAP kinase regulates neurogenin1 during cortical neurogenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Deletion of TrkB in adult progenitors alters newborn neuron integration into hippocampal circuits and increases anxiety-like behavior

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Depletion of central BDNF in mice impedes terminal differentiation of new granule neurons in the adult hippocampus.

2 October 2017

1 reference

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TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Induction of neurogenesis in nonconventional neurogenic regions of the adult central nervous system by niche astrocyte-produced signals

2 October 2017

1 reference

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Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

A critical period for enhanced synaptic plasticity in newly generated neurons of the adult brain

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Synapse formation on neurons born in the adult hippocampus.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Neural stem cell isolation and characterization

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Extracellular signal-regulated kinase (ERK) 5 is necessary and sufficient to specify cortical neuronal fate

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

A neurotrophic model for stress-related mood disorders

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Hippocampal neurogenesis: opposing effects of stress and antidepressant treatment

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

The adult mouse hippocampal progenitor is neurogenic but not a stem cell

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Wnt signalling regulates adult hippocampal neurogenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Adult neurogenesis in the mammalian central nervous system

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Targeted deletion of mek5 causes early embryonic death and defects in the extracellular signal-regulated kinase 5/myocyte enhancer factor 2 cell survival pathway

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Learning enhances the survival of new neurons beyond the time when the hippocampus is required for memory

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Hippocampal brain-derived neurotrophic factor expression following treatment with reboxetine, citalopram, and physical exercise

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Basic helix-loop-helix factors in cortical development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

ERK5 activation of MEF2-mediated gene expression plays a critical role in BDNF-promoted survival of developing but not mature cortical neurons

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Functional neurogenesis in the adult hippocampus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Neurotrophins use the Erk5 pathway to mediate a retrograde survival response.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Differential regulation of mitogen-activated protein kinases ERK1/2 and ERK5 by neurotrophins, neuronal activity, and cAMP in neurons.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Disruption of the type III adenylyl cyclase gene leads to peripheral and behavioral anosmia in transgenic mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Learning enhances adult neurogenesis in the hippocampal formation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Retinoic acid and neurotrophins collaborate to regulate neurogenesis in adult-derived neural stem cell cultures

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

BMK1/ERK5 regulates serum-induced early gene expression through transcription factor MEF2C

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Genetic influence on neurogenesis in the dentate gyrus of adult mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

NeuroD2 and neuroD3: distinct expression patterns and transcriptional activation potentials within the neuroD gene family

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Components of a new human protein kinase signal transduction pathway

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Primary structure of BMK1: a new mammalian map kinase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Isolation of MEK5 and differential expression of alternatively spliced forms

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Birth of projection neurons in the higher vocal center of the canary forebrain before, during, and after song learning

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Enhanced synaptic plasticity in newly generated granule cells of the adult hippocampus.

11 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.344762

Preferential incorporation of adult-generated granule cells into spatial memory networks in the dentate gyrus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.344762

Integration of new neurons into functional neural networks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.344762

Hippocampus-dependent learning promotes survival of new neurons in the dentate gyrus at a specific time during cell maturation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.344762

Brain-derived neurotrophic factor activates ERK5 in cortical neurons via a Rap1-MEKK2 signaling cascade.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.344762

Regulation of neuronal survival by the extracellular signal-regulated protein kinase 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.344762

Differential mRNA distribution of components of the ERK/MAPK signalling cascade in the adult mouse brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.344762

Proliferating neuronal progenitors in the postnatal hippocampus transiently express the proneural gene Ngn2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.344762

Intermediate progenitors in adult hippocampal neurogenesis: Tbr2 expression and coordinate regulation of neuronal output

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.344762

Neurogenin 2 has an essential role in development of the dentate gyrus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.344762

Hedgehog and PI-3 kinase signaling converge on Nmyc1 to promote cell cycle progression in cerebellar neuronal precursors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.344762

Dietary restriction enhances neurotrophin expression and neurogenesis in the hippocampus of adult mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.344762

Brain-derived neurotrophic factor (BDNF) is required for the enhancement of hippocampal neurogenesis following environmental enrichment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.344762

Increased neurogenesis and the ectopic granule cells after intrahippocampal BDNF infusion in adult rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.344762

High precision stereotaxic surgery in mice

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Characterization of a neurotrophin signaling mechanism that mediates neuron survival in a temporally specific pattern.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Neural stem cells from adult hippocampus develop essential properties of functional CNS neurons

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3390609

23 September 2018

Identifiers

DOI

10.1074/JBC.M112.344762

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

22645146

1 reference