(Q36088364)

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The Novel, Nicotinic Alpha7 Receptor Partial Agonist, BMS-933043, Improves Cognition and Sensory Processing in Preclinical Models of Schizophrenia

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scholarly article

1 reference

Europe PubMed Central

12 August 2017

The Novel, Nicotinic Alpha7 Receptor Partial Agonist, BMS-933043, Improves Cognition and Sensory Processing in Preclinical Models of Schizophrenia (English)

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Europe PubMed Central

12 August 2017

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Linda J Bristow

1

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Europe PubMed Central

12 August 2017

Amy E Easton

2

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12 August 2017

Yu-Wen Li

3

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12 August 2017

Digavalli V Sivarao

4

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12 August 2017

Regina Lidge

5

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12 August 2017

Kelli M Jones

6

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12 August 2017

Debra Post-Munson

7

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12 August 2017

Christopher Daly

8

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12 August 2017

Nicholas J Lodge

9

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12 August 2017

Lizbeth Gallagher

10

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12 August 2017

Thaddeus Molski

11

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12 August 2017

Richard Pieschl

12

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12 August 2017

Ping Chen

13

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12 August 2017

Adam Hendricson

14

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12 August 2017

Ryan Westphal

15

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12 August 2017

James Cook

16

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12 August 2017

Christiana Iwuagwu

17

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12 August 2017

Daniel Morgan

18

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12 August 2017

Yulia Benitex

19

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12 August 2017

Dalton King

20

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12 August 2017

John E Macor

21

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12 August 2017

Robert Zaczek

22

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12 August 2017

Richard Olson

23

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12 August 2017

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publication date

28 July 2016

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12 August 2017

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12 August 2017

11

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12 August 2017

7

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12 August 2017

e0159996

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Europe PubMed Central

12 August 2017

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Creative Commons Attribution 4.0 International

28 July 2016

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April 2022 Public Data File from Crossref

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Targeting of α7 Nicotinic Acetylcholine Receptors in the Treatment of Schizophrenia and the Use of Auditory Sensory Gating as a Translational Biomarker

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Normalizing effects of EVP-6124, an α-7 nicotinic partial agonist, on event-related potentials and cognition: a proof of concept, randomized trial in patients with schizophrenia

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Negative modulation of GABAA α5 receptors by RO4938581 attenuates discrete sub-chronic and early postnatal phencyclidine (PCP)-induced cognitive deficits in rats

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RG3487, a novel nicotinic α7 receptor partial agonist, improves cognition and sensorimotor gating in rodents.

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A randomised, double-blind, placebo-controlled trial of tropisetron in patients with schizophrenia

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Role of channel activation in cognitive enhancement mediated by alpha7 nicotinic acetylcholine receptors

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Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system

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TC-5619: an alpha7 neuronal nicotinic receptor-selective agonist that demonstrates efficacy in animal models of the positive and negative symptoms and cognitive dysfunction of schizophrenia

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Spatial and intracellular relationships between the alpha7 nicotinic acetylcholine receptor and the vesicular acetylcholine transporter in the prefrontal cortex of rat and mouse

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Schizophrenia from a neural circuitry perspective: advancing toward rational pharmacological therapies

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alpha7 and non-alpha7 nicotinic acetylcholine receptors modulate dopamine release in vitro and in vivo in the rat prefrontal cortex

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Molecular and cellular mechanisms of action of nicotine in the CNS.

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Alpha7 nicotinic acetylcholine receptor activation ameliorates scopolamine-induced behavioural changes in a modified continuous Y-maze task in mice

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Recent advances in treating cognitive impairment in schizophrenia

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Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties

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[3H]A-585539 [(1S,4S)-2,2-dimethyl-5-(6-phenylpyridazin-3-yl)-5-aza-2-azoniabicyclo[2.2.1]heptane], a novel high-affinity alpha7 neuronal nicotinic receptor agonist: radioligand binding characterization to rat and human brain

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Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways

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Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the novel selective alpha7 nicotinic receptor agonist SSR180711.

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12 December 2020

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10.1371/JOURNAL.PONE.0159996

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Europe PubMed Central

12 August 2017

2016PLoSO..1159996B

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24 November 2022

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12 August 2017

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Europe PubMed Central

12 August 2017

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