(Q36088451)

12 August 2017

1 reference

title

The use of biopharmaceutic classification of drugs in drug discovery and development: current status and future extension (English)

1 reference

12 August 2017

1 reference

Hans Lennernäs

1

1 reference

PubMed ID

15807982

12 August 2017

Bertil Abrahamsson

series ordinal

2

1 reference

12 August 2017

1 March 2005

1 reference

Journal of Pharmacy and Pharmacology

12 August 2017

1 reference

12 August 2017

57

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12 August 2017

273-285

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12 August 2017

3

1 reference

The effects of pharmaceutical excipients on small intestinal transit

12 August 2017

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Predicting the impact of physiological and biochemical processes on oral drug bioavailability

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Differential absorption of amoxicillin from the human small and large intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

The use of formulation technology to assess regional gastrointestinal drug absorption in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Regional transport and metabolism of ropivacaine and its CYP3A4 metabolite PPX in human intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Characterization of jejunal absorption and apical efflux of ropivacaine, lidocaine and bupivacaine in the rat using in situ and in vitro absorption models

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

PAMPA--a drug absorption in vitro model 7. Comparing rat in situ, Caco-2, and PAMPA permeability of fluoroquinolones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

The biopharmaceutics classification system (BCS): class III drugs - better candidates for BA/BE waiver?

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Direct estimation of the in vivo dissolution of spironolactone, in two particle size ranges, using the single-pass perfusion technique (Loc-I-Gut) in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Plasma concentration profiles and antihypertensive effect of conventional and extended-release felodipine tablets

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

The complexities of hepatic drug transport: current knowledge and emerging concepts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Physiochemical and physiological mechanisms for the effects of food on drug absorption: the role of lipids and pH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Biowaiver extension potential to BCS Class III high solubility-low permeability drugs: bridging evidence for metformin immediate-release tablet

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Linear correlation of the fraction of oral dose absorbed of 64 drugs between humans and rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

A scintigraphic study to investigate the potential for altered gut distribution of loperamide from a loperamide-simethicone formulation in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Estimation of absorption parameters from the non-steady-state phase in the rat gut perfusion model

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Transit of pharmaceutical dosage forms through the small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Upper gastrointestinal (GI) pH in young, healthy men and women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Acute effects of drinking grapefruit juice on the pharmacokinetics and dynamics of felodipine--and its potential clinical relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Prediction of intestinal permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Absorption, distribution, metabolism, and excretion of ximelagatran, an oral direct thrombin inhibitor, in rats, dogs, and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Lessons learned from marketed and investigational prodrugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Comparison between permeability coefficients in rat and human jejunum

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Jejunal permeability in humans in vivo and rats in situ: investigation of molecular size selectivity and solvent drag.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

A structure-permeability study of small drug-like molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Drug, meal and formulation interactions influencing drug absorption after oral administration. Clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Clinical pharmacokinetics of candesartan

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Intestinal microflora: metabolism of drugs and carcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Gastrointestinal transit of amoxicillin modified-release tablets and a placebo tablet including pharmacokinetic assessments of amoxicillin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Physiologically-based pharmacokinetic simulation modelling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

The nifedipine gastrointestinal therapeutic system (GITS). Evaluation of pharmaceutical, pharmacokinetic and pharmacological properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

5'-Amino acid esters of antiviral nucleosides, acyclovir, and AZT are absorbed by the intestinal PEPT1 peptide transporter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Nanoparticle engineering processes for enhancing the dissolution rates of poorly water soluble drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Molecular properties of WHO essential drugs and provisional biopharmaceutical classification

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Application of chitin and chitosan derivatives in the pharmaceutical field.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Expandable gastroretentive dosage forms

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Media to simulate the postprandial stomach I. Matching the physicochemical characteristics of standard breakfasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Probing drug solubilization patterns in the gastrointestinal tract after administration of lipid-based delivery systems: a phase diagram approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Forecasting the oral absorption behavior of poorly soluble weak bases using solubility and dissolution studies in biorelevant media

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Predicting the precipitation of poorly soluble weak bases upon entry in the small intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Human jejunal effective permeability and its correlation with preclinical drug absorption models

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Human intestinal permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Intestinal drug absorption and bioavailability: beyond involvement of single transport function

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

The effect of L-leucine on the absorption of levodopa, studied by regional jejunal perfusion in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

The influence of caprate on rectal absorption of phenoxymethylpenicillin: experience from an in-vivo perfusion in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

The effect of amiloride on the in vivo effective permeability of amoxicillin in human jejunum: experience from a regional perfusion technique

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Characterization of fluids from the stomach and proximal jejunum in men and women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Regional intestinal absorption and biliary excretion of fluvastatin in the rat: possible involvement of mrp2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Emerging Trends in Oral Delivery of Peptide and Protein Drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Impact of drug transporter studies on drug discovery and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

In-vitro and in-vivo studies of cefpirom using bile salts as absorption enhancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Real-time quantitative polymerase chain reaction for MDR1, MRP1, MRP2, and CYP3A-mRNA levels in Caco-2 cell lines, human duodenal enterocytes, normal colorectal tissues, and colorectal adenocarcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

The influence of the interdigestive migrating myoelectric complex on the gastric emptying of liquids

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Nanosuspensions: a promising drug delivery strategy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Transport characteristics of fexofenadine in the Caco-2 cell model

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Use of in vitro lipid digestion data to explain the in vivo performance of triglyceride-based oral lipid formulations of poorly water-soluble drugs: studies with halofantrine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Can the USP paddle method be used to represent in-vivo hydrodynamics?

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Cellular and molecular mechanisms of dietary regulation on rat intestinal H+/Peptide transporter PepT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Intestinal solute carriers: an overview of trends and strategies for improving oral drug absorption

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Multiple transport mechanisms involved in the intestinal absorption and first-pass extraction of fexofenadine

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

The effect of ketoconazole on the in vivo intestinal permeability of fexofenadine using a regional perfusion technique

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Prodrugs of purine and pyrimidine analogues for the intestinal di/tri-peptide transporter PepT1: affinity for hPepT1 in Caco-2 cells, drug release in aqueous media and in vitro metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Enhanced permeability of insulin across the rat intestinal membrane by various absorption enhancers: their intestinal mucosal toxicity and absorption-enhancing mechanism of n-lauryl-beta-D-maltopyranoside.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Membrane transport of drugs in different regions of the intestinal tract of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

ADMET in silico modelling: towards prediction paradise?

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Property-based design: optimization of drug absorption and pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Drug uptake systems in liver and kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Biowaiver monographs for immediate release solid oral dosage forms based on biopharmaceutics classification system (BCS) literature data: verapamil hydrochloride, propranolol hydrochloride, and atenolol

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Determination of in vivo absorption, metabolism, and transport of drugs by the human intestinal wall and liver with a novel perfusion technique.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Correlation of human jejunal permeability (in vivo) of drugs with experimentally and theoretically derived parameters. A multivariate data analysis approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Hydrogen bonding descriptors in the prediction of human in vivo intestinal permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Differentiation of absorption and first-pass gut and hepatic metabolism in humans: studies with cyclosporine

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

The "high solubility" definition of the current FDA Guidance on Biopharmaceutical Classification System may be too strict for acidic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Influence of drug release properties of conventional solid dosage forms on the systemic exposure of highly soluble drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

The effect of food on the relative bioavailability of rapidly dissolving immediate-release solid oral products containing highly soluble drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

Permeability classification of representative fluoroquinolones by a cell culture method

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357055263

21 January 2018

Identifiers

DOI

10.1211/0022357055263

1 reference

12 August 2017

1 reference

PubMed ID

15807982