(Q36104645)

12 August 2017

1 reference

title

Multiple roles for MMPs and TIMPs in cerebral ischemia (English)

1 reference

12 August 2017

1 reference

Lee Anna Cunningham

1

1 reference

PubMed ID

15846802

12 August 2017

Monica Wetzel

series ordinal

2

1 reference

PubMed ID

15846802

12 August 2017

Gary A Rosenberg

series ordinal

3

1 reference

12 August 2017

1 June 2005

1 reference

12 August 2017

1 reference

12 August 2017

50

1 reference

12 August 2017

4

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12 August 2017

329-339

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Gene encoding a novel murine tissue inhibitor of metalloproteinases (TIMP), TIMP-3, is expressed in developing mouse epithelia, cartilage, and muscle, and is located on mouse chromosome 10.

12 August 2017

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

Tissue inhibitors of metalloproteinases: evolution, structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

The many faces of metalloproteases: cell growth, invasion, angiogenesis and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

Microvascular basal lamina antigens disappear during cerebral ischemia and reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

Hypoxia-induced vascular endothelial growth factor expression precedes neovascularization after cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

Matrix metalloproteinases and TIMPs are associated with blood-brain barrier opening after reperfusion in rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

Blood-brain barrier disruption and matrix metalloproteinase-9 expression during reperfusion injury: mechanical versus embolic focal ischemia in spontaneously hypertensive rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Cloning of the cDNA encoding human tissue inhibitor of metalloproteinases-3 (TIMP-3) and mapping of the TIMP3 gene to chromosome 22

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

The gene structure of tissue inhibitor of metalloproteinases (TIMP)-3 and its inhibitory activities define the distinct TIMP gene family

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Essential role for ERK mitogen-activated protein kinase in matrix metalloproteinase-9 regulation in rat cortical astrocytes

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Role for matrix metalloproteinase 9 after focal cerebral ischemia: effects of gene knockout and enzyme inhibition with BB-94.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Matrix metalloproteinase 2 gene knockout has no effect on acute brain injury after focal ischemia.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Death receptors: signaling and modulation

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Matrix metalloproteinase-9 (MMP-9) is synthesized in neurons of the human hippocampus and is capable of degrading the amyloid-beta peptide (1-40).

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Metalloproteinase inhibitors: biological actions and therapeutic opportunities.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Structural properties of matrix metalloproteinases

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Activation systems for latent matrix metalloproteinase-2 are upregulated immediately after focal cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Matrix metalloproteinase-1 activates a pertussis toxin-sensitive signaling pathway that stimulates the release of matrix metalloproteinase-9.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Matrix metalloproteinase 1 interacts with neuronal integrins and stimulates dephosphorylation of Akt.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

β-Amyloid induces the production of active, matrix-degrading proteases in cultured rat astrocytes

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Pathobiology of ischaemic stroke: an integrated view

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Matrix metalloproteinases and their endogenous inhibitors in neuronal physiology of the adult brain

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

New functions for the matrix metalloproteinases in cancer progression

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Matrix metalloproteinases as insulin-like growth factor binding protein-degrading proteinases

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

MMPs are IGFBP-degrading proteinases: implications for cell proliferation and tissue growth

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Regulation of insulin-like growth factor (IGF)-I action by matrix metalloproteinase-3 involves selective disruption of IGF-I/IGF-binding protein-3 complexes

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Matrix metalloproteinase inhibition prevents oxidative stress-associated blood-brain barrier disruption after transient focal cerebral ischemia

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Regulation of matrix metalloproteinase expressions in astrocytes, microglia and neurons

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

S-nitrosylation of matrix metalloproteinases: signaling pathway to neuronal cell death

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Cortical spreading depression activates and upregulates MMP-9.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Hemorrhagic transformation and microvascular integrity during focal cerebral ischemia/reperfusion

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Dexamethasone regulation of matrix metalloproteinase expression in CNS vascular endothelium.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Angiogenesis: vascular remodeling of the extracellular matrix involves metalloproteinases

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Matrix metalloproteinases increase very early during experimental focal cerebral ischemia

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Novel processing of beta-amyloid precursor protein catalyzed by membrane type 1 matrix metalloproteinase releases a fragment lacking the inhibitor domain against gelatinase A.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Jekyll-Hyde neurotrophins: the story of proNGF

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

HIV-1 Tat neurotoxicity is prevented by matrix metalloproteinase inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Neuronal activity-dependent increase of net matrix metalloproteinase activity is associated with MMP-9 neurotoxicity after kainate.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Neutrophil infiltration increases matrix metalloproteinase-9 in the ischemic brain after occlusion/reperfusion of the middle cerebral artery in rats.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Matrix metalloproteinase-9 expression in post-hypoxic human brain capillary endothelial cells: H2O2 as a trigger and NF-kappaB as a signal transducer.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Role of angiogenesis in patients with cerebral ischemic stroke

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

The biphasic opening of the blood-brain barrier to proteins following temporary middle cerebral artery occlusion.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Exploitation of astrocytes by glioma cells to facilitate invasiveness: a mechanism involving matrix metalloproteinase-2 and the urokinase-type plasminogen activator-plasmin cascade.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Regulation of cell survival by secreted proneurotrophins

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Role of matrix metalloproteinases in delayed neuronal damage after transient global cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Induction of matrix metalloproteinase-9 (MMP-9) in lipopolysaccharide-stimulated primary astrocytes is mediated by extracellular signal-regulated protein kinase 1/2 (Erk1/2)

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Dynamic changes in cerebral blood flow and angiogenesis after transient focal cerebral ischemia in rats. Evaluation with serial magnetic resonance imaging.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Mechanisms, challenges and opportunities in stroke

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Tissue inhibitors of metalloproteinases and programmed cell death: conundrums, controversies and potential implications.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Therapeutic neutralization of CD95-ligand and TNF attenuates brain damage in stroke

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Fas receptor and neuronal cell death after spinal cord ischemia

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Delayed-type hypersensitivity lesions in the central nervous system are prevented by inhibitors of matrix metalloproteinases.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Effect of a short-term in vitro exposure to the marine toxin domoic acid on viability, tumor necrosis factor-alpha, matrix metalloproteinase-9 and superoxide anion release by rat neonatal microglia

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Matrix metalloproteinases: multifunctional contributors to tumor progression

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Tumor progression: defining the soil round the tumor seed

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Proteolytic degradation of Alzheimer's disease amyloid beta-peptide by a metalloproteinase from microglia cells.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Fas-mediated apoptosis in Ewing's sarcoma cell lines by metalloproteinase inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Matrix Metalloproteinase Expression After Human Cardioembolic Stroke

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Matrix metalloproteinase expression is related to hemorrhagic transformation after cardioembolic stroke.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Matrix metalloproteinase-9 pretreatment level predicts intracranial hemorrhagic complications after thrombolysis in human stroke.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Subcellular distribution of tight junction-associated proteins (occludin, ZO-1, ZO-2) in rodent skin.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Matrix metalloproteinases in cerebrovascular disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Designing TIMP (tissue inhibitor of metalloproteinases) variants that are selective metalloproteinase inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Matrix metalloproteinases

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Matrix metalloproteinases: biologic activity and clinical implications

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Upregulation of the Fas receptor death-inducing signaling complex after traumatic brain injury in mice and humans.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Mechanisms of angiogenesis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Gelatinase B and TIMP-1 are regulated in a cell- and time-dependent manner in association with neuronal death and glial reactivity after global forebrain ischemia.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Fas (CD95/APO-1) plays a role in the pathophysiology of focal cerebral ischemia

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Matrix metalloproteinases in brain injury

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Matrix metalloproteinases and neuroinflammation in multiple sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Matrix metalloproteinases in neuroinflammation

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

TIMP-2 reduces proteolytic opening of blood-brain barrier by type IV collagenase

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Immunohistochemistry of matrix metalloproteinases in reperfusion injury to rat brain: activation of MMP-9 linked to stromelysin-1 and microglia in cell cultures.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

New drugs on the horizon: matrix metalloproteinase inhibitors

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Neuronal extracellular proteases facilitate cell migration, axonal growth, and pathfinding

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

How matrix metalloproteinases regulate cell behavior

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Regulation of tissue inhibitor of metalloproteinase-1 by astrocytes: links to HIV-1 dementia.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Tissue inhibitor of metalloproteinase 1 inhibits excitotoxic cell death in neurons

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Interleukin-1 is a key regulator of matrix metalloproteinase-9 expression in human neurons in culture and following mouse brain trauma in vivo

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

The tight-junction-specific protein ZO-1 is a component of the human and rat blood-brain barriers.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Matrix-degrading proteases and angiogenesis during development and tumor formation.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Tissue inhibitor of metalloproteinases-3 and matrix metalloproteinase-3 regulate neuronal sensitivity to doxorubicin-induced apoptosis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Vulnerability of mouse cortical neurons to doxorubicin-induced apoptosis is strain-dependent and is correlated with mRNAs encoding Fas, Fas-Ligand, and metalloproteinases

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Metalloproteinases in biology and pathology of the nervous system.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

TIMP-3 binds to sulfated glycosaminoglycans of the extracellular matrix

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Differential inhibition of membrane type 3 (MT3)-matrix metalloproteinase (MMP) and MT1-MMP by tissue inhibitor of metalloproteinase (TIMP)-2 and TIMP-3 rgulates pro-MMP-2 activation.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20169

7 January 2021

Identifiers

DOI

10.1002/GLIA.20169

1 reference

12 August 2017

1 reference

PubMed ID

15846802