(Q36119870)

English

Control of phenotypic plasticity of smooth muscle cells by bone morphogenetic protein signaling through the myocardin-related transcription factors

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scholarly article

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Europe PubMed Central

PMC publication ID

12 August 2017

Control of phenotypic plasticity of smooth muscle cells by bone morphogenetic protein signaling through the myocardin-related transcription factors (English)

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

phenotypic plasticity

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1 reference

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author name string

Giorgio Lagna

1

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Manching M Ku

2

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Peter H Nguyen

3

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Nicole A Neuman

4

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Brandi N Davis

5

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Akiko Hata

6

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

language of work or name

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publication date

17 October 2007

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

282

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

51

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

37244-37255

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Pulmonary arterial hypertension: current therapeutic strategies

1 reference

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2 October 2017

Vascular calcification: pathobiological mechanisms and clinical implications

1 reference

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2 October 2017

Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells

1 reference

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2 October 2017

BMP-dependent activation of caspase-9 and caspase-8 mediates apoptosis in pulmonary artery smooth muscle cells

1 reference

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2 October 2017

Bone morphogenetic protein-induced MSX1 and MSX2 inhibit myocardin-dependent smooth muscle gene transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Vascular smooth muscle cell phenotypic plasticity and the regulation of vascular calcification.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

The myocardin family of transcriptional coactivators: versatile regulators of cell growth, migration, and myogenesis

1 reference

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2 October 2017

Transforming growth factor-betas and vascular disorders

1 reference

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The Rac and Rho hall of fame: a decade of hypertrophic signaling hits

1 reference

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2 October 2017

Role of small GTPases in endothelial cytoskeletal dynamics and the shear stress response

1 reference

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2 October 2017

OAZ regulates bone morphogenetic protein signaling through Smad6 activation

1 reference

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2 October 2017

Downregulation of type II bone morphogenetic protein receptor in hypoxic pulmonary hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Myocardin enhances Smad3-mediated transforming growth factor-beta1 signaling in a CArG box-independent manner: Smad-binding element is an important cis element for SM22alpha transcription in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Rho and vascular disease

1 reference

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2 October 2017

Transforming growth factor-beta1-induced expression of smooth muscle marker genes involves activation of PKN and p38 MAPK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Notch signaling represses myocardin-induced smooth muscle cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Kruppel-like factor 4 abrogates myocardin-induced activation of smooth muscle gene expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF

1 reference

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2 October 2017

Activation of LIMK1 by binding to the BMP receptor, BMPRII, regulates BMP-dependent dendritogenesis

1 reference

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2 October 2017

Molecular regulation of vascular smooth muscle cell differentiation in development and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Genetic basis of pulmonary arterial hypertension: current understanding and future directions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Transforming growth factor beta and atherosclerosis: so far, so good for the protective cytokine hypothesis

1 reference

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2 October 2017

Functional interaction between BMPR-II and Tctex-1, a light chain of Dynein, is isoform-specific and disrupted by mutations underlying primary pulmonary hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Direct signaling by the BMP type II receptor via the cytoskeletal regulator LIMK1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Serum response factor: toggling between disparate programs of gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Actin dynamics control SRF activity by regulation of its coactivator MAL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Hereditary hemorrhagic telangiectasia: an update on transforming growth factor beta signaling in vasculogenesis and angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Krüppel-like factor 4 (KLF4/GKLF) is a target of bone morphogenetic proteins and transforming growth factor beta 1 in the regulation of vascular smooth muscle cell phenotype.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Potentiation of serum response factor activity by a family of myocardin-related transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Functional heterogeneity of bone morphogenetic protein receptor-II mutants found in patients with primary pulmonary hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Signal transduction by the TGF-beta superfamily

1 reference

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2 October 2017

Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Altered growth responses of pulmonary artery smooth muscle cells from patients with primary pulmonary hypertension to transforming growth factor-beta(1) and bone morphogenetic proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Involvement of a human gene related to the Drosophila spen gene in the recurrent t(1;22) translocation of acute megakaryocytic leukemia

1 reference

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2 October 2017

BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

TGFbeta signaling in growth control, cancer, and heritable disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-beta family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

HRT1, HRT2, and HRT3: a new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Roles of bone morphogenetic protein type I receptors and Smad proteins in osteoblast and chondroblast differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Id genes are direct targets of bone morphogenetic protein induction in embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Changes in the balance of phosphoinositide 3-kinase/protein kinase B (Akt) and the mitogen-activated protein kinases (ERK/p38MAPK) determine a phenotype of visceral and vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Regulation of smooth muscle alpha-actin expression in vivo is dependent on CArG elements within the 5' and first intron promoter regions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

TGF-beta signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Smooth muscle-specific expression of the smooth muscle myosin heavy chain gene in transgenic mice requires 5'-flanking and first intronic DNA sequence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

1 reference

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2 October 2017

Inhibition of rat vascular smooth muscle proliferation in vitro and in vivo by bone morphogenetic protein-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Evidence for serum response factor-mediated regulatory networks governing SM22alpha transcription in smooth, skeletal, and cardiac muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

A transforming growth factor beta (TGFbeta) control element drives TGFbeta-induced stimulation of smooth muscle alpha-actin gene expression in concert with two CArG elements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Bone morphogenetic proteins: multifunctional regulators of vertebrate development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Regulation of differentiation of vascular smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

The smooth muscle cell in culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 October 2017

Bone morphogenetic protein signaling modulates myocardin transactivation of cardiac genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 July 2018

Use and properties of ROCK-specific inhibitor Y-27632.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

2 July 2018

Smooth muscle cell-specific transcription is regulated by nuclear localization of the myocardin-related transcription factors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

23 September 2018

Serotonin increases susceptibility to pulmonary hypertension in BMPR2-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

23 September 2018

Involvement of RhoA/Rho kinase signaling in pulmonary hypertension of the fawn-hooded rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

23 September 2018

BMPR-II heterozygous mice have mild pulmonary hypertension and an impaired pulmonary vascular remodeling response to prolonged hypoxia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

23 September 2018

Primary pulmonary hypertension in families with hereditary haemorrhagic telangiectasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

23 September 2018

Expression of genes in the TGF-beta signaling pathway is significantly deregulated in smooth muscle cells from aorta of aryl hydrocarbon receptor knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

23 September 2018

Simvastatin rescues rats from fatal pulmonary hypertension by inducing apoptosis of neointimal smooth muscle cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

23 September 2018

Signaling molecules in nonfamilial pulmonary hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

23 September 2018

Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

23 September 2018

Expression of PDGF-A, TGFb and VCAM-1 during the developmental stages of experimental atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405982

23 September 2018

Relationship of BMPR2 mutations to vasoreactivity in pulmonary arterial hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/17947237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone morphogenetic proteins induce apoptosis in human pulmonary vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17947237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dysregulated Bone Morphogenetic Protein Signaling in Monocrotaline-Induced Pulmonary Arterial Hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/17947237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum response factor-dependent regulation of the smooth muscle calponin gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/17947237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone morphogenetic protein-7 (osteogenic protein-1) inhibits smooth muscle cell proliferation and stimulates the expression of markers that are characteristic of SMC phenotype in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/17947237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of multiple bone morphogenetic protein messenger ribonucleic acids and their signal transducer, Smad1, during mouse decidualization

1 reference

https://pubmed.ncbi.nlm.nih.gov/17947237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primary pulmonary hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/17947237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BMP-2 gene expression and effects on human vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17947237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bone morphogenetic proteins and vascular differentiation: BMPing up vasculogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17947237

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M708137200

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

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