(Q36124489)

12 August 2017

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title

Role of formyl peptide receptor-like 1 (FPRL1/FPR2) in mononuclear phagocyte responses in Alzheimer disease (English)

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12 August 2017

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Yingying Le

4

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author name string

Pablo Iribarren

1

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12 August 2017

Ye Zhou

2

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12 August 2017

Jinyue Hu

3

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12 August 2017

Ji Ming Wang

5

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12 August 2017

1 January 2005

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12 August 2017

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12 August 2017

31

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12 August 2017

165-176

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12 August 2017

3

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https://scigraph.springernature.com/pub.10.1385/ir:31:3:165

12 August 2017

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cites work

Beta amyloid peptide (Abeta42) is internalized via the G-protein-coupled receptor FPRL1 and forms fibrillar aggregates in macrophages.

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12 December 2020

Amyloid beta protein (A beta) removal by neuroglial cells in culture

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12 December 2020

Modulation of monocyte chemotactic function in inflammatory lesions. Role of inflammatory mediators

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12 December 2020

Chemotactic-like receptors and Abeta peptide induced responses in Alzheimer's disease.

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12 December 2020

Evidence that the 42- and 40-amino acid forms of amyloid beta protein are generated from the beta-amyloid precursor protein by different protease activities

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12 December 2020

Insights into the neurodegenerative process of Alzheimer's disease: a role for mononuclear phagocyte-associated inflammation and neurotoxicity

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12 December 2020

Complement gene expression in mouse microglia and astrocytes in culture: comparisons with mouse peritoneal macrophages

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12 December 2020

Uptake, degradation, and release of fibrillar and soluble forms of Alzheimer's amyloid beta-peptide by microglial cells.

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12 December 2020

The serine/threonine phosphatase, PP2A: endogenous regulator of inflammatory cell signaling.

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12 December 2020

Amyloid-beta induces chemokine secretion and monocyte migration across a human blood--brain barrier model

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12 December 2020

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

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12 December 2020

The amyloid beta-protein of Alzheimer's disease is chemotactic for mononuclear phagocytes

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12 December 2020

Bacterial lipopolysaccharide selectively up-regulates the function of the chemotactic peptide receptor formyl peptide receptor 2 in murine microglial cells.

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12 December 2020

Kinetics of N-formyl peptide receptor up-regulation during stimulation in human neutrophils

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12 December 2020

Rodent models of Alzheimer's disease: rat A beta infusion approaches to amyloid deposits

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12 December 2020

Functional expression of the CXC-chemokine receptor-4/fusin on mouse microglial cells and astrocytes.

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12 December 2020

Inflammation of the brain in Alzheimer's disease: implications for therapy.

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12 December 2020

A burgeoning family of biological mediators: chemokines and chemokine receptors

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12 December 2020

Glia: the not so innocent bystanders.

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12 December 2020

Activated microglial cells are colocalized with perivascular deposits of amyloid-beta protein in Alzheimer's disease brain

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12 December 2020

Expression of the receptors for the C5a anaphylatoxin, interleukin-8 and FMLP by human astrocytes and microglia

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12 December 2020

Inflammatory repertoire of Alzheimer's disease and nondemented elderly microglia in vitro.

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12 December 2020

Translating cell biology into therapeutic advances in Alzheimer's disease

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12 December 2020

Bacterial lipopolysaccharide rapidly inhibits expression of C-C chemokine receptors in human monocytes

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12 December 2020

Comparison of phenotypic and functional properties of immediately ex vivo and cultured human adult microglia.

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12 December 2020

Mitosis and apoptosis of microglia in vivo induced by an anti-CR3 antibody which crosses the blood-brain barrier

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12 December 2020

Cultured rat microglia express functional beta-chemokine receptors

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12 December 2020

Intratracheal injection of endotoxin and cytokines. II. Interleukin-6 and transforming growth factor beta inhibit acute inflammation

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12 December 2020

Detection of complement alternative pathway mRNA and proteins in the Alzheimer's disease brain.

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12 December 2020

Interleukin 10 increases CCR5 expression and HIV infection in human monocytes

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12 December 2020

The many faces of macrophage activation

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12 December 2020

Inhibitors of protein phosphatase 1 and 2A differentially regulate the expression of inducible nitric-oxide synthase in rat astrocytes and macrophages.

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12 December 2020

Gene expression profiling of amyloid beta peptide-stimulated human post-mortem brain microglia

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12 December 2020

Pathways of inflammatory activation in Alzheimer's disease: potential targets for disease modifying drugs

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12 December 2020

Characterization of microglia and macrophages in the central nervous system of rats: definition of the differential expression of molecules using standard and novel monoclonal antibodies in normal CNS and in four models of parenchymal reaction.

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12 December 2020

Complement and cytokine gene expression in cultured microglial derived from postmortem human brains

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12 December 2020

Visualization of beta-amyloid peptide (Abeta) phagocytosis by human mononuclear phagocytes: dependency on Abeta aggregate size

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12 December 2020

TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice.

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12 December 2020

Inflammation and Alzheimer's disease: relationships between pathogenic mechanisms and clinical expression.

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12 December 2020

Phenotypic diversity and kinetics of proliferating microglia and astrocytes following cortical stab wounds.

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12 December 2020

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

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12 December 2020

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12 December 2020

Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils

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12 December 2020

Microglia and astroglia have a common progenitor cell

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12 December 2020

The origin of amyloid in cerebral vessels of aged dogs

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12 December 2020

Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer's disease.

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12 December 2020

beta-Amyloid-induced IL-1 beta release from an activated human monocyte cell line is calcium- and G-protein-dependent

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12 December 2020

Interleukin-1 injected into mammalian brain stimulates astrogliosis and neovascularization

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12 December 2020

Regulation of immune responses by TGF-beta

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12 December 2020

Regulation of amyloid precursor protein cleavage.

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12 December 2020

Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome.

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12 December 2020

A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ

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12 December 2020

Transforming growth factor-beta inhibits lipopolysaccharide-stimulated expression of inflammatory cytokines in mouse macrophages through downregulation of activation protein 1 and CD14 receptor expression

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12 December 2020

Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism.

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12 December 2020

Lipopolysaccharide modulates receptors for leukotriene B4, C5a, and formyl-methionyl-leucyl-phenylalanine on rabbit polymorphonuclear leukocytes

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12 December 2020

Utilization of two seven-transmembrane, G protein-coupled receptors, formyl peptide receptor-like 1 and formyl peptide receptor, by the synthetic hexapeptide WKYMVm for human phagocyte activation

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12 December 2020

Alzheimer's disease: genes, proteins, and therapy

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12 December 2020

Escherichia coli-induced activation of neutrophil NADPH-oxidase: lipopolysaccharide and formylated peptides act synergistically to induce release of reactive oxygen metabolites

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12 December 2020

Fibrillar beta-amyloid induces microglial phagocytosis, expression of inducible nitric oxide synthase, and loss of a select population of neurons in the rat CNS in vivo.

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12 December 2020

Complement 5a controls motility of murine microglial cells in vitro via activation of an inhibitory G-protein and the rearrangement of the actin cytoskeleton

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12 December 2020

Recognition of gram-negative bacteria and endotoxin by the innate immune system

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12 December 2020

Microglial chemotaxis, activation, and phagocytosis of amyloid beta-peptide as linked phenomena in Alzheimer's disease

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12 December 2020

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death

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12 December 2020

Evidence for in vivo production of Humanin peptide, a neuroprotective factor against Alzheimer's disease-related insults

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12 December 2020

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

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12 December 2020

Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

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12 December 2020

The role of mononuclear phagocytes in wound healing after traumatic injury to adult mammalian brain

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12 December 2020

Priming induces functional coupling of N -formyl-methionyl-leucyl-phenylalanine receptors in equine neutrophils

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12 December 2020

Chemotaxis by a CNS macrophage, the microglia

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12 December 2020

Up-regulation of the inflammatory cytokines IFN-gamma and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APP(SWE) transgenic mice.

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12 December 2020

The Increasing Burden of Alzheimer Disease

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12 December 2020

TGF-beta1 disrupts endotoxin signaling in microglial cells through Smad3 and MAPK pathways

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12 December 2020

Axotomy of the rat facial nerve leads to increased CR3 complement receptor expression by activated microglial cells

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12 December 2020

Arrest of endotoxin-induced hypotension by transforming growth factor beta1.

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12 December 2020

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

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12 December 2020

Amyloid-beta induces chemotaxis and oxidant stress by acting at formylpeptide receptor 2, a G protein-coupled receptor expressed in phagocytes and brain

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12 December 2020

Enhanced expression of chemotactic receptors in multiple sclerosis lesions.

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12 December 2020

Neuronal expression of mRNAs for complement proteins of the classical pathway in Alzheimer brain.

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12 December 2020

IL-4 Down-Regulates Lipopolysaccharide-Induced Formyl Peptide Receptor 2 in Murine Microglial Cells by Inhibiting the Activation of Mitogen-Activated Protein Kinases

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12 December 2020

Humanin, a newly identified neuroprotective factor, uses the G protein-coupled formylpeptide receptor-like-1 as a functional receptor

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12 December 2020

Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide production in microglia.

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12 December 2020

Alternative activation of macrophages

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12 December 2020

Synthetic Alzheimer amyloid beta/A4 peptides enhance production of complement C3 component by cultured microglial cells.

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12 December 2020

The pathogenesis of senile plaques

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12 December 2020

PKC and tyrosine kinase involvement in amyloid beta (25-35)-induced chemotaxis of microglia.

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12 December 2020

Regulation of stress-activated protein kinase signaling pathways by protein phosphatases

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12 December 2020

Amyloid (beta)42 activates a G-protein-coupled chemoattractant receptor, FPR-like-1

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12 December 2020

Synaptic density in the inner molecular layer of the hippocampal dentate gyrus in Alzheimer disease.

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12 December 2020

Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain

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12 December 2020

Up-regulation of FPR2, a chemotactic receptor for amyloid beta 1-42 (A beta 42), in murine microglial cells by TNF alpha

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12 December 2020

Formyl-peptide receptors revisited

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12 December 2020

The bacterial endotoxin lipopolysaccharide has the ability to target the brain in upregulating its membrane CD14 receptor within specific cellular populations

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12 December 2020

Transcription factor NF-kappa B is activated in microglia during experimental autoimmune encephalomyelitis

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12 December 2020

Identifiers

DOI

10.1385/IR:31:3:165

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Dimensions Publication ID

12 August 2017

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