(Q36126992)

English

The cytosolic domain of protein-tyrosine kinase 7 (PTK7), generated from sequential cleavage by a disintegrin and metalloprotease 17 (ADAM17) and γ-secretase, enhances cell proliferation and migration in colon cancer cells

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scholarly article

1 reference

Europe PubMed Central

12 August 2017

The cytosolic domain of protein-tyrosine kinase 7 (PTK7), generated from sequential cleavage by a disintegrin and metalloprotease 17 (ADAM17) and γ-secretase, enhances cell proliferation and migration in colon cancer cells (English)

1 reference

Europe PubMed Central

12 August 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

object named as

Won-Sik Shin

2

0 references

object named as

Seung-Taek Lee

4

0 references

object named as

Andreas Ludwig

3

0 references

author name string

Hye-Won Na

1

1 reference

Europe PubMed Central

12 August 2017

language of work or name

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publication date

4 June 2012

1 reference

Europe PubMed Central

12 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

12 August 2017

287

1 reference

Europe PubMed Central

12 August 2017

30

1 reference

Europe PubMed Central

12 August 2017

25001-25009

1 reference

Europe PubMed Central

12 August 2017

The many roles of PTK7: A versatile regulator of cell–cell communication

1 reference

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The ADAMs family of proteases: new biomarkers and therapeutic targets for cancer?

1 reference

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PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling

1 reference

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The many substrates of presenilin/γ-secretase

1 reference

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Expression profiling of liposarcoma yields a multigene predictor of patient outcome and identifies genes that contribute to liposarcomagenesis.

1 reference

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Protein tyrosine kinase 7 has a conserved role in Wnt/β-catenin canonical signalling

1 reference

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Silencing of PTK7 in colon cancer cells: caspase-10-dependent apoptosis via mitochondrial pathway

1 reference

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The Wnt/planar cell polarity protein-tyrosine kinase-7 (PTK7) is a highly efficient proteolytic target of membrane type-1 matrix metalloproteinase: implications in cancer and embryogenesis.

1 reference

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The cell polarity PTK7 receptor acts as a modulator of the chemotherapeutic response in acute myeloid leukemia and impairs clinical outcome

1 reference

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Identification of serum biomarkers for colorectal cancer metastasis using a differential secretome approach

1 reference

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Matrix metalloproteinases as novel biomarkers and potential therapeutic targets in human cancer

1 reference

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Identification of ligand-induced proteolytic cleavage and ectodomain shedding of VEGFR-1/FLT1 in leukemic cancer cells

1 reference

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The "a disintegrin and metalloprotease" (ADAM) family of sheddases: physiological and cellular functions

1 reference

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The ADAMs: signalling scissors in the tumour microenvironment

1 reference

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PTK7 recruits dsh to regulate neural crest migration

1 reference

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The ADAM metalloproteinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408140

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Substrate specificity of gamma-secretase and other intramembrane proteases

1 reference

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ADAM-17 expression in breast cancer correlates with variables of tumor progression.

1 reference

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Presenilin-dependent ErbB4 nuclear signaling regulates the timing of astrogenesis in the developing brain

1 reference

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Aberrant expression of a disintegrin and metalloproteinase 17/tumor necrosis factor-alpha converting enzyme increases the malignant potential in human pancreatic ductal adenocarcinoma

1 reference

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Multiple acquired renal carcinoma tumor capabilities abolished upon silencing of ADAM17.

1 reference

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Metalloproteinase/Presenilin1 processing of ephrinB regulates EphB-induced Src phosphorylation and signaling

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Biomarker discovery from pancreatic cancer secretome using a differential proteomic approach

1 reference

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Up-regulated expression of ADAM17 in human colon carcinoma: co-expression with EGFR in neoplastic and endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408140

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An intramolecular interaction between SH2-kinase linker and kinase domain is essential for the catalytic activity of protein-tyrosine kinase-6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408140

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Shedding light on ADAM metalloproteinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408140

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Metalloproteinase inhibitors for the disintegrin-like metalloproteinases ADAM10 and ADAM17 that differentially block constitutive and phorbol ester-inducible shedding of cell surface molecules.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408140

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Increased expression of ADAM family members in human breast cancer and breast cancer cell lines

1 reference

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ADAM17 mRNA expression and pathological features of hepatocellular carcinoma

1 reference

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PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates

1 reference

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Cloning and characterization of the full-length mouse Ptk7 cDNA encoding a defective receptor protein tyrosine kinase

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Expression of ADAMs (a disintegrin and metalloproteases) and TIMP-3 (tissue inhibitor of metalloproteinase-3) in human prostatic adenocarcinomas

1 reference

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1 reference

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1 reference

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1 reference

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Characterization of the human full-length PTK7 cDNA encoding a receptor protein tyrosine kinase-like molecule closely related to chick KLG.

1 reference

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1 reference

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.348904

1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

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