(Q36127016)

12 August 2017

Microtubule capture by mitotic kinesin centromere protein E (CENP-E). (English)

1 reference

12 August 2017

Harjinder S Sardar

1

1 reference

12 August 2017

Susan P Gilbert

series ordinal

2

1 reference

12 August 2017

language of work or name

English

0 references

publication date

27 May 2012

1 reference

Journal of Biological Chemistry

12 August 2017

1 reference

12 August 2017

287

1 reference

12 August 2017

30

1 reference

12 August 2017

24894-24904

1 reference

The loop 5 element structurally and kinetically coordinates dimers of the human kinesin-5, Eg5.

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Kinetochores and disease: keeping microtubule dynamics in check!

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Interhead tension determines processivity across diverse N-terminal kinesins

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

The spatial arrangement of chromosomes during prometaphase facilitates spindle assembly

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

A universal pathway for kinesin stepping

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Kinesin Kar3Cik1 ATPase pathway for microtubule cross-linking.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Loop L5 acts as a conformational latch in the mitotic kinesin Eg5

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Mitotic kinesin CENP-E promotes microtubule plus-end elongation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Aurora kinases and protein phosphatase 1 mediate chromosome congression through regulation of CENP-E.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

The conserved L5 loop establishes the pre-powerstroke conformation of the Kinesin-5 motor, eg5

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Allosteric drug discrimination is coupled to mechanochemical changes in the kinesin-5 motor core

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Mechanisms of chromosome behaviour during mitosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

ATP hydrolysis in Eg5 kinesin involves a catalytic two-water mechanism

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Deviant kinetochore microtubule dynamics underlie chromosomal instability.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

The ATPase cycle of the mitotic motor CENP-E.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Why kinesin is so processive

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Docking motif-guided mapping of the interactome of protein phosphatase-1

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

CENP-E combines a slow, processive motor and a flexible coiled coil to produce an essential motile kinetochore tether

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

The mitotic kinesin CENP-E is a processive transport motor.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Getting in sync with dimeric Eg5. Initiation and regulation of the processive run.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

To step or not to step? How biochemistry and mechanics influence processivity in Kinesin and Eg5.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Dimeric Eg5 maintains processivity through alternating-site catalysis with rate-limiting ATP hydrolysis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Backsteps induced by nucleotide analogs suggest the front head of kinesin is gated by strain

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Individual dimers of the mitotic kinesin motor Eg5 step processively and support substantial loads in vitro

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Chromosomes can congress to the metaphase plate before biorientation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Mechanistic analysis of the mitotic kinesin Eg5.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

2 October 2017

Kinesin's second step

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Unstable kinetochore-microtubule capture and chromosomal instability following deletion of CENP-E

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Microtubule-dependent changes in assembly of microtubule motor proteins and mitotic spindle checkpoint proteins at PtK1 kinetochores

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Kinetics: a tool to study molecular motors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

A structural change in the kinesin motor protein that drives motility

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

The vertebrate cell kinetochore and its roles during mitosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Localization of CENP-E in the fibrous corona and outer plate of mammalian kinetochores from prometaphase through anaphase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Cyclin-like accumulation and loss of the putative kinetochore motor CENP-E results from coupling continuous synthesis with specific degradation at the end of mitosis.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Pathway of processive ATP hydrolysis by kinesin.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Kinetochore microtubule dynamics and the metaphase-anaphase transition

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Kinesin ATPase: rate-limiting ADP release

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Bead movement by single kinesin molecules studied with optical tweezers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

CENP-E is a putative kinetochore motor that accumulates just before mitosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Intramolecular strain coordinates kinesin stepping behavior along microtubules

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408146

Aneuploidy acts both oncogenically and as a tumor suppressor

2 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.376830

Movement of microtubules by single kinesin molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.376830

Phosphorylation relieves autoinhibition of the kinetochore motor Cenp-E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.376830

Motor domain mutation traps kinesin as a microtubule rigor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.376830

Measuring kinesin's first step

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.376830

Expression, purification, and characterization of the Drosophila kinesin motor domain produced in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.376830

Alternating site mechanism of the kinesin ATPase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.376830

The kinesin-like protein CENP-E is kinetochore-associated throughout poleward chromosome segregation during anaphase-A

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22637578

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Interacting head mechanism of microtubule-kinesin ATPase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22637578

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Pathway of ATP hydrolysis by monomeric and dimeric kinesin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22637578

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M112.376830

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

22637578

1 reference