(Q36127062)

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DNase I hypersensitive site II of the human growth hormone locus control region mediates an essential and distinct long-range enhancer function

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scholarly article

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Europe PubMed Central

PMC publication ID

12 August 2017

DNase I hypersensitive site II of the human growth hormone locus control region mediates an essential and distinct long-range enhancer function (English)

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

author name string

Margaret R Fleetwood

1

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Yugong Ho

2

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Nancy E Cooke

3

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Stephen A Liebhaber

4

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Europe PubMed Central

PMC publication ID

12 August 2017

language of work or name

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publication date

5 June 2012

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Europe PubMed Central

PMC publication ID

12 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

12 August 2017

287

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Europe PubMed Central

PMC publication ID

12 August 2017

30

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

25454-25465

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3408159/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3408159/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

The hypersensitive sites of the murine β-globin locus control region act independently to affect nuclear localization and transcriptional elongation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

POU1F1-mediated activation of hGH-N by deoxyribonuclease I hypersensitive site II of the human growth hormone locus control region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

Regulating RNA polymerase pausing and transcription elongation in embryonic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

The role of the hGH locus control region in somatotrope restriction of hGH-N gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

c-Myc regulates transcriptional pause release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

Appearance of the pituitary factor Pit-1 increases chromatin remodeling at hypersensitive site III in the human GH locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

The juxtaposition of a promoter with a locus control region transcriptional domain activates gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

Establishment and regulation of chromatin domains: mechanistic insights from studies of hemoglobin synthesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

Locus control region transcription plays an active role in long-range gene activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

Tissue-specific chromatin modifications at a multigene locus generate asymmetric transcriptional interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

On a chromosome far, far away: LCRs and gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

Bystander gene activation by a locus control region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

The beta -globin locus control region (LCR) functions primarily by enhancing the transition from transcription initiation to elongation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

Locus control regions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

Three RNA polymerase II carboxyl-terminal domain kinases display distinct substrate preferences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

Patterns of histone acetylation suggest dual pathways for gene activation by a bifunctional locus control region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

Pit-1 binding sites at the somatotrope-specific DNase I hypersensitive sites I, II of the human growth hormone locus control region are essential for in vivo hGH-N gene activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

DNase I-hypersensitive sites I and II of the human growth hormone locus control region are a major developmental activator of somatotrope gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

The human growth hormone gene is regulated by a multicomponent locus control region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

Transgenic mice containing a 248-kb yeast artificial chromosome carrying the human beta-globin locus display proper developmental control of human globin genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

A 5' element of the chicken beta-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

Selection for loss of tetracycline resistance by Escherichia coli.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

Positive selection for loss of tetracycline resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

Tissue-specific expression of the human growth hormone gene is conferred in part by the binding of a specific trans-acting factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

B29: a member of the immunoglobulin gene superfamily exclusively expressed on beta-lineage cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

A distant gene deletion affects beta-globin gene function in an atypical gamma delta beta-thalassemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

Gamma delta beta-thalassemia due to a de novo mutation deleting the 5' beta-globin gene activation-region hypersensitive sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

IgM antigen receptor complex contains phosphoprotein products of B29 and mb-1 genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

A locus control region adjacent to the human red and green visual pigment genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

The genomic structure of the human skeletal muscle sodium channel gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 October 2017

Deletion of the human beta-globin LCR 5'HS4 or 5'HS1 differentially affects beta-like globin gene expression in beta-YAC transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 July 2018

Cooperativeness of the higher chromatin structure of the beta-globin locus revealed by the deletion mutations of DNase I hypersensitive site 3 of the LCR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 July 2018

Physical linkage of the human growth hormone gene cluster and the CD79b (Ig beta/B29) gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 July 2018

Activation of cell-specific expression of rat growth hormone and prolactin genes by a common transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 July 2018

A deletion of the human beta-globin locus activation region causes a major alteration in chromatin structure and replication across the entire beta-globin locus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408159

2 July 2018

Enhancer-blocking activity is associated with hypersensitive site V sequences in the human growth hormone locus control region.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.365825

21 January 2018

Epigenetic modifications at the human growth hormone locus predict distinct roles for histone acetylation and methylation in placental gene activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.365825

21 January 2018

Physical linkage of the human growth hormone gene cluster and the skeletal muscle sodium channel alpha-subunit gene (SCN4A) on chromosome 17.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.365825

21 January 2018

A defined locus control region determinant links chromatin domain acetylation with long-range gene activation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.365825

21 January 2018

Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.365825

21 January 2018

β-Globin gene inactivation by DNA translocation in γβ-thalassaemi

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.365825

21 January 2018

Dramatic Pituitary Hyperplasia in Transgenic Mice Expressing a Human Growth Hormone-Releasing Factor Gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.365825

21 January 2018

A pituitary-specific trans-acting factor can stimulate transcription from the growth hormone promoter in extracts of nonexpressing cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22669946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human CD2 3'-flanking sequences confer high-level, T cell-specific, position-independent gene expression in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22669946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased gamma-globin gene expression in beta-thalassemia intermedia patients correlates with a mutation in 3'HS1

1 reference

https://pubmed.ncbi.nlm.nih.gov/22669946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human growth hormone gene cluster locus control region supports position-independent pituitary- and placenta-specific expression in the transgenic mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/22669946

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.365825

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

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