(Q36129815)

12 August 2017

MAFA and T3 Drive Maturation of Both Fetal Human Islets and Insulin-Producing Cells Differentiated From hESC (English)

1 reference

12 August 2017

Susan Bonner-Weir

8

0 references

Gordon C. Weir

6

object named as

Gordon Weir

1 reference

12 August 2017

Cristina Aguayo-Mazzucato

1

1 reference

12 August 2017

Amanda DiIenno

2

1 reference

12 August 2017

Jennifer Hollister-Lock

3

1 reference

12 August 2017

Christopher Cahill

4

1 reference

12 August 2017

Arun Sharma

5

1 reference

12 August 2017

Clark Colton

7

1 reference

12 August 2017

language of work or name

English

0 references

publication date

24 July 2015

1 reference

The Journal of Clinical Endocrinology and Metabolism

12 August 2017

1 reference

12 August 2017

100

1 reference

12 August 2017

10

1 reference

12 August 2017

3651-3659

1 reference

Generation of functional human pancreatic β cells in vitro

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596039

Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596039

Differentiated human stem cells resemble fetal, not adult, β cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596039

Thyroid hormone promotes postnatal rat pancreatic β-cell development and glucose-responsive insulin secretion through MAFA.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596039

Maturation of human embryonic stem cell-derived pancreatic progenitors into functional islets capable of treating pre-existing diabetes in mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596039

Mafa expression enhances glucose-responsive insulin secretion in neonatal rat beta cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596039

Production of beta-cells from human embryonic stem cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596039

Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596039

Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596039

A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596039

Exposure of human islets to cytokines can result in disproportionately elevated proinsulin release

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596039

Prolonged exposure of human beta cells to elevated glucose levels results in sustained cellular activation leading to a loss of glucose regulation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596039

Identification and characterization of a functional retinoic acid/thyroid hormone-response element upstream of the human insulin gene enhancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596039

Relationship of receptor affinity to the modulation of thyroid hormone nuclear receptor levels and growth hormone synthesis by L-triiodothyronine and iodothyronine analogues in cultured GH1 cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596039

Functional beta-cell maturation is marked by an increased glucose threshold and by expression of urocortin 3.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596039

Endocrine and metabolic response in the human newborn to first feed of breast milk

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596039

Both relative insulin resistance and defective islet beta-cell processing of proinsulin are responsible for transient hyperglycemia in extremely preterm infants

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596039

Abnormal Insulin Secretion in a Streptozocin Model of Diabetes: Effects of Insulin Treatment

23 September 2018

1 reference

12 December 2020

Impaired insulin secretion associated with near normoglycemia. Study in normal rats with 96-h in vivo glucose infusions

1 reference

12 December 2020

Reproducible high yield of rat islets by stationary in vitro digestion following pancreatic ductal or portal venous collagenase injection

1 reference

12 December 2020

Glucose-induced insulin release in islets of young rats: time-dependent potentiation and effects of 2-bromostearate

1 reference

12 December 2020

Replication of adult pancreatic-beta cells cultured on bovine corneal endothelial cell extracellular matrix

1 reference

12 December 2020

Identifiers

DOI

10.1210/JC.2015-2632

1 reference

12 August 2017

1 reference

12 August 2017

1 reference