(Q36133352)

12 August 2017

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores. (English)

1 reference

12 August 2017

1 reference

linkage disequilibrium

1 reference

Bogdan Pasaniuc

20

0 references

Nikolaos A. Patsopoulos

Nikolaos A Patsopoulos

25

0 references

Hong-Hee Won

Hong-Hee Won

12

0 references

Jian Yang

Jian Yang

2

0 references

Mikkel Heide Schierup

Mikkel H Schierup

23

0 references

Peter M. Visscher

Peter M Visscher

32

0 references

Michael Goddard

Michael Goddard

31

0 references

Sekar Kathiresan

14

Sekar Kathiresan

1 reference

12 August 2017

27

Mark Daly

1 reference

12 August 2017

19

Noah Zaitlen

1 reference

12 August 2017

29

Daniel Chasman

1 reference

12 August 2017

Stephan Ripke

6

0 references

Rulla M Tamimi

17

Rulla Tamimi

1 reference

12 August 2017

22

Eimear E Kenny

1 reference

12 August 2017

34

Nick Patterson

1 reference

12 August 2017

30

Benjamin Neale

1 reference

12 August 2017

15

Michele Pato

1 reference

12 August 2017

18

Eli Stahl

1 reference

12 August 2017

28

Shaun Purcell

1 reference

12 August 2017

35

Alkes L Price

1 reference

12 August 2017

7

Giulio Genovese

1 reference

12 August 2017

9

Gaurav Bhatia

1 reference

12 August 2017

33

Peter Kraft

1 reference

12 August 2017

5

Sara Lindström

1 reference

12 August 2017

Bjarni J Vilhjálmsson

1

1 reference

12 August 2017

Hilary K Finucane

3

1 reference

12 August 2017

Alexander Gusev

4

1 reference

12 August 2017

Po-Ru Loh

8

1 reference

12 August 2017

Ron Do

10

1 reference

12 August 2017

Tristan Hayeck

11

1 reference

12 August 2017

Schizophrenia Working Group of the Psychiatric Genomics Consortium, Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE) study

13

1 reference

12 August 2017

Carlos Pato

16

1 reference

12 August 2017

Gillian Belbin

21

1 reference

12 August 2017

Philip De Jager

24

1 reference

12 August 2017

Steve McCarroll

26

1 reference

12 August 2017

language of work or name

English

0 references

publication date

1 October 2015

1 reference

American Journal of Human Genetics

12 August 2017

1 reference

12 August 2017

97

1 reference

12 August 2017

4

1 reference

12 August 2017

576-592

1 reference

Partitioning heritability by functional annotation using genome-wide association summary statistics

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Explicit Modeling of Ancestry Improves Polygenic Risk Scores and BLUP Prediction

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Simultaneous discovery, estimation and prediction analysis of complex traits using a bayesian mixture model

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Efficient Bayesian mixed-model analysis increases association power in large cohorts.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Defining the role of common variation in the genomic and biological architecture of adult human height

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Biological insights from 108 schizophrenia-associated genetic loci

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

MultiBLUP: improved SNP-based prediction for complex traits

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Meta-analysis of gene-level tests for rare variant association

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Validating therapeutic targets through human genetics

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Pitfalls of predicting complex traits from SNPs

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Pleiotropy in complex traits: challenges and strategies

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Power and predictive accuracy of polygenic risk scores.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Genome-wide association studies identify four ER negative-specific breast cancer risk loci

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Projecting the performance of risk prediction based on polygenic analyses of genome-wide association studies

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Polygenic modeling with bayesian sparse linear mixed models

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Large-scale association analysis identifies new risk loci for coronary artery disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

SparSNP: fast and memory-efficient analysis of all SNPs for phenotype prediction.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

A novel variational Bayes multiple locus Z-statistic for genome-wide association studies with Bayesian model averaging

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Genome-wide association analysis identifies three new breast cancer susceptibility loci

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Genome-wide association study identifies five new schizophrenia loci

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Evaluation of polygenic risk scores for predicting breast and prostate cancer risk

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Genomic inflation factors under polygenic inheritance

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Estimating missing heritability for disease from genome-wide association studies

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Predicting genetic predisposition in humans: the promise of whole-genome markers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Hundreds of variants clustered in genomic loci and biological pathways affect human height

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Evidence for polygenic susceptibility to multiple sclerosis--the shape of things to come

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

The genetic interpretation of area under the ROC curve in genomic profiling

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

From disease association to risk assessment: an optimistic view from genome-wide association studies on type 1 diabetes.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

The limits of individual identification from sample allele frequencies: theory and statistical analysis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Harnessing the information contained within genome-wide association studies to improve individual prediction of complex disease risk

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Accuracy of predicting the genetic risk of disease using a genome-wide approach

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Genomic selection: prediction of accuracy and maximisation of long term response

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Rationale, design, and methodology of the Women's Genome Health Study: a genome-wide association study of more than 25,000 initially healthy american women

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

A fast algorithm for BayesB type of prediction of genome-wide estimates of genetic value

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Effective genetic-risk prediction using mixed models

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

A better coefficient of determination for genetic profile analysis

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Technical note: Computing strategies in genome-wide selection.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Improving accuracy of genomic predictions within and between dairy cattle breeds with imputed high-density single nucleotide polymorphism panels

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4596916

Polygenes, risk prediction, and targeted prevention of breast cancer

5 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26430803

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.AJHG.2015.09.001

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

26430803

1 reference