(Q36155073)

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Blockade of the activin receptor IIb activates functional brown adipogenesis and thermogenesis by inducing mitochondrial oxidative metabolism

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Europe PubMed Central

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1 February 2020

Blockade of the activin receptor IIb activates functional brown adipogenesis and thermogenesis by inducing mitochondrial oxidative metabolism (English)

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1 February 2020

Activin A receptor type 2B

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GOA release 2020-03-11

negative regulation of cold-induced thermogenesis

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GOA release 2020-03-11

Activin receptor IIB

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GOA release 2020-03-11

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based on heuristic

inferred from title

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based on heuristic

inferred from title

Shinji Hatakeyama

11

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1 February 2020

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Brigitte Fournier

1

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1 February 2020

Ben Murray

2

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1 February 2020

Sabine Gutzwiller

3

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1 February 2020

Stefan Marcaletti

4

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1 February 2020

David Marcellin

5

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1 February 2020

Sebastian Bergling

6

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1 February 2020

Sophie Brachat

7

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1 February 2020

Elke Persohn

8

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1 February 2020

Eliane Pierrel

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1 February 2020

Florian Bombard

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1 February 2020

Anne-Ulrike Trendelenburg

12

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1 February 2020

Frederic Morvan

13

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1 February 2020

Brian Richardson

14

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1 February 2020

David J Glass

15

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1 February 2020

Estelle Lach-Trifilieff

16

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1 February 2020

Jerome N Feige

17

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1 February 2020

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14 May 2012

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1 February 2020

Molecular and Cellular Biology

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1 February 2020

32

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1 February 2020

14

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1 February 2020

2871-2879

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1 February 2020

A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Sarcopenia and obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Protection from obesity and diabetes by blockade of TGF-β/Smad3 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Separation of the gluconeogenic and mitochondrial functions of PGC-1{alpha} through S6 kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Smad3 deficiency in mice protects against insulin resistance and obesity induced by a high-fat diet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

METABOLIC FUNCTIONS OF MYOSTATIN AND GDF11.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Emerging roles for the transforming growth factor-{beta} superfamily in regulating adiposity and energy expenditure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Brown adipose tissue: a promising target to combat obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Akt deficiency attenuates muscle size and function but not the response to ActRIIB inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Postnatal PPARdelta activation and myostatin inhibition exert distinct yet complimentary effects on the metabolic profile of obese insulin-resistant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

The changed metabolic world with human brown adipose tissue: therapeutic visions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Brown fat as a therapy for obesity and diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Emerging role of bone morphogenetic proteins in adipogenesis and energy metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Proteome differences between brown and white fat mitochondria reveal specialized metabolic functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

The effects of a soluble activin type IIB receptor on obesity and insulin sensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Functional brown adipose tissue in healthy adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Identification and importance of brown adipose tissue in adult humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Cold-activated brown adipose tissue in healthy men

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Myostatin inhibition in muscle, but not adipose tissue, decreases fat mass and improves insulin sensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

UCP1: its involvement and utility in obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

PRDM16 controls a brown fat/skeletal muscle switch

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Sarcopenic obesity: a new category of obesity in the elderly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Transcriptional control of brown fat determination by PRDM16

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Unexpected evidence for active brown adipose tissue in adult humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

FSTL3 deletion reveals roles for TGF-beta family ligands in glucose and fat homeostasis in adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Regulation of muscle growth by multiple ligands signaling through activin type II receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Regulation of muscle mass by myostatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Myoglobin: an essential hemoprotein in striated muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Myostatin Signals through a Transforming Growth Factor β-Like Signaling Pathway To Block Adipogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Inhibition of myostatin in adult mice increases skeletal muscle mass and strength

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Suppression of body fat accumulation in myostatin-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Regulation of myostatin activity and muscle growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 October 2017

Depressed thermogenesis but competent brown adipose tissue recruitment in mice devoid of all hormone-binding thyroid hormone receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

2 July 2018

Myostatin inhibits brown adipocyte differentiation via regulation of Smad3-mediated β-catenin stabilization.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

23 September 2018

Myostatin-deficient mice exhibit reduced insulin resistance through activating the AMP-activated protein kinase signalling pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

23 September 2018

Myostatin inhibition enhances the effects of exercise on performance and metabolic outcomes in aged mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

23 September 2018

Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

23 September 2018

Muscle-specific expression of PPARgamma coactivator-1alpha improves exercise performance and increases peak oxygen uptake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416189

23 September 2018

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10.1128/MCB.06575-11

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1 February 2020

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1 February 2020

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1 February 2020

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