(Q36158687)

12 August 2017

1 reference

title

Inhibition of GSK-3beta as a target for cardioprotection: the importance of timing, location, duration and degree of inhibition (English)

1 reference

12 August 2017

Elizabeth Murphy

1

1 reference

12 August 2017

Charles Steenbergen

series ordinal

2

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12 August 2017

language of work or name

English

0 references

publication date

1 June 2005

1 reference

Expert Opinion on Therapeutic Targets

12 August 2017

published in

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12 August 2017

volume

9

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12 August 2017

issue

3

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12 August 2017

page(s)

447-456

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Myocardial protection at a crossroads: the need for translation into clinical therapy

12 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Glycogen synthase kinase-3beta mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Inhibit GSK-3beta or there's heartbreak dead ahead

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

A-kinase anchoring protein AKAP220 binds to glycogen synthase kinase-3beta (GSK-3beta ) and mediates protein kinase A-dependent inhibition of GSK-3beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Regulation of glycogen synthesis by amino acids in cultured human muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Dual regulation of glycogen synthase kinase-3beta by the alpha1A-adrenergic receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

The activation of glycogen synthase by insulin switches from kinase inhibition to phosphatase activation during adipogenesis in 3T3-L1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Convergence of multiple signaling cascades at glycogen synthase kinase 3: Edg receptor-mediated phosphorylation and inactivation by lysophosphatidic acid through a protein kinase C-dependent intracellular pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Cyclic AMP promotes neuronal survival by phosphorylation of glycogen synthase kinase 3beta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Amino acid- and lipid-induced insulin resistance in rat heart: molecular mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Signalling pathways and combinatory effects of insulin and amino acids in isolated rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Further evidence that the tyrosine phosphorylation of glycogen synthase kinase-3 (GSK3) in mammalian cells is an autophosphorylation event

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Wnt signaling controls the phosphorylation status of beta-catenin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Complex formation of adenomatous polyposis coli gene product and axin facilitates glycogen synthase kinase-3 beta-dependent phosphorylation of beta-catenin and down-regulates beta-catenin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Differential regulation of glycogen synthase kinase 3beta by insulin and Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Suppression of glycogen synthase kinase activity is not sufficient for leukemia enhancer factor-1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Glycogen synthase kinase 3beta regulates GATA4 in cardiac myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Glycogen synthase kinase-3beta is a negative regulator of cardiomyocyte hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Proapoptotic stimuli induce nuclear accumulation of glycogen synthase kinase-3 beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

The regulation of glycogen synthase kinase-3 nuclear export by Frat/GBP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Glycogen synthase kinase-3beta phosphorylates Bax and promotes its mitochondrial localization during neuronal apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Role of tau phosphorylation by glycogen synthase kinase-3beta in the regulation of organelle transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

MAPK and Akt act cooperatively but independently on hypoxia inducible factor-1alpha in rasV12 upregulation of VEGF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Phosphorylation by glycogen synthase kinase-3 beta down-regulates Notch activity, a link for Notch and Wnt pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Glycogen synthase kinase-3 enhances nuclear export of a Dictyostelium STAT protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Regulatory role of glycogen synthase kinase 3 for transcriptional activity of ADD1/SREBP1c

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Regulation of mitochondrial pyruvate dehydrogenase activity by tau protein kinase I/glycogen synthase kinase 3beta in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Phosphorylation of insulin receptor substrate 1 by glycogen synthase kinase 3 impairs insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Glycogen synthase kinase 3 beta is a natural activator of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 1 (MEKK1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin-based motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

The glamour and gloom of glycogen synthase kinase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

NGF-induced axon growth is mediated by localized inactivation of GSK-3beta and functions of the microtubule plus end binding protein APC

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Central role of glycogen synthase kinase-3beta in endoplasmic reticulum stress-induced caspase-3 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

An anti-Wnt-2 monoclonal antibody induces apoptosis in malignant melanoma cells and inhibits tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Statins inhibit reoxygenation-induced cardiomyocyte apoptosis: role for glycogen synthase kinase 3beta and transcription factor beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Increased glycolytic substrate protection improves ischemic cardiac dysfunction and reduces injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Beneficial effects of trimetazidine in ex vivo working ischemic hearts are due to a stimulation of glucose oxidation secondary to inhibition of long-chain 3-ketoacyl coenzyme a thiolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

High levels of fatty acids delay the recovery of intracellular pH and cardiac efficiency in post-ischemic hearts by inhibiting glucose oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Balancing contractility and energy production: the role of myocyte enhancer factor 2 (MEF2) in cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Increased glycogen synthase kinase-3 activity in diabetes- and obesity-prone C57BL/6J mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Inhibition of GSK-3 selectively reduces glucose-6-phosphatase and phosphatase and phosphoenolypyruvate carboxykinase gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

A role for the segment polarity gene shaggy/GSK-3 in the Drosophila circadian clock

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Circadian rhythms in cardiac gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Activated glycogen synthase-3 beta suppresses cardiac hypertrophy in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Stress-activated cytokines and the heart: from adaptation to maladaptation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Pharmacological inhibitors of glycogen synthase kinase 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

First non-ATP competitive glycogen synthase kinase 3 beta (GSK-3beta) inhibitors: thiadiazolidinones (TDZD) as potential drugs for the treatment of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

3-Anilino-4-arylmaleimides: potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

GSK-3-selective inhibitors derived from Tyrian purple indirubins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

The α-isoform of glycogen synthase kinase-3 from rabbit skeletal muscle is inactivated by p70 S6 kinase or MAP kinase-activated protein kinase-1 in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.9.3.447

21 January 2018

Identifiers

DOI

10.1517/14728222.9.3.447

1 reference

12 August 2017

1 reference