(Q36158931)

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Direct pharmacological monitoring of the developmental switch in NMDA receptor subunit composition using TCN 213, a GluN2A-selective, glycine-dependent antagonist

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22022974%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Direct pharmacological monitoring of the developmental switch in NMDA receptor subunit composition using TCN 213, a GluN2A-selective, glycine-dependent antagonist (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22022974%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Giles E. Hardingham

5

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15 January 2020

6

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15 January 2020

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S McKay

1

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15 January 2020

N H Griffiths

2

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15 January 2020

P A Butters

3

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15 January 2020

E B Thubron

4

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15 January 2020

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1 June 2012

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15 January 2020

British Journal of Pharmacology

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15 January 2020

166

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15 January 2020

3

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15 January 2020

924-937

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15 January 2020

Guide to Receptors and Channels (GRAC), 5th edition

1 reference

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2 October 2017

New advances in NMDA receptor pharmacology

1 reference

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2 October 2017

Identification and characterization of novel NMDA receptor antagonists selective for NR2A- over NR2B-containing receptors

1 reference

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2 October 2017

Glutamate receptor ion channels: structure, regulation, and function

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2 October 2017

A nomenclature for ligand-gated ion channels

1 reference

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2 October 2017

Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses

1 reference

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2 October 2017

Taking the time to study competitive antagonism

1 reference

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2 October 2017

Equilibrium constants for (R)-[(S)-1-(4-bromo-phenyl)-ethylamino]-(2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)-methyl]-phosphonic acid (NVP-AAM077) acting at recombinant NR1/NR2A and NR1/NR2B N-methyl-D-aspartate receptors: Implications for studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417419

2 October 2017

Pharmacological insights obtained from structure-function studies of ionotropic glutamate receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417419

2 October 2017

Structural features of the glutamate binding site in recombinant NR1/NR2A N-methyl-D-aspartate receptors determined by site-directed mutagenesis and molecular modeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417419

2 October 2017

Glutamate receptor gating.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417419

2 October 2017

Receptor compartmentalization and trafficking at glutamate synapses: a developmental proposal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417419

2 October 2017

Some quantitative uses of drug antagonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417419

2 October 2017

Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417419

2 October 2017

5-Phosphonomethylquinoxalinediones as competitive NMDA receptor antagonists with a preference for the human 1A/2A, rather than 1A/2B receptor composition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417419

2 October 2017

The incorporation of NMDA receptors with a distinct subunit composition at nascent hippocampal synapses in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417419

2 October 2017

Differentiation of glycine antagonist sites of N-methyl-D-aspartate receptor subtypes. Preferential interaction of CGP 61594 with NR1/2B receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417419

2 October 2017

Cloning and functional characterization of human heteromeric N-methyl-D-aspartate receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417419

2 October 2017

Changing subunit composition of heteromeric NMDA receptors during development of rat cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417419

2 October 2017

Developmental and regional expression in the rat brain and functional properties of four NMDA receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417419

2 October 2017

Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417419

2 October 2017

Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417419

2 October 2017

Heteromeric NMDA receptors: molecular and functional distinction of subtypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417419

2 October 2017

Triheteromeric NR1/NR2A/NR2B receptors constitute the major N-methyl-D-aspartate receptor population in adult hippocampal synapses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417419

2 July 2018

Developmental changes in NMDA receptor glycine affinity and ifenprodil sensitivity reveal three distinct populations of NMDA receptors in individual rat cortical neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417419

2 July 2018

Ro 25-6981, a highly potent and selective blocker of N-methyl-D-aspartate receptors containing the NR2B subunit. Characterization in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417419

2 July 2018

Molecular dissection of native mammalian forebrain NMDA receptors containing the NR1 C2 exon: direct demonstration of NMDA receptors comprising NR1, NR2A, and NR2B subunits within the same complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417419

2 July 2018

NMDA-receptor channel diversity in the developing cerebellum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417419

2 July 2018

Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417419

2 July 2018

Stimulation of Protein Tyrosine Phosphorylation by NMDA Receptor Activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417419

2 July 2018

Developmental regulation of NMDA receptor-mediated synaptic currents at a central synapse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417419

2 July 2018

Activity-dependent decrease in NMDA receptor responses during development of the visual cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417419

2 July 2018

NR2B- and NR2D-containing synaptic NMDA receptors in developing rat substantia nigra pars compacta dopaminergic neurones

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01748.X

21 January 2018

Modulation of glycine potency in rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01748.X

21 January 2018

A critical period for long-term potentiation at thalamocortical synapses

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01748.X

21 January 2018

Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-D-aspartate glutamate receptors.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01748.X

21 January 2018

Kainic acid-induced seizures produce necrotic, not apoptotic, neurons with internucleosomal DNA cleavage: implications for programmed cell death mechanisms.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01748.X

21 January 2018

Modulation of triheteromeric NMDA receptors by N-terminal domain ligands

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01748.X

21 January 2018

In developing hippocampal neurons, NR2B-containing N-methyl-D-aspartate receptors (NMDARs) can mediate signaling to neuronal survival and synaptic potentiation, as well as neuronal death

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01748.X

21 January 2018

Phenylethanolamines inhibit NMDA receptors by enhancing proton inhibition.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01748.X

21 January 2018

Quantification of the Mg2+-induced potency shift of amantadine and memantine voltage-dependent block in human recombinant GluN1/GluN2A NMDARs.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01748.X

21 January 2018

Specific targeting of pro-death NMDA receptor signals with differing reliance on the NR2B PDZ ligand

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01748.X

21 January 2018

Increased contribution of NR2A subunit to synaptic NMDA receptors in developing rat cortical neurons.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01748.X

21 January 2018

Mg2+ and memantine block of rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01748.X

21 January 2018

NR2A subunit expression shortens NMDA receptor synaptic currents in developing neocortex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3417419

23 September 2018

Glycine potentiates the NMDA response in cultured mouse brain neurons

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01748.X

21 January 2018

Long-Lasting NMDA Receptor-Mediated EPSCs in Mouse Striatal Medium Spiny Neurons

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2011.01748.X

21 January 2018

Coexpression of postsynaptic density-95 protein with NMDA receptors results in enhanced receptor expression together with a decreased sensitivity to L-glutamate

1 reference

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12 December 2020

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15 January 2020

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15 January 2020

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15 January 2020

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