(Q36163675)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27741240%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

title

Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate (English)

1 reference

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25 March 2020

5

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25 March 2020

Karen Lyons

6

1 reference

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25 March 2020

author name string

Weiguang Wang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27741240%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Buer Song

2

1 reference

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25 March 2020

Teni Anbarchian

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27741240%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

Anna Shirazyan

4

1 reference

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25 March 2020

publication date

14 October 2016

1 reference

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25 March 2020

1 reference

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25 March 2020

volume

12

1 reference

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25 March 2020

issue

10

1 reference

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25 March 2020

page(s)

e1006352

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27741240%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

25 March 2020

copyright license

start time

14 October 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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2 October 2017

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Smad7 regulates terminal maturation of chondrocytes in the growth plate

2 October 2017

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Deletion of the transforming growth factor β receptor type II gene in articular chondrocytes leads to a progressive osteoarthritis-like phenotype in mice

2 October 2017

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2 October 2017

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SnoN suppresses maturation of chondrocytes by mediating signal cross-talk between transforming growth factor-β and bone morphogenetic protein pathways

2 October 2017

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Master transcription factors determine cell-type-specific responses to TGF-β signaling

2 October 2017

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HEB and E2A function as SMAD/FOXH1 cofactors

2 October 2017

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Graded Nodal/Activin signaling titrates conversion of quantitative phospho-Smad2 levels into qualitative embryonic stem cell fate decisions

2 October 2017

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2 October 2017

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High throughput determination of TGFβ1/SMAD3 targets in A549 lung epithelial cells

2 October 2017

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Activin A expression regulates multipotency of mesenchymal progenitor cells

2 October 2017

1 reference

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Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription.

2 October 2017

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TGF-beta signaling in chondrocyte terminal differentiation and osteoarthritis: modulation and integration of signaling pathways through receptor-Smads

2 October 2017

1 reference

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BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation

2 October 2017

1 reference

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Non-Smad pathways in TGF-beta signaling

2 October 2017

1 reference

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Chromatin immunoprecipitation on microarray analysis of Smad2/3 binding sites reveals roles of ETS1 and TFAP2A in transforming growth factor beta signaling.

2 October 2017

1 reference

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Redundant roles of SMAD2 and SMAD3 in ovarian granulosa cells in vivo.

2 October 2017

1 reference

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TGF-beta signaling is essential for joint morphogenesis.

2 October 2017

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Indian Hedgehog produced by postnatal chondrocytes is essential for maintaining a growth plate and trabecular bone

2 October 2017

1 reference

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A tale of two proteins: differential roles and regulation of Smad2 and Smad3 in TGF-beta signaling

2 October 2017

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Transforming growth factor-beta stimulates cyclin D1 expression through activation of beta-catenin signaling in chondrocytes

2 October 2017

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Smad transcription factors

2 October 2017

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Mice exclusively expressing the short isoform of Smad2 develop normally and are viable and fertile.

2 October 2017

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TGF-beta signaling in chondrocytes

2 October 2017

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Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis

2 October 2017

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Conditional deletion of the TGF-beta type II receptor in Col2a expressing cells results in defects in the axial skeleton without alterations in chondrocyte differentiation or embryonic development of long bones

2 October 2017

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Multiple functions of BMPs in chondrogenesis

2 October 2017

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Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog

2 October 2017

1 reference

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Indian hedgehog gene is a target of the bone morphogenetic protein signaling pathway

2 October 2017

1 reference

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TGF-beta signaling in human skeletal and patterning disorders

2 October 2017

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Interaction with Smad4 is indispensable for suppression of BMP signaling by c-Ski

2 October 2017

1 reference

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Cell fate decisions within the mouse organizer are governed by graded Nodal signals

2 October 2017

1 reference

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Developmental regulation of the growth plate

2 October 2017

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2 October 2017

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Regulation of cell proliferation by Smad proteins

2 October 2017

1 reference

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Herbert Evans and the collecting of medicine and science.

2 October 2017

1 reference

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TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065210

TGF-beta/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065210

Ski represses bone morphogenic protein signaling in Xenopus and mammalian cells

2 October 2017

1 reference

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Functions of mammalian Smad genes as revealed by targeted gene disruption in mice

2 October 2017

1 reference

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SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065210

Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065210

Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065210

Indian hedgehog in the late-phase differentiation in mouse chondrogenic EC cells, ATDC5: upregulation of type X collagen and osteoprotegerin ligand mRNAs

2 October 2017

1 reference

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Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065210

Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065210

Human Smad3 and Smad4 are sequence-specific transcription activators

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065210

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065210

Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065210

Expression of a truncated, kinase-defective TGF-beta type II receptor in mouse skeletal tissue promotes terminal chondrocyte differentiation and osteoarthritis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065210

Smad2 and Smad3 cooperate and antagonize simultaneously in vertebrate neurogenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065210

Ski inhibits TGF-β/phospho-Smad3 signaling and accelerates hypertrophic differentiation in chondrocytes

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065210

Regulation of transcription factor Twist expression by the DNA architectural protein high mobility group A2 during epithelial-to-mesenchymal transition

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065210

Deletion of Tgfbr2 in Prx1-cre expressing mesenchyme results in defects in development of the long bones and joints

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065210

Expression of transforming growth factor-beta (TGFbeta) and the TGFbeta signalling molecule SMAD-2P in spontaneous and instability-induced osteoarthritis: role in cartilage degradation, chondrogenesis and osteophyte formation

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065210

Smad3 mutant mice develop metastatic colorectal cancer

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065210

Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-beta, activin, and bone morphogenetic protein-inducible enhancer

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065210

Protective effects of naringin against paraquat-induced acute lung injury and pulmonary fibrosis in mice

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065210

Promoter-wide analysis of Smad4 binding sites in human epithelial cells.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065210

Smad3-deficient chondrocytes have enhanced BMP signaling and accelerated differentiation

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065210

Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065210

Localization and Developmental Expression of the Activin Signal Transduction Proteins Smads 2, 3, and 4 in the Baboon Fetal Ovary1

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065210

Col2a1-directed expression of Cre recombinase in differentiating chondrocytes in transgenic mice.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065210

Transforming growth factor-beta stimulates articular chondrocyte cell growth through p44/42 MAP kinase (ERK) activation

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065210

Dual action of sonic hedgehog on chondrocyte hypertrophy: retrovirus mediated ectopic sonic hedgehog expression in limb bud micromass culture induces novel cartilage nodules that are positive for alkaline phosphatase and type X collagen

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5065210

[Expression of transforming growth factor beta 1 and conection tissue growth factor in ankylosing spondylitis]

23 September 2018

1 reference

12 December 2020

Localization of Smads, the TGF-beta family intracellular signaling components during endochondral ossification

1 reference

12 December 2020

Catastrophic antiphospholipid syndrome in a 14-year-old child

1 reference

12 December 2020

Concomitant and isolated expression of TGF-alpha and EGF-R in human hepatoma cells supports the hypothesis of autocrine, paracrine, and endocrine growth of human hepatoma

1 reference

12 December 2020

10.1371/JOURNAL.PGEN.1006352

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27741240%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27741240%20AND%20SRC:MED&resulttype=core&format=json

25 March 2020

PubMed publication ID

27741240

1 reference