(Q36164175)

English

Prolonged tenofovir treatment of macaques infected with K65R reverse transcriptase mutants of SIV results in the development of antiviral immune responses that control virus replication after drug withdrawal

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scholarly article

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Europe PubMed Central

PMC publication ID

12 August 2017

Prolonged tenofovir treatment of macaques infected with K65R reverse transcriptase mutants of SIV results in the development of antiviral immune responses that control virus replication after drug withdrawal (English)

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

1 reference

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inferred from title

David C. Montefiori

13

object named as

David Montefiori

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Europe PubMed Central

PMC publication ID

12 August 2017

11

object named as

Walid Heneine

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Donald N Forthal

12

object named as

Donald N Forthal

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

author name string

Koen K A Van Rompay

1

1 reference

Europe PubMed Central

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12 August 2017

Kristin A Trott

2

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Kartika Jayashankar

3

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Yongzhi Geng

4

1 reference

Europe PubMed Central

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12 August 2017

Celia C LaBranche

5

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Jeffrey A Johnson

6

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Gary Landucci

7

1 reference

Europe PubMed Central

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12 August 2017

Jonathan Lipscomb

8

1 reference

Europe PubMed Central

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12 August 2017

Ross P Tarara

9

1 reference

Europe PubMed Central

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12 August 2017

Don R Canfield

10

1 reference

Europe PubMed Central

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12 August 2017

Kristina Abel

14

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Europe PubMed Central

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12 August 2017

publication date

17 July 2012

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Europe PubMed Central

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12 August 2017

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Europe PubMed Central

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12 August 2017

9

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Europe PubMed Central

PMC publication ID

12 August 2017

57

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Europe PubMed Central

PMC publication ID

12 August 2017

copyright license

Creative Commons Attribution 2.0 Generic

17 July 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

1 reference

April 2022 Public Data File from Crossref

HIV persistence and the prospect of long-term drug-free remissions for HIV-infected individuals

1 reference

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1 reference

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International cohort analysis of the antiviral activities of zidovudine and tenofovir in the presence of the K65R mutation in reverse transcriptase

1 reference

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Immunogenicity of viral vector, prime-boost SIV vaccine regimens in infant rhesus macaques: attenuated vesicular stomatitis virus (VSV) and modified vaccinia Ankara (MVA) recombinant SIV vaccines compared to live-attenuated SIV.

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Tonsillar application of AT-2 SIV affords partial protection against rectal challenge with SIVmac239.

1 reference

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DNA vaccination in rhesus macaques induces potent immune responses and decreases acute and chronic viremia after SIVmac251 challenge

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Therapeutic immunization in HIV infection

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The challenge of finding a cure for HIV infection

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With minimal systemic T-cell expansion, CD8+ T Cells mediate protection of rhesus macaques immunized with attenuated simian-human immunodeficiency virus SHIV89.6 from vaginal challenge with simian immunodeficiency virus.

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A therapeutic SIV DNA vaccine elicits T-cell immune responses, but no sustained control of viremia in SIVmac239-infected rhesus macaques

1 reference

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Chronic administration of tenofovir to rhesus macaques from infancy through adulthood and pregnancy: summary of pharmacokinetics and biological and virological effects.

1 reference

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Longitudinal in vivo positron emission tomography imaging of infected and activated brain macrophages in a macaque model of human immunodeficiency virus encephalitis correlates with central and peripheral markers of encephalitis and areas of synapti

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Elite HIV controllers: myth or reality?

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Treatment interruption strategies: how great are the risks?

1 reference

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2 October 2017

Mamu-B*08-positive macaques control simian immunodeficiency virus replication

1 reference

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2 October 2017

Sequential emergence and clinical implications of viral mutants with K70E and K65R mutation in reverse transcriptase during prolonged tenofovir monotherapy in rhesus macaques with chronic RT-SHIV infection

1 reference

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2 October 2017

Administration of fludarabine-loaded autologous red blood cells in simian immunodeficiency virus-infected sooty mangabeys depletes pSTAT-1-expressing macrophages and delays the rebound of viremia after suspension of antiretroviral therapy

1 reference

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2 October 2017

Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade

1 reference

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2 October 2017

Rhesus macaque polyclonal and monoclonal antibodies inhibit simian immunodeficiency virus in the presence of human or autologous rhesus effector cells

1 reference

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PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

1 reference

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Structured treatment interruptions with tenofovir monotherapy for simian immunodeficiency virus-infected newborn macaques

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The high-frequency major histocompatibility complex class I allele Mamu-B*17 is associated with control of simian immunodeficiency virus SIVmac239 replication

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Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies

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Suppression of virus load by highly active antiretroviral therapy in rhesus macaques infected with a recombinant simian immunodeficiency virus containing reverse transcriptase from human immunodeficiency virus type 1.

1 reference

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CD8+-cell-mediated suppression of virulent simian immunodeficiency virus during tenofovir treatment

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Biological effects of short-term or prolonged administration of 9-[2-(phosphonomethoxy)propyl]adenine (tenofovir) to newborn and infant rhesus macaques

1 reference

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Highly uneven distribution of tenofovir-selected simian immunodeficiency virus in different anatomical sites of rhesus macaques

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Trafficking of human immunodeficiency virus type 1-specific CD8+ T cells to gut-associated lymphoid tissue during chronic infection

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1 reference

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1 reference

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1 reference

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1 reference

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2 October 2017

Early short-term 9-[2-(R)-(phosphonomethoxy)propyl]adenine treatment favorably alters the subsequent disease course in simian immunodeficiency virus-infected newborn Rhesus macaques.

1 reference

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9-[2-(Phosphonomethoxy)propyl]adenine therapy of established simian immunodeficiency virus infection in infant rhesus macaques

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1 reference

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1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-9-57

21 January 2018

The clinical benefits of tenofovir for simian immunodeficiency virus-infected macaques are larger than predicted by its effects on standard viral and immunologic parameters.

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-9-57

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Adoptive transfer of simian immunodeficiency virus (SIV) naïve autologous CD4(+) cells to macaques chronically infected with SIV is sufficient to induce long-term nonprogressor status

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-9-57

21 January 2018

Long-term follow-up of patients taking tenofovir DF with low-level HIV-1 viremia and the K65R substitution in HIV-1 RT.

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-9-57

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Patterns of resistance emerging in HIV-1 from antiretroviral-experienced patients undergoing intensification therapy with tenofovir disoproxil fumarate

1 reference

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An anti-HIV strategy combining chemotherapy and therapeutic vaccination

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-9-57

21 January 2018

Effects of monotherapy with (R)-9-(2-phosphonylmethoxypropyl)adenine (PMPA) on the evolution of a primary Simian immunodeficiency virus (SIV) isolate.

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-9-57

21 January 2018

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1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-9-57

21 January 2018

Toward HIV eradication or remission: the tasks ahead

1 reference

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21 January 2018

Rate of HIV-1 RNA rebound upon stopping antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-9-57

21 January 2018

Strong cell-mediated immune responses are associated with the maintenance of low-level viremia in antiretroviral-treated individuals with drug-resistant human immunodeficiency virus type 1.

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-9-57

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Antiviral activity of lamivudine in salvage therapy for multidrug-resistant HIV-1 infection

1 reference

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21 January 2018

Persistent antiretroviral activity of nucleoside analogues after prolonged zidovudine and lamivudine therapy as demonstrated by rapid loss of activity after discontinuation

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-9-57

21 January 2018

Interruption of treatment with individual therapeutic drug classes in adults with multidrug-resistant HIV-1 infection

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-9-57

21 January 2018

Tenofovir primes rhesus macaque cells in vitro for enhanced interleukin-12 secretion

1 reference

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Highly sensitive SIV plasma viral load assay: practical considerations, realistic performance expectations, and application to reverse engineering of vaccines for AIDS.

1 reference

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21 January 2018

Vaccination of macaques with long-standing SIVmac251 infection lowers the viral set point after cessation of antiretroviral therapy.

1 reference

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Persistent low viral load on antiretroviral therapy is associated with T cell-mediated control of HIV replication

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-9-57

21 January 2018

Short Communication: A Rapid and Sensitive Real-Time PCR Assay for the K65R Drug Resistance Mutation in SIV Reverse Transcriptase

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-9-57

21 January 2018

Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes

1 reference

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21 January 2018

Viremia control following antiretroviral treatment and therapeutic immunizationduring primary SIV251 infection of macaques

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-9-57

21 January 2018

Re-emergence of HIV after stopping therapy

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-9-57

21 January 2018

Acyclic nucleoside phosphonate antivirals activate gene expression of monocyte chemotactic protein 1 and 3

1 reference

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21 January 2018

Initiation of antiretroviral therapy during chronic SIV infection leads to rapid reduction in viral loads and the level of T-cell immune response

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intermittent episodes of detectable HIV viremia in patients receiving nonnucleoside reverse-transcriptase inhibitor-based or protease inhibitor-based highly active antiretroviral therapy regimens are equivalent in incidence and prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simian-human immunodeficiency virus SHIV89.6-induced protection against intravaginal challenge with pathogenic SIVmac239 is independent of the route of immunization and is associated with a combination of cytotoxic T-lymphocyte and alpha interferon

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA immunization in combination with effective antiretroviral drug therapy controls viral rebound and prevents simian AIDS after treatment is discontinued

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805180

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based on heuristic

inferred from PubMed ID database lookup

The emerging race to cure HIV infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805180

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based on heuristic

inferred from PubMed ID database lookup

Long-term immunovirologic control following antiretroviral therapy interruption in patients treated at the time of primary HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular typing of major histocompatibility complex class I alleles in the Indian rhesus macaque which restrict SIV CD8+ T cell epitopes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

It is safe to stop antiretroviral therapy in patients with preantiretroviral CD4 cell counts >250 cells/microL

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of (R)-9-(2-phosphonylmethoxypropyl)adenine monotherapy on chronic SIV infection in macaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805180

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1742-4690-9-57

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

ResearchGate publication ID

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