(Q36182171)

12 August 2017

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title

The influence of adenovirus fiber structure and function on vector development for gene therapy (English)

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12 August 2017

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Stuart A Nicklin

1

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author name string

Eugene Wu

series ordinal

2

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12 August 2017

Glen R Nemerow

series ordinal

3

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12 August 2017

Andrew H Baker

series ordinal

4

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12 August 2017

language of work or name

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1 September 2005

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12 August 2017

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12 August 2017

volume

12

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12 August 2017

issue

3

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12 August 2017

page(s)

384-393

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The structure of the human adenovirus 2 penton

12 August 2017

cites work

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7 January 2021

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Integrin alpha v beta 5 selectively promotes adenovirus mediated cell membrane permeabilization.

7 January 2021

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Stepwise dismantling of adenovirus 2 during entry into cells

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Adenovirus protein VI mediates membrane disruption following capsid disassembly.

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Integrin alpha(v)beta1 is an adenovirus coreceptor

7 January 2021

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Integrin alpha3beta1 is an alternative cellular receptor for adenovirus serotype 5

7 January 2021

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Liver-directed gene transfer in non-human primates

7 January 2021

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7 January 2021

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7 January 2021

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Simultaneous CAR- and alpha V integrin-binding ablation fails to reduce Ad5 liver tropism

7 January 2021

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In vivo hepatic adenoviral gene delivery occurs independently of the coxsackievirus-adenovirus receptor

7 January 2021

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CAR-binding ablation does not change biodistribution and toxicity of adenoviral vectors

7 January 2021

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CAR- or alphav integrin-binding ablated adenovirus vectors, but not fiber-modified vectors containing RGD peptide, do not change the systemic gene transfer properties in mice

7 January 2021

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Reducing the native tropism of adenovirus vectors requires removal of both CAR and integrin interactions

7 January 2021

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7 January 2021

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Coxsackie and adenovirus receptor binding ablation reduces adenovirus liver tropism and toxicity

7 January 2021

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Adenovirus fiber disrupts CAR-mediated intercellular adhesion allowing virus escape

7 January 2021

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Ablating CAR and integrin binding in adenovirus vectors reduces nontarget organ transduction and permits sustained bloodstream persistence following intraperitoneal administration

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Replication-deficient human adenovirus type 35 vectors for gene transfer and vaccination: efficient human cell infection and bypass of preexisting adenovirus immunity

7 January 2021

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Genetic manipulations of adenovirus type 5 fiber resulting in liver tropism attenuation

7 January 2021

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Reduction of natural adenovirus tropism to the liver by both ablation of fiber-coxsackievirus and adenovirus receptor interaction and use of replaceable short fiber

7 January 2021

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Subgroup B and F fiber chimeras eliminate normal adenovirus type 5 vector transduction in vitro and in vivo

7 January 2021

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Characterization of in vitro and in vivo gene transfer properties of adenovirus serotype 35 vector

7 January 2021

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Adenovirus vectors containing chimeric type 5 and type 35 fiber proteins exhibit altered and expanded tropism and increase the size limit of foreign genes

7 January 2021

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The human membrane cofactor CD46 is a receptor for species B adenovirus serotype 3

7 January 2021

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Adenovirus type 11 uses CD46 as a cellular receptor

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Adenovirus serotype 7 retention in a late endosomal compartment prior to cytosol escape is modulated by fiber protein

7 January 2021

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The interaction between the fiber knob domain and the cellular attachment receptor determines the intracellular trafficking route of adenoviruses

7 January 2021

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Membrane cofactor protein is a receptor for adenoviruses associated with epidemic keratoconjunctivitis

7 January 2021

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Adenovirus serotype 30 fiber does not mediate transduction via the coxsackie-adenovirus receptor

7 January 2021

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A 50-kDa membrane protein mediates sialic acid-independent binding and infection of conjunctival cells by adenovirus type 37.

7 January 2021

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7 January 2021

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7 January 2021

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The identification of an adenovirus receptor by using affinity capture and mass spectrometry.

7 January 2021

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Adenoviral serotype 5 vectors pseudotyped with fibers from subgroup D show modified tropism in vitro and in vivo.

7 January 2021

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Adenovirus Binding to Blood Factors Results in Liver Cell Infection and Hepatotoxicity

7 January 2021

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Targeting endothelial cells with adenovirus expressing nitric oxide synthase prevents elevation of blood pressure in stroke-prone spontaneously hypertensive rats

7 January 2021

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A targetable, injectable adenoviral vector for selective gene delivery to pulmonary endothelium in vivo

7 January 2021

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Combined transductional and transcriptional targeting improves the specificity of transgene expression in vivo

7 January 2021

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7 January 2021

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7 January 2021

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Generation of recombinant adenovirus vectors with modified fibers for altering viral tropism.

7 January 2021

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7 January 2021

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7 January 2021

A single amino acid in the adenovirus type 37 fiber confers binding to human conjunctival cells.

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7 January 2021

Upregulation of integrins alpha v beta 3 and alpha v beta 5 on human monocytes and T lymphocytes facilitates adenovirus-mediated gene delivery

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7 January 2021

Infectious entry pathway of adenovirus type 2.

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7 January 2021

Mutations in the DG loop of adenovirus type 5 fiber knob protein abolish high-affinity binding to its cellular receptor CAR.

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7 January 2021

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7 January 2021

Selective targeting of human cells by a chimeric adenovirus vector containing a modified fiber protein.

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7 January 2021

Fiber swap between adenovirus subgroups B and C alters intracellular trafficking of adenovirus gene transfer vectors.

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7 January 2021

Molecular characterization of hemagglutination domains on the fibers of subgenus D adenoviruses

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7 January 2021

10.1016/J.YMTHE.2005.05.008

Identifiers

DOI

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12 August 2017

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