(Q36182184)

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Asymmetric and Symmetric Dimethylarginine as Risk Markers for Total Mortality and Cardiovascular Outcomes: A Systematic Review and Meta-Analysis of Prospective Studies

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scholarly article

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Europe PubMed Central

12 August 2017

2 references

17 June 2019

19 November 2019

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Asymmetric and Symmetric Dimethylarginine as Risk Markers for Total Mortality and Cardiovascular Outcomes: A Systematic Review and Meta-Analysis of Prospective Studies (English)

1 reference

Europe PubMed Central

12 August 2017

cardiovascular disease

2 references

17 June 2019

19 November 2019

1 reference

19 November 2019

systematic review

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Sabrina Schlesinger

object named as

Sabrina Schlesinger

1

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author name string

Svenja R Sonntag

2

1 reference

Europe PubMed Central

12 August 2017

Wolfgang Lieb

3

1 reference

Europe PubMed Central

12 August 2017

Renke Maas

4

1 reference

Europe PubMed Central

12 August 2017

language of work or name

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publication date

3 November 2016

3 references

Europe PubMed Central

12 August 2017

17 June 2019

19 November 2019

3 references

Europe PubMed Central

12 August 2017

17 June 2019

19 November 2019

11

1 reference

Europe PubMed Central

12 August 2017

11

1 reference

Europe PubMed Central

12 August 2017

e0165811

1 reference

Europe PubMed Central

12 August 2017

copyright license

Creative Commons Attribution 4.0 International

2 references

Europe PubMed Central

17 June 2019

Europe PubMed Central

19 November 2019

copyright status

0 references

Biochemistry and regulation of the protein arginine methyltransferases (PRMTs).

1 reference

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1 October 2017

Asymmetric dimethylarginine and cardiovascular risk: systematic review and meta-analysis of 22 prospective studies

1 reference

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1 October 2017

Symmetric dimethylarginine as predictor of graft loss and all-cause mortality in renal transplant recipients

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1 October 2017

Asymmetric dimethylarginine, race, and mortality in hemodialysis patients

1 reference

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1 October 2017

Endothelial function in patients with familial Mediterranean fever-related amyloidosis and association with cardiovascular events

1 reference

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1 October 2017

Incidence of all-cause and cardiovascular mortality predicted by symmetric dimethylarginine in the population-based study of health in pomerania

1 reference

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1 October 2017

Biomarkers of inflammation, fibrosis, cardiac stretch and injury predict death but not renal replacement therapy at 1 year in a Canadian chronic kidney disease cohort

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1 October 2017

Pharmacology and clinical pharmacology of methylarginines used as inhibitors of nitric oxide synthases

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1 October 2017

Regulation and prognostic relevance of symmetric dimethylarginine serum concentrations in critical illness and sepsis

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1 October 2017

Asymmetric dimethylarginine predicts survival in the elderly

1 reference

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1 October 2017

Omega-3 Status and the Relationship between Plasma Asymmetric Dimethylarginine and Risk of Myocardial Infarction in Patients with Suspected Coronary Artery Disease

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1 October 2017

Circulating levels of dimethylarginines, chronic kidney disease and long-term clinical outcome in non-ST-elevation myocardial infarction.

1 reference

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1 October 2017

Asymmetric and symmetric dimethylarginine and risk of secondary cardiovascular disease events and mortality in patients with stable coronary heart disease: the KAROLA follow-up study

1 reference

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1 October 2017

Alanine-glyoxylate aminotransferase-2 metabolizes endogenous methylarginines, regulates NO, and controls blood pressure.

1 reference

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1 October 2017

Meta-analysis for linear and nonlinear dose-response relations: examples, an evaluation of approximations, and software

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1 October 2017

Dietary fibre, whole grains, and risk of colorectal cancer: systematic review and dose-response meta-analysis of prospective studies

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1 October 2017

Reference intervals for plasma L-arginine and the L-arginine:asymmetric dimethylarginine ratio in the Framingham Offspring Cohort

1 reference

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1 October 2017

Body mass index, abdominal fatness and pancreatic cancer risk: a systematic review and non-linear dose-response meta-analysis of prospective studies

1 reference

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1 October 2017

Plasma symmetric dimethylarginine reference limits from the Framingham offspring cohort

1 reference

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1 October 2017

Symmetric dimethylarginine as a proinflammatory agent in chronic kidney disease

1 reference

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1 October 2017

Production of free methylarginines via the proteasome and autophagy pathways in cultured cells

1 reference

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1 October 2017

The role of asymmetric and symmetric dimethylarginines in renal disease

1 reference

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1 October 2017

Asymmetric dimethylarginine, endothelial nitric oxide bioavailability and mortality in sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5094762

1 October 2017

Increased asymmetric dimethylarginine in severe falciparum malaria: association with impaired nitric oxide bioavailability and fatal outcome

1 reference

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1 October 2017

Dimethylarginine dimethylaminohydrolase overexpression ameliorates atherosclerosis in apolipoprotein E-deficient mice by lowering asymmetric dimethylarginine

1 reference

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1 October 2017

Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement

1 reference

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1 October 2017

Asymmetric dimethylarginine (ADMA) as a prospective marker of cardiovascular disease and mortality--an update on patient populations with a wide range of cardiovascular risk

1 reference

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1 October 2017

Targeted metabolomic evaluation of arginine methylation and cardiovascular risks: potential mechanisms beyond nitric oxide synthase inhibition

1 reference

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1 October 2017

Asymmetric dimethylarginine reference intervals determined with liquid chromatography-tandem mass spectrometry: results from the Framingham offspring cohort

1 reference

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1 October 2017

Asymmetric dimethylarginine and mortality in stages 3 to 4 chronic kidney disease

1 reference

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1 October 2017

Criteria for evaluation of novel markers of cardiovascular risk: a scientific statement from the American Heart Association

1 reference

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1 October 2017

Plasma asymmetric dimethylarginine and incidence of cardiovascular disease and death in the community

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5094762

1 October 2017

Differential effects of arginine methylation on diastolic dysfunction and disease progression in patients with chronic systolic heart failure

1 reference

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1 October 2017

Elevated plasma concentrations of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine predict adverse events in patients undergoing noncardiac surgery

1 reference

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1 October 2017

The pharmacodynamics of L-arginine

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1 October 2017

Asymmetric dimethylarginine, smoking, and risk of coronary heart disease in apparently healthy men: prospective analysis from the population-based Monitoring of Trends and Determinants in Cardiovascular Disease/Kooperative Gesundheitsforschung in de

1 reference

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1 October 2017

Disruption of methylarginine metabolism impairs vascular homeostasis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5094762

1 October 2017

Symmetric dimethylarginine (SDMA) as endogenous marker of renal function--a meta-analysis

1 reference

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1 October 2017

Biomarkers of cardiovascular disease: molecular basis and practical considerations

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1 October 2017

Quantification of ADMA: analytical approaches

1 reference

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1 October 2017

Pharmacotherapies and their influence on asymmetric dimethylargine (ADMA).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5094762

1 October 2017

Asymmetric dimethylarginine and the risk of cardiovascular events and death in patients with coronary artery disease: results from the AtheroGene Study

1 reference

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1 October 2017

Multiple-center, randomized, placebo-controlled, double-blind study of the nitric oxide synthase inhibitor 546C88: effect on survival in patients with septic shock

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1 October 2017

Association of fibrinogen, C-reactive protein, albumin, or leukocyte count with coronary heart disease: meta-analyses of prospective studies

1 reference

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1 October 2017

Methods for summarizing the risk associations of quantitative variables in epidemiologic studies in a consistent form

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1 October 2017

Methods for Trend Estimation from Summarized Dose-Response Data, with Applications to Meta-Analysis

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1 October 2017

The effects of endothelial dysfunction and inflammation on slow coronary flow

1 reference

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2 July 2018

Asymmetrical dimethylarginine is associated with renal and cardiovascular outcomes and all-cause mortality in renal transplant recipients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5094762

2 July 2018

Symmetric dimethylarginine predicts all-cause mortality following ischemic stroke

1 reference

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2 July 2018

Methylarginines and mortality in patients with end stage renal disease: a prospective cohort study.

1 reference

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2 July 2018

Metabolism of NG,NG-and NG,N'G-dimethylarginine in rats

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2 July 2018

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2 July 2018

Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure

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2 July 2018

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2 July 2018

Dimethylarginine dimethylaminohydrolase 2 regulates nitric oxide synthesis and hemodynamics and determines outcome in polymicrobial sepsis

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23 September 2018

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23 September 2018

Symmetrical dimethylarginine predicts mortality in the general population: observations from the Dallas heart study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5094762

23 September 2018

Elevated asymmetric dimethylarginine levels predict short- and long-term mortality risk in critically ill patients

1 reference

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23 September 2018

Transport of asymmetric dimethylarginine (ADMA) by cationic amino acid transporter 2 (CAT2), organic cation transporter 2 (OCT2) and multidrug and toxin extrusion protein 1 (MATE1).

1 reference

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23 September 2018

Endothelial dysfunction, inflammation and malnutrition markers as predictors of mortality in dialysis patients: multimarker approach.

1 reference

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23 September 2018

Abnormal high-density lipoprotein induces endothelial dysfunction via activation of Toll-like receptor-2.

1 reference

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23 September 2018

The L-Arginine-asymmetric dimethylarginine ratio is an independent predictor of mortality in dilated cardiomyopathy.

1 reference

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23 September 2018

Asymmetric dimethylarginine predicts clinical outcomes in ischemic chronic heart failure.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5094762

23 September 2018

Reduced renal plasma clearance does not explain increased plasma asymmetric dimethylarginine in hypertensive subjects with mild to moderate renal insufficiency.

1 reference

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23 September 2018

Imbalance of arginine and asymmetric dimethylarginine is associated with markers of circulatory failure, organ failure and mortality in shock patients.

1 reference

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23 September 2018

Plasma asymmetric dimethylarginine predicts death and major adverse cardiovascular events in individuals referred for coronary angiography.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5094762

23 September 2018

Circulating levels of asymmetric dimethylarginine are an independent risk factor for left ventricular hypertrophy and predict cardiovascular events in pre-dialysis patients with chronic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5094762

23 September 2018

A novel predictor of restenosis and adverse cardiac events: asymmetric dimethylarginine

1 reference

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23 September 2018

Relation of baseline plasma ADMA levels to cardiovascular morbidity and mortality at two years in men with diabetes mellitus referred for coronary angiography.

1 reference

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23 September 2018

Cardiorespiratory fitness as a quantitative predictor of all-cause mortality and cardiovascular events in healthy men and women: a meta-analysis

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23 September 2018

Relationship of baseline plasma ADMA levels to cardiovascular outcomes at 2 years in men with acute coronary syndrome referred for coronary angiography.

1 reference

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23 September 2018

Asymmetric and symmetric dimethylarginines are of similar predictive value for cardiovascular risk in the general population

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23 September 2018

Role of symmetric dimethylarginine in vascular damage by increasing ROS via store-operated calcium influx in monocytes

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23 September 2018

Asymmetric dimethylarginine independently predicts fatal and nonfatal myocardial infarction and stroke in women: 24-year follow-up of the population study of women in Gothenburg

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23 September 2018

Impact of asymmetric dimethylarginine on mortality after acute myocardial infarction

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5094762

23 September 2018

Plasma concentration of asymmetric dimethylarginine (ADMA) predicts cardiovascular morbidity and mortality in type 1 diabetic patients with diabetic nephropathy

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23 September 2018

Metabolic profiling of arginine and nitric oxide pathways predicts hemodynamic abnormalities and mortality in patients with cardiogenic shock after acute myocardial infarction

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23 September 2018

Asymmetrical (ADMA) and symmetrical dimethylarginine (SDMA) as potential risk factors for cardiovascular and renal outcome in chronic kidney disease - possible candidates for paradoxical epidemiology?

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5094762

23 September 2018

Symmetrical dimethylarginine: a new combined parameter for renal function and extent of coronary artery disease

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23 September 2018

L-arginine therapy in acute myocardial infarction: the Vascular Interaction With Age in Myocardial Infarction (VINTAGE MI) randomized clinical trial

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23 September 2018

Asymmetrical dimethylarginine plasma clearance persists after acute total nephrectomy in rats

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23 September 2018

Asymmetrical dimethylarginine predicts progression to dialysis and death in patients with chronic kidney disease: a competing risks modeling approach

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23 September 2018

Cardiovascular effects of systemic nitric oxide synthase inhibition with asymmetrical dimethylarginine in humans

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23 September 2018

Plasma levels of asymmetrical dimethylarginine and adverse cardiovascular events after percutaneous coronary intervention

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23 September 2018

Asymmetrical dimethylarginine (ADMA) in critically ill patients: high plasma ADMA concentration is an independent risk factor of ICU mortality.

1 reference

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23 September 2018

Risk of acute coronary events and serum concentration of asymmetrical dimethylarginine

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23 September 2018

Plasma concentration of asymmetrical dimethylarginine and mortality in patients with end-stage renal disease: a prospective study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5094762

23 September 2018

Inflammation and Asymmetric Dimethylarginine for Predicting Death and Cardiovascular Events in ESRD Patients

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21 January 2018

The inhibitory effect of simvastatin on the ADMA-induced inflammatory reaction is mediated by MAPK pathways in endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/27812151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Asymmetric dimethylarginine is increased in chronic thromboembolic pulmonary hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/27812151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of the cardiovascular risk marker asymmetric dimethylarginine (ADMA) with the human cationic amino acid transporter 1 (CAT1)

1 reference

https://pubmed.ncbi.nlm.nih.gov/27812151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum reference intervals of homoarginine, ADMA, and SDMA in the study of health in Pomerania

1 reference

https://pubmed.ncbi.nlm.nih.gov/27812151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma asymmetric dimethylarginine and mortality in patients with acute decompensation of chronic heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/27812151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Symmetrical and asymmetrical dimethylarginine as predictors for mortality in patients referred for coronary angiography: the Ludwigshafen Risk and Cardiovascular Health study

1 reference

https://pubmed.ncbi.nlm.nih.gov/27812151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Asymmetric dimethylarginine predicts major adverse cardiovascular events in patients with advanced peripheral artery disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/27812151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Asymmetric dimethylarginine as an independent risk marker for mortality in ambulatory patients with peripheral arterial disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/27812151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amino acid N-acetylation: metabolic elimination of symmetric dimethylarginine as symmetric N(α)-acetyldimethylarginine, determined in human plasma and urine by LC-MS/MS

1 reference

https://pubmed.ncbi.nlm.nih.gov/27812151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A stable-isotope based technique for the determination of dimethylarginine dimethylaminohydrolase (DDAH) activity in mouse tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/27812151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Asymmetric dimethylarginine and oxidative stress following coronary artery bypass grafting: associations with postoperative outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/27812151

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0165811

1 reference

Europe PubMed Central

12 August 2017

2016PLoSO..1165811S

0 references

1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

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