(Q36188828)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26489398%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

title

TORC2: a novel target for treating age-associated memory impairment (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26489398%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26489398%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Gregg Roman

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26489398%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

author name string

Wei Huang

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26489398%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

Mauro Costa-Mattioli

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26489398%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

language of work or name

English

0 references

publication date

22 October 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26489398%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26489398%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26489398%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

page(s)

15193

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26489398%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

27 February 2020

copyright license

start time

22 October 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4614817/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan

1 October 2017

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In vivo evidence for mTORC2-mediated actin cytoskeleton rearrangement in neurons

1 October 2017

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1 October 2017

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The actin cytoskeleton in memory formation

1 October 2017

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Molecular mechanism for age-related memory loss: the histone-binding protein RbAp48

1 October 2017

1 reference

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Impact of aging brain circuits on cognition

1 October 2017

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Ablation of the mTORC2 component rictor in brain or Purkinje cells affects size and neuron morphology

1 October 2017

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Activation of transposable elements during aging and neuronal decline in Drosophila

1 October 2017

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mTORC2 controls actin polymerization required for consolidation of long-term memory.

1 October 2017

1 reference

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mTOR is a key modulator of ageing and age-related disease

1 October 2017

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The global prevalence of dementia: a systematic review and metaanalysis

1 October 2017

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Synaptic distributions of GluA2 and PKMζ in the monkey dentate gyrus and their relationships with aging and memory

1 October 2017

1 reference

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Suppression of PKR promotes network excitability and enhanced cognition by interferon-γ-mediated disinhibition

1 October 2017

1 reference

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mTOR complex 2 signaling and functions

1 October 2017

1 reference

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Selective pharmacogenetic inhibition of mammalian target of Rapamycin complex I (mTORC1) blocks long-term synaptic plasticity and memory storage

1 October 2017

1 reference

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Between destiny and disease: genetics and molecular pathways of human central nervous system aging

1 October 2017

1 reference

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Neural Protein Synthesis during Aging: Effects on Plasticity and Memory

1 October 2017

1 reference

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Altered histone acetylation is associated with age-dependent memory impairment in mice.

1 October 2017

1 reference

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The molecular and cellular biology of enhanced cognition

1 October 2017

1 reference

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RTP801 is induced in Parkinson's disease and mediates neuron death by inhibiting Akt phosphorylation/activation

1 October 2017

1 reference

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The adaptive brain: aging and neurocognitive scaffolding

1 October 2017

1 reference

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Upregulation of calcium/calmodulin-dependent protein kinase IV improves memory formation and rescues memory loss with aging

1 October 2017

1 reference

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Actin in action: the interplay between the actin cytoskeleton and synaptic efficacy

1 October 2017

1 reference

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Defining the role of mTOR in cancer

1 October 2017

1 reference

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Akt inhibitor A-443654 induces rapid Akt Ser-473 phosphorylation independent of mTORC1 inhibition

1 October 2017

1 reference

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1 October 2017

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LTP consolidation: substrates, explanatory power, and functional significance

1 October 2017

1 reference

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TOR signaling in growth and metabolism

1 October 2017

1 reference

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Neural plasticity in the ageing brain

1 October 2017

1 reference

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Potent and selective inhibitors of Akt kinases slow the progress of tumors in vivo

1 October 2017

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

1 October 2017

1 reference

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Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

1 October 2017

1 reference

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Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

1 October 2017

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The emotional brain, fear, and the amygdala

1 October 2017

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World population beyond six billion.

1 October 2017

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Drosophila models of human neurodegenerative disease

1 October 2017

1 reference

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Induction of a dominant negative CREB transgene specifically blocks long-term memory in Drosophila

1 October 2017

1 reference

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Age-dependent alterations in hippocampal synaptic plasticity: relation to memory disorders

1 October 2017

1 reference

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Progressive dendritic changes in aging human cortex

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614817

Re-evaluating AKT regulation: role of TOR complex 2 in tissue growth

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614817

Layer-specific dendritic regression of pyramidal cells with ageing in the human prefrontal cortex

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614817

Genetic dissection of consolidated memory in Drosophila.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614817

Aging and its differential effects on consolidated memory forms in Drosophila

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614817

G(o) signaling is required for Drosophila associative learning.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614817

Activation of Akt/PKB, increased phosphorylation of Akt substrates and loss and altered distribution of Akt and PTEN are features of Alzheimer's disease pathology

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614817

The IGF-1/Akt pathway is neuroprotective in Huntington's disease and involves Huntingtin phosphorylation by Akt.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614817

A role for the PI-3 kinase signaling pathway in fear conditioning and synaptic plasticity in the amygdala

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614817

Effects of age on tissues and regions of the cerebrum and cerebellum.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614817

Jasplakinolide, a cytotoxic natural product, induces actin polymerization and competitively inhibits the binding of phalloidin to F-actin.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614817

Classical conditioning and retention in normal and mutantDrosophila melanogaster

22 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSREP15193

Involvement of hippocampal synaptic plasticity in age-related memory decline

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26489398

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SREP15193

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26489398%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26489398%20AND%20SRC:MED&resulttype=core&format=json

27 February 2020

PubMed publication ID

26489398

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26489398%20AND%20SRC:MED&resulttype=core&format=json