(Q36193418)

12 August 2017

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title

Receptors that mediate cellular dependence (English)

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12 August 2017

Bredesen DE

1

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12 August 2017

Mehlen P

series ordinal

2

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12 August 2017

Rabizadeh S

series ordinal

3

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12 August 2017

1 August 2005

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Cell Death & Differentiation

12 August 2017

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12 August 2017

12

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12 August 2017

1031-1043

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12 August 2017

8

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https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401680

12 August 2017

0 references

cites work

Disruption of epithelial cell-matrix interactions induces apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

p75NTR and the concept of cellular dependence: seeing how the other half die.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

p75NTR and apoptosis: Trk-dependent and Trk-independent effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Kennedy's disease: caspase cleavage of the androgen receptor is a crucial event in cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

The RET proto-oncogene induces apoptosis: a novel mechanism for Hirschsprung disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Netrin-1 acts as a survival factor via its receptors UNC5H and DCC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

The dependence receptor DCC (deleted in colorectal cancer) defines an alternative mechanism for caspase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Apoptosis and dependence receptors: a molecular basis for cellular addiction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

The dependence receptor hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Caspases: intracellular signaling by proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

DCC: linking tumor suppressor genes and altered cell surface interactions in cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

DCC: is there a connection between tumorigenesis and cell guidance molecules?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Suppression of tumorigenicity in human colon carcinoma cells by introduction of normal chromosome 5 or 18

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Altered phenotype of HT29 colonic adenocarcinoma cells following expression of the DCC gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Suppressed tumorigenicity of human endometrial cancer cells by the restored expression of the DCC gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Role of the dependence receptor DCC in colorectal cancer pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Netrin-1 controls colorectal tumorigenesis by regulating apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

cDCC (chicken homologue to a gene deleted in colorectal carcinoma) is an epithelial adhesion molecule expressed in the basal cells and involved in epithelial-mesenchymal interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

The molecular biology of axon guidance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Deleted in Colorectal Cancer (DCC) encodes a netrin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Binding of DCC by netrin-1 to mediate axon guidance independent of adenosine A2B receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Mediation of the DCC apoptotic signal by DIP13 alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Netrin-1-mediated axon outgrowth and cAMP production requires interaction with adenosine A2b receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

A ligand-gated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin-induced growth cone attraction to repulsion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

RGM and its receptor neogenin regulate neuronal survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Identification and characterization of neogenin, a DCC-related gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

UNC5H1 induces apoptosis via its juxtamembrane region through an interaction with NRAGE

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

p53RDL1 regulates p53-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

ret transforming gene encodes a fusion protein homologous to tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Neurturin, a relative of glial-cell-line-derived neurotrophic factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

TrnR2, a novel receptor that mediates neurturin and GDNF signaling through Ret.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Renal agenesis and the absence of enteric neurons in mice lacking GDNF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

GFRalpha1 is an essential receptor component for GDNF in the developing nervous system and kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

An epidermal growth factor receptor/ret chimera generates mitogenic and transforming signals: evidence for a ret-specific signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Identification of Shc docking site on Ret tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Mutations of the RET proto-oncogene in Hirschsprung's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Inhibition of neuroepithelial patched-induced apoptosis by sonic hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Gene transfer and molecular cloning of the rat nerve growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

p75LNGFR regulates Trk signal transduction and NGF-induced neuronal differentiation in MAH cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Expression of CD40 induces neural apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Apoptosis mediated by the TNF-related cytokine and receptor families

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Synthetic NGF peptide derivatives prevent neuronal death via a p75 receptor-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Neurotrophin dependence mediated by p75NTR: contrast between rescue by BDNF and NGF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

A comparison of the cytoplasmic domains of the Fas receptor and the p75 neurotrophin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

NADE, a p75NTR-associated cell death executor, is involved in signal transduction mediated by the common neurotrophin receptor p75NTR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

TRAF family proteins interact with the common neurotrophin receptor and modulate apoptosis induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

The zinc finger protein NRIF interacts with the neurotrophin receptor p75(NTR) and participates in programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Sortilin is essential for proNGF-induced neuronal cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Ten years on: mediation of cell death by the common neurotrophin receptor p75(NTR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

P75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

The CAG repeat within the androgen receptor gene and its relationship to prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Elevated levels of the alpha 5 beta 1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

A second cytotoxic proteolytic peptide derived from amyloid beta-protein precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Involvement of caspases in proteolytic cleavage of Alzheimer's amyloid-beta precursor protein and amyloidogenic A beta peptide formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Expression of mutant amyloid precursor proteins decreases adhesion and delays differentiation of Hep-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Amyloid beta protein toxicity mediated by the formation of amyloid-beta protein precursor complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Some morphometric aspects of the brain in senile dementia of the alzheimer type

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Immunohistochemical quantification of the synapse-related protein synaptophysin in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Extension of long leading processes and neuronal migration in the mammalian brain directed by the chemoattractant netrin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

The GDNF family ligands and receptors - implications for neural development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Discussion point. The case for floor plate induction by the notochord.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

The morphogen sonic hedgehog is an axonal chemoattractant that collaborates with netrin-1 in midline axon guidance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

A p75(NTR) and Nogo receptor complex mediates repulsive signaling by myelin-associated glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Growth-cone attraction to netrin-1 is converted to repulsion by laminin-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

A conserved interaction between beta1 integrin/PAT-3 and Nck-interacting kinase/MIG-15 that mediates commissural axon navigation in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Substrate cleavage by caspases generates protein fragments with Smac/Diablo-like activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

The dependence receptor UNC5H2 mediates apoptosis through DAP-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Chopper, a New Death Domain of the p75 Neurotrophin Receptor That Mediates Rapid Neuronal Cell Death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Induction of cell death by endogenous nerve growth factor through its p75 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

7 January 2021

Induction of apoptosis by the low-affinity NGF receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

7 January 2021

Is p75NGFR involved in developmental neural cell death?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

7 January 2021

The p75 nerve growth factor receptor mediates survival or death depending on the stage of sensory neuron development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

7 January 2021

The low-affinity nerve growth factor receptor p75NGFR mediates death of PC12 cells after nerve growth factor withdrawal

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

7 January 2021

The protooncogene bcl-2 inhibits apoptosis in PC12 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

7 January 2021

Identification of a chromosome 18q gene that is altered in colorectal cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

7 January 2021

Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

7 January 2021

The DCC gene product in cellular differentiation and colorectal tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

7 January 2021

Axon guidance to and from choice points.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

7 January 2021

Cadherin cell adhesion receptors as a morphogenetic regulator

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

7 January 2021

RET alternate splicing influences the interaction of activated RET with the SH2 and PTB domains of Shc, and the SH2 domain of Grb2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

7 January 2021

Neurotrophin dependence domain: a domain required for the mediation of apoptosis by the p75 neurotrophin receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

7 January 2021

Gene transfer and molecular cloning of the human NGF receptor.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

7 January 2021

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

7 January 2021

Absence of p75NTR causes increased basal forebrain cholinergic neuron size, choline acetyltransferase activity, and target innervation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

7 January 2021

Complete deletion of the neurotrophin receptor p75NTR leads to long-lasting increases in the number of basal forebrain cholinergic neurons.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

7 January 2021

Dimerization-dependent block of the proapoptotic effect of p75(NTR)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

7 January 2021

PLAIDD, a type II death domain protein that interacts with p75 neurotrophin receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

7 January 2021

Proteolytic processing of the p75 neurotrophin receptor and two homologs generates C-terminal fragments with signaling capability.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

7 January 2021

beta-Amyloid precursor protein binds to the neurite-promoting IKVAV site of laminin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

7 January 2021

Inherited neurodegenerative disorders caused by CAG/polyglutamine tract expansions: symposium introduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

7 January 2021

Various mechanisms cause RET-mediated signaling defects in Hirschsprung's disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401680

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401680

1 reference

release_irj2335hfjhztfig7qbv26jvhm

12 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/irj2335hfjhztfig7qbv26jvhm

24 November 2022

mapped directly with Wikidata item

1 reference