(Q36201760)

English

Acidosis promotes Bcl-2 family-mediated evasion of apoptosis: involvement of acid-sensing G protein-coupled receptor Gpr65 signaling to Mek/Erk

scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Acidosis promotes Bcl-2 family-mediated evasion of apoptosis: involvement of acid-sensing G protein-coupled receptor Gpr65 signaling to Mek/Erk (English)

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

G protein-coupled receptor

0 references

apoptotic process

1 reference

based on heuristic

inferred from title

author name string

Christopher Ryder

1

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Karen McColl

2

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Fei Zhong

3

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Clark W Distelhorst

4

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

language of work or name

0 references

publication date

8 June 2012

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

number of pages

13

1 reference

based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

287

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

33

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

27863-27875

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3431637/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Activation of GPR4 by acidosis increases endothelial cell adhesion through the cAMP/Epac pathway

1 reference

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The novel Bcl-2 inhibitor ABT-737 is more effective in hypoxia and is able to reverse hypoxia-induced drug resistance in neuroblastoma cells

1 reference

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1 October 2017

Apoptosis induced by overall metabolic stress converges on the Bcl-2 family proteins Noxa and Mcl-1

1 reference

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1 October 2017

Phosphorylation of Puma modulates its apoptotic function by regulating protein stability

1 reference

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1 October 2017

Glucocorticoid-mediated repression of the oncogenic microRNA cluster miR-17~92 contributes to the induction of Bim and initiation of apoptosis

1 reference

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1 October 2017

Akt requires glucose metabolism to suppress puma expression and prevent apoptosis of leukemic T cells

1 reference

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1 October 2017

Manipulating tumor acidification as a cancer treatment strategy

1 reference

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1 October 2017

Post-transcriptional and post-translational regulation of Bcl2.

1 reference

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1 October 2017

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1 reference

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1 October 2017

pH control mechanisms of tumor survival and growth

1 reference

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1 October 2017

The G protein-coupled receptor T-cell death-associated gene 8 (TDAG8) facilitates tumor development by serving as an extracellular pH sensor

1 reference

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1 October 2017

Mechanism of regulation of bcl-2 mRNA by nucleolin and A+U-rich element-binding factor 1 (AUF1)

1 reference

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1 October 2017

Glutamine addiction: a new therapeutic target in cancer

1 reference

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1 October 2017

Blockade of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase and murine double minute synergistically induces Apoptosis in acute myeloid leukemia via BH3-only proteins Puma and Bim.

1 reference

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1 October 2017

The BCL-2 family reunion

1 reference

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zeta-Crystallin is a bcl-2 mRNA binding protein involved in bcl-2 overexpression in T-cell acute lymphocytic leukemia

1 reference

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1 October 2017

Rethinking the Warburg effect with Myc micromanaging glutamine metabolism

1 reference

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1 October 2017

Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer

1 reference

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1 October 2017

PUMA, a potent killer with or without p53

1 reference

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Eosinophil viability is increased by acidic pH in a cAMP- and GPR65-dependent manner

1 reference

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1 October 2017

Acidic preconditioning protects endothelial cells against apoptosis through p38- and Akt-dependent Bcl-xL overexpression.

1 reference

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Tumour cell survival signalling by the ERK1/2 pathway

1 reference

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Bcl-2 inhibitors: small molecules with a big impact on cancer therapy

1 reference

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Pharmacological PKA inhibition: all may not be what it seems

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1 reference

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Relations between the mitogen-activated protein kinase and the cAMP-dependent protein kinase pathways: comradeship and hostility

1 reference

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Impact of hypoxic and acidic extracellular conditions on cytotoxicity of chemotherapeutic drugs

1 reference

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1 October 2017

Apoptosis induction in human melanoma cells by inhibition of MEK is caspase-independent and mediated by the Bcl-2 family members PUMA, Bim, and Mcl-1.

1 reference

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1 October 2017

Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells.

1 reference

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1 October 2017

Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members

1 reference

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Impact of extracellular acidity on the activity of P-glycoprotein and the cytotoxicity of chemotherapeutic drugs

1 reference

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Tumor acidity, chemoresistance and proton pump inhibitors.

1 reference

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Normal immune development and glucocorticoid-induced thymocyte apoptosis in mice deficient for the T-cell death-associated gene 8 receptor.

1 reference

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Overexpression of G protein-coupled receptors in cancer cells: involvement in tumor progression

1 reference

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1 October 2017

Stressing out over survival: glutamine as an apoptotic modulator.

1 reference

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Spatial heterogeneity and oxygen dependence of glucose consumption in R3230Ac and fibrosarcomas of the Fischer 344 rat.

1 reference

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Differential proton sensitivity of related G protein-coupled receptors T cell death-associated gene 8 and G2A expressed in immune cells

1 reference

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Identification of T cell death-associated gene 8 (TDAG8) as a novel acid sensing G-protein-coupled receptor

1 reference

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Why do cancers have high aerobic glycolysis?

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1 October 2017

The glucocorticoid-induced gene tdag8 encodes a pro-apoptotic G protein-coupled receptor whose activation promotes glucocorticoid-induced apoptosis

1 reference

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Inhibition of the Raf-MEK1/2-ERK1/2 signaling pathway, Bcl-xL down-regulation, and chemosensitization of non-Hodgkin's lymphoma B cells by Rituximab.

1 reference

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TDAG8 is a proton-sensing and psychosine-sensitive G-protein-coupled receptor

1 reference

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Bcl-2 functionally interacts with inositol 1,4,5-trisphosphate receptors to regulate calcium release from the ER in response to inositol 1,4,5-trisphosphate.

1 reference

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G protein-coupled receptors GPR4 and TDAG8 are oncogenic and overexpressed in human cancers

1 reference

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Control of T cell viability

1 reference

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Identification of nucleolin as an AU-rich element binding protein involved in bcl-2 mRNA stabilization

1 reference

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Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3.

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Cell-cycle arrest by PD184352 requires inhibition of extracellular signal-regulated kinases (ERK) 1/2 but not ERK5/BMK1.

1 reference

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pH and therapy of human cancers.

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1 reference

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The Hallmarks of Cancer

1 reference

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1 reference

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Acid-sensing by the T cell death-associated gene 8 (TDAG8) receptor cloned from rat brain

1 reference

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1 reference

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Modulation of growth and radiochemosensitivity of human malignant glioma cells by acidosis

1 reference

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1 reference

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22 September 2018

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1 reference

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22685289

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22685289

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.384685

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

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