(Q36212145)

9 January 2018

title

Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's Disease (English)

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9 January 2018

Pernilla Wittung-Stafshede

0 references

1 reference

15

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PubMed publication ID

12 August 2017

16

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PubMed publication ID

12 August 2017

10

Viviana Gradinaru

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Stefan Janssen

object named as

Stefan Janssen

Marie-Françoise Chesselet

4

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11

object named as

Marie-Francoise Chesselet

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9 January 2018

12

Ali Keshavarzian

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9 January 2018

Rosa Krajmalnik-Brown

14

object named as

Rosa Krajmalnik-Brown

1 reference

9 January 2018

author name string

Timothy R Sampson

1

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9 January 2018

Justine W Debelius

2

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9 January 2018

Taren Thron

3

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9 January 2018

Gauri G Shastri

5

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9 January 2018

Zehra Esra Ilhan

6

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9 January 2018

Collin Challis

7

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9 January 2018

Catherine E Schretter

8

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9 January 2018

Sandra Rocha

9

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9 January 2018

Kathleen M Shannon

13

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9 January 2018

Sarkis K Mazmanian

17

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9 January 2018

language of work or name

English

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publication date

1 December 2016

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9 January 2018

published in

Cell

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9 January 2018

volume

167

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9 January 2018

issue

6

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9 January 2018

page(s)

1469-1480.e12

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9 January 2018

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5718049/fullTextXML

inferred from PubMed Central ID database lookup

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29 June 2018

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Host microbiota constantly control maturation and function of microglia in the CNS.

29 June 2018

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29 June 2018

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Gut microbiota are related to Parkinson's disease and clinical phenotype

29 June 2018

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29 June 2018

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Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats

29 June 2018

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29 June 2018

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29 June 2018

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29 June 2018

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Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease

29 June 2018

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29 June 2018

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29 June 2018

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29 June 2018

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29 June 2018

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29 June 2018

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Genetic and microbial factors modulating the ubiquitin proteasome system in inflammatory bowel disease

29 June 2018

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29 June 2018

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The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis

29 June 2018

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Neuroimmunological processes in Parkinson's disease and their relation to α-synuclein: microglia as the referee between neuronal processes and peripheral immunity

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia

29 June 2018

1 reference

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Effects of minocycline on spatial learning, hippocampal neurogenesis and microglia in aged and adult mice

29 June 2018

1 reference

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Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice

29 June 2018

1 reference

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SortMeRNA: fast and accurate filtering of ribosomal RNAs in metatranscriptomic data.

29 June 2018

1 reference

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Mice overexpressing wild-type human alpha-synuclein display alterations in colonic myenteric ganglia and defecation

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

Interactions between the microbiota and the immune system

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

A progressive mouse model of Parkinson's disease: the Thy1-aSyn ("Line 61") mice

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

An improved Greengenes taxonomy with explicit ranks for ecological and evolutionary analyses of bacteria and archaea

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

The intestinal microbiota affect central levels of brain-derived neurotropic factor and behavior in mice

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

Fatty acid transport protein expression in human brain and potential role in fatty acid transport across human brain microvessel endothelial cells

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

Normal gut microbiota modulates brain development and behavior

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

Neuroinflammation and α-synuclein dysfunction potentiate each other, driving chronic progression of neurodegeneration in a mouse model of Parkinson's disease.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

QIIME allows analysis of high-throughput community sequencing data

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

A critical evaluation of the Braak staging scheme for Parkinson's disease.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

Molecular mechanisms of L-DOPA-induced dyskinesia

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

Ecological and evolutionary forces shaping microbial diversity in the human intestine

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

UniFrac: a new phylogenetic method for comparing microbial communities

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

Postnatal microbial colonization programs the hypothalamic-pituitary-adrenal system for stress response in mice

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

Idiopathic Parkinson's disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

Therapeutic strategies for human amyloid diseases

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

Differential neuropathological alterations in transgenic mice expressing alpha-synuclein from the platelet-derived growth factor and Thy-1 promoters

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

Substantial production of dopamine in the human gastrointestinal tract

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

Microglia development follows a stepwise program to regulate brain homeostasis.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

Colonic inflammation in Parkinson's disease.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

Reduced anxiety-like behavior and central neurochemical change in germ-free mice.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

Patient-reported autonomic symptoms in Parkinson disease

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

Clinical and biochemical correlates of insoluble alpha-synuclein in dementia with Lewy bodies.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

Early and progressive sensorimotor anomalies in mice overexpressing wild-type human alpha-synuclein.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

Tumor necrosis factor-alpha (TNF-alpha) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5718049

Short chain fatty acids and gut microbiota differ between patients with Parkinson's disease and age-matched controls

22 September 2018

1 reference

12 December 2020

alpha-Synuclein membrane interactions and lipid specificity

1 reference

12 December 2020

Is alpha-synuclein in the colon a biomarker for premotor Parkinson's disease? Evidence from 3 cases

1 reference

12 December 2020

A not entirely benign procedure: progression of Parkinson's disease

1 reference

12 December 2020

Interleukin-1 beta, interleukin-6, epidermal growth factor and transforming growth factor-alpha are elevated in the brain from parkinsonian patients

1 reference

12 December 2020

10.1016/J.CELL.2016.11.018

Identifiers

DOI

1 reference

9 January 2018

PMC publication ID

5718049

1 reference

9 January 2018

PubMed publication ID

27912057

1 reference

9 January 2018