(Q36216352)

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Swedish Alzheimer mutation induces mitochondrial dysfunction mediated by HSP60 mislocalization of amyloid precursor protein (APP) and beta-amyloid

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Swedish Alzheimer mutation induces mitochondrial dysfunction mediated by HSP60 mislocalization of amyloid precursor protein (APP) and beta-amyloid (English)

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Alzheimer's disease

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Mathew Blurton-Jones

object named as

Mathew Blurton-Jones

7

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author name string

Ken Carlson Walls

1

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Pinar Coskun

2

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Jose Luis Gallegos-Perez

3

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Nineli Zadourian

4

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Kristine Freude

5

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Suhail Rasool

6

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Kim Nicholas Green

8

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Frank Michael LaFerla

9

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Europe PubMed Central

PMC publication ID

12 August 2017

language of work or name

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publication date

29 June 2012

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Europe PubMed Central

PMC publication ID

12 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

12 August 2017

287

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Europe PubMed Central

PMC publication ID

12 August 2017

36

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

30317-30327

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3436283/fullTextXML

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inferred from PubMed Central ID database lookup

Mitochondrial dysfunction and accumulation of the β-secretase-cleaved C-terminal fragment of APP in Alzheimer's disease transgenic mice

1 reference

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A mitochondrial etiology of Alzheimer and Parkinson disease

1 reference

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Intraneuronal APP, not free Aβ peptides in 3xTg-AD mice: implications for tau versus Aβ-mediated Alzheimer neurodegeneration

1 reference

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Soluble amyloid precursor protein induces rapid neural differentiation of human embryonic stem cells.

1 reference

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Lysosome dysfunction triggers Atg7-dependent neural apoptosis

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bcl-2/Adenovirus E1B 19-kd interacting protein 3 (BNIP3) regulates hypoxia-induced neural precursor cell death

1 reference

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Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice

1 reference

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Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease

1 reference

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Amyloid precursor protein, heat-shock proteins, and Bcl-2 form a complex in mitochondria and modulate mitochondria function and apoptosis in N2a cells.

1 reference

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Subcellular localization and dimerization of APLP1 are strikingly different from APP and APLP2.

1 reference

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Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

1 reference

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Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

1 reference

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Unusual cellular disposition of the mitochondrial molecular chaperones Hsp60, Hsp70 and Hsp10.

1 reference

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Pathogenesis of Alzheimer's disease

1 reference

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Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers

1 reference

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Cytosolic accumulation of HSP60 during apoptosis with or without apparent mitochondrial release: evidence that its pro-apoptotic or pro-survival functions involve differential interactions with caspase-3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436283

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Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436283

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Differential effects of mitochondrial heat shock protein 60 and related molecular chaperones to prevent intracellular beta-amyloid-induced inhibition of complex IV and limit apoptosis

1 reference

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Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

1 reference

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Inactivation of the mitochondrial heat shock protein zim17 leads to aggregation of matrix hsp70s followed by pleiotropic effects on morphology and protein biogenesis.

1 reference

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Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria

1 reference

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Mitochondria dysfunction of Alzheimer's disease cybrids enhances Abeta toxicity

1 reference

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Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

1 reference

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Chaperones increase association of tau protein with microtubules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436283

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Mitochondria in Alzheimer's disease

1 reference

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Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity

1 reference

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Inherent abnormalities in energy metabolism in Alzheimer disease. Interaction with cerebrovascular compromise

1 reference

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Hsp60 accelerates the maturation of pro-caspase-3 by upstream activator proteases during apoptosis

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1 reference

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Mitochondria, molecular chaperone proteins and the in vivo assembly of microtubules

1 reference

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Multipotent neural cell lines can engraft and participate in development of mouse cerebellum

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ABAD enhances Abeta-induced cell stress via mitochondrial dysfunction

1 reference

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Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease

1 reference

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21 January 2018

Proteomic and functional alterations in brain mitochondria from Tg2576 mice occur before amyloid plaque deposition.

1 reference

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Proteomic identification of a stress protein, mortalin/mthsp70/GRP75: relevance to Parkinson disease.

1 reference

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Unusual Cellular Disposition of the Mitochondrial Molecular Chaperones Hsp60, Hsp70 and Hsp10

1 reference

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1 reference

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Are mitochondria critical in the pathogenesis of Alzheimer's disease?

1 reference

https://pubmed.ncbi.nlm.nih.gov/22753410

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.365890

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

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