(Q34562025)

English

Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction.

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675337&resulttype=core&format=json

11 May 2020

Alzheimer's disease

0 references

1 reference

based on heuristic

inferred from title

author name string

Latha Devi

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675337&resulttype=core&format=json

11 May 2020

Badanavalu M Prabhu

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675337&resulttype=core&format=json

11 May 2020

Domenico F Galati

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675337&resulttype=core&format=json

11 May 2020

Narayan G Avadhani

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675337&resulttype=core&format=json

11 May 2020

Hindupur K Anandatheerthavarada

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675337&resulttype=core&format=json

11 May 2020

language of work or name

0 references

publication date

1 August 2006

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675337&resulttype=core&format=json

11 May 2020

26

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675337&resulttype=core&format=json

11 May 2020

35

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675337&resulttype=core&format=json

11 May 2020

9057-9068

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675337&resulttype=core&format=json

11 May 2020

The cholinergic hypothesis of Alzheimer's disease: a review of progress

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostate apoptosis response-4 production in synaptic compartments following apoptotic and excitotoxic insults: evidence for a pivotal role in mitochondrial dysfunction and neuronal degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Translating cell biology into therapeutic advances in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The TIM17.23 preprotein translocase of mitochondria: composition and function in protein transport into the matrix

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual targeting of cytochrome P4502B1 to endoplasmic reticulum and mitochondria involves a novel signal activation by cyclic AMP-dependent phosphorylation at ser128.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue variant effects of heme inhibitors on the mouse cytochrome c oxidase gene expression and catalytic activity of the enzyme complex.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A selective defect of cytochrome c oxidase is present in brain of Alzheimer disease patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial damage in Alzheimer's disease varies with apolipoprotein E genotype.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of learning on cytochrome oxidase activity in cuttlefish brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of apolipoprotein E (apoE) isoforms, beta-amyloid (Abeta) and apoE/Abeta complexes on protein kinase C-alpha (PKC-alpha) translocation and amyloid precursor protein (APP) processing in human SH-SY5Y neuroblastoma cells and fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial abnormalities in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of chronic sodium azide on brain and muscle cytochrome oxidase activity: a potential model to investigate environmental contributions to neurodegenerative diseases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Energy hypometabolism in posterior cingulate cortex of Alzheimer's patients: superficial laminar cytochrome oxidase associated with disease duration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transport of proteins into mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered metabolism of the amyloid beta precursor protein is associated with mitochondrial dysfunction in Down's syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E: a major piece in the Alzheimer's disease puzzle.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the human heart mitochondrial proteome

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation enhances mitochondrial targeting of GSTA4-4 through increased affinity for binding to cytoplasmic Hsp70.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E binding to low density lipoprotein receptor-related protein-1 inhibits cell migration via activation of cAMP-dependent protein kinase A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamatergic systems in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of metals in neurodegenerative processes: aluminum, manganese, and zinc.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein measurement with the Folin phenol reagent

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential expression of oxidative phosphorylation genes in patients with Alzheimer's disease: implications for early mitochondrial dysfunction and oxidative damage.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular genetics of late-onset Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitrogen disruption of synaptoneurosomes: an alternative method to isolate brain mitochondria.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphological characterization of Thioflavin-S-positive amyloid plaques in transgenic Alzheimer mice and effect of passive Abeta immunotherapy on their clearance

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta-induced changes in nitric oxide production and mitochondrial activity lead to apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shaping the mitochondrial proteome

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial failures in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presenilin function and gamma-secretase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single translation--dual destination: mechanisms of dual protein targeting in eukaryotes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease: interactions between cholinergic functions and beta-amyloid

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraneuronal Abeta accumulation and origin of plaques in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondria take center stage in aging and neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Are mitochondria critical in the pathogenesis of Alzheimer's disease?

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase A-mediated phosphorylation modulates cytochrome c oxidase function and augments hypoxia and myocardial ischemia-related injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome oxidase deficiency in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metals and trace elements in plasma and cerebrospinal fluid in normal aging and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blue native electrophoresis for isolation of membrane protein complexes in enzymatically active form

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential involvement of protein kinase C isozymes in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain aluminum in aging and Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The beta A4 amyloid precursor protein binding to copper.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional brain effects of sodium azide treatment on cytochrome oxidase activity: a quantitative histochemical study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased regional brain concentrations of ceruloplasmin in neurodegenerative disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Energy metabolism, oxidative stress and neuronal degeneration in Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C activity and protein levels in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Tim core complex defines the number of mitochondrial translocation contact sites and can hold arrested preproteins in the absence of matrix Hsp70-Tim44.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Consensus recommendations for the postmortem diagnosis of Alzheimer's disease. The National Institute on Aging, and Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer's Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting of NH2-terminal-processed microsomal protein to mitochondria: a novel pathway for the biogenesis of hepatic mitochondrial P450MT2

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant genes in familial Alzheimer's disease and transgenic models

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Copper, iron and zinc in Alzheimer's disease senile plaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/16943564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.1469-06.2006

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675337&resulttype=core&format=json

11 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675337&resulttype=core&format=json

11 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6675337&resulttype=core&format=json

11 May 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q34562025&oldid=1397868701"