(Q36216463)

English

Fas-associated factor 1 is a scaffold protein that promotes β-transducin repeat-containing protein (β-TrCP)-mediated β-catenin ubiquitination and degradation

scientific article

In more languages

default values for all languages

No label defined

No description defined

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Fas-associated factor 1 is a scaffold protein that promotes β-transducin repeat-containing protein (β-TrCP)-mediated β-catenin ubiquitination and degradation (English)

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

protein ubiquitination

1 reference

based on heuristic

inferred from title

author name string

Long Zhang

1

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Fangfang Zhou

2

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Yihao Li

3

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Yvette Drabsch

4

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Juan Zhang

5

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Hans van Dam

6

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Peter ten Dijke

7

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

language of work or name

0 references

publication date

22 June 2012

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

287

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

36

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

30701-30710

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Bisindoylmaleimide I enhances osteogenic differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Wnt/β-catenin signaling changes C2C12 myoblast proliferation and differentiation by inducing Id3 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Ubiquitin-specific protease 4 mitigates Toll-like/interleukin-1 receptor signaling and regulates innate immune activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

APP and APLP1 are degraded through autophagy in response to proteasome inhibition in neuronal cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Fas-associated factor 1 antagonizes Wnt signaling by promoting β-catenin degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Epithelial-mesenchymal transition in cancer: parallels between normal development and tumor progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Expression analysis of E-cadherin, Slug and GSK3beta in invasive ductal carcinoma of breast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Wnt/beta-catenin signaling: components, mechanisms, and diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

FAS-associated factor 1 (FAF1): diverse functions and implications for oncogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Activated TNF-alpha/NF-kappaB signaling via down-regulation of Fas-associated factor 1 in asbestos-induced mesotheliomas from Arf knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Uniparental disomies, homozygous deletions, amplifications, and target genes in mantle cell lymphoma revealed by integrative high-resolution whole-genome profiling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Stromal gene expression predicts clinical outcome in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

The association of GSK3 beta with E2F1 facilitates nerve growth factor-induced neural cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Fas-associated factor (FAF1) is required for the early cleavage-stages of mouse embryo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

FAF1 suppresses IkappaB kinase (IKK) activation by disrupting the IKK complex assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Beta-catenin/LEF-1 signalling in breast cancer--central players activated by a plethora of inputs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Microarray comparative genomic hybridization detection of chromosomal imbalances in uterine cervix carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Wnt signalling in stem cells and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Human Fas-associated factor 1, interacting with ubiquitinated proteins and valosin-containing protein, is involved in the ubiquitin-proteasome pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Irradiation specifically sensitises solid tumour cell lines to TRAIL mediated apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Stabilization of beta-catenin in the mouse zygote leads to premature epithelial-mesenchymal transition in the epiblast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

The Wnt signaling pathway in development and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Zebrafish Dpr2 inhibits mesoderm induction by promoting degradation of nodal receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

WNT and beta-catenin signalling: diseases and therapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

The transforming activity of Wnt effectors correlates with their ability to induce the accumulation of mammary progenitor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Convergence of Wnt, beta-catenin, and cadherin pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Wnt signaling and breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Fas-associated Factor-1 Inhibits Nuclear Factor-κB (NF-κB) Activity by Interfering with Nuclear Translocation of the RelA (p65) Subunit of NF-κB

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Dissecting the roles of beta-catenin and cyclin D1 during mammary development and neoplasia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

The pro-apoptotic FAS-associated factor 1 is specifically reduced in human gastric carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Requirement of the co-repressor homeodomain-interacting protein kinase 2 for ski-mediated inhibition of bone morphogenetic protein-induced transcriptional activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Fas-associated factor 1, FAF1, is a member of Fas death-inducing signaling complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with beta-catenin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

The molecular interaction of Fas and FAP-1. A tripeptide blocker of human Fas interaction with FAP-1 promotes Fas-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Functional interaction of beta-catenin with the transcription factor LEF-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

A Fas-associated protein factor, FAF1, potentiates Fas-mediated apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

1 October 2017

Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

29 June 2018

pangolin encodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.353524

21 January 2018

Targeted activation of beta-catenin signaling in basal mammary epithelial cells affects mammary development and leads to hyperplasia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.353524

21 January 2018

RNF12 controls embryonic stem cell fate and morphogenesis in zebrafish embryos by targeting Smad7 for degradation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.353524

21 January 2018

The APP intracellular domain (AICD) inhibits Wnt signalling and promotes neurite outgrowth.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.353524

21 January 2018

Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.353524

21 January 2018

Transactivation of vimentin by beta-catenin in human breast cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

22 September 2018

Characterization of novel nuclear targeting and apoptosis-inducing domains in FAS associated factor 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436314

22 September 2018

LEF-1 activates the transcription of E2F1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.353524

21 January 2018

Concomitant expression of epithelial-mesenchymal transition biomarkers in breast ductal carcinoma: association with progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/22730322

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wnt/β-catenin signal pathway stabilizes APP intracellular domain (AICD) and promotes its transcriptional activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22730322

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contact printing a biomimetic catecholic monolayer on a variety of surfaces and derivation reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/22730322

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.353524

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q36216463&oldid=1979020894"