(Q36218438)

12 August 2017

Alcohol steatosis and cytotoxicity: the role of cytochrome P4502E1 and autophagy (English)

1 reference

12 August 2017

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Defeng Wu

1

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12 August 2017

Xiaodong Wang

2

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12 August 2017

Richard Zhou

3

1 reference

12 August 2017

Lili Yang

4

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12 August 2017

Arthur I Cederbaum

5

1 reference

12 August 2017

20 July 2012

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Free Radical Biology and Medicine

12 August 2017

1 reference

12 August 2017

53

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12 August 2017

6

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12 August 2017

1346-1357

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describes a project that uses

12 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3436962/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Rapamycin as an antiaging therapeutic?: targeting mammalian target of rapamycin to treat Hutchinson-Gilford progeria and neurodegenerative diseases

29 June 2018

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Involvement of autophagy in alcoholic liver injury and hepatitis C pathogenesis

29 June 2018

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Functions of autophagy in hepatic and pancreatic physiology and disease

29 June 2018

1 reference

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The emerging role of autophagy in alcoholic liver disease.

29 June 2018

1 reference

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Autophagy in nonalcoholic steatohepatitis

29 June 2018

1 reference

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Regulation of lipid droplets by autophagy

29 June 2018

1 reference

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Ethanol enhances susceptibility to apoptotic cell death via down-regulation of autophagy-related proteins

29 June 2018

1 reference

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Cellular and mitochondrial effects of alcohol consumption

29 June 2018

1 reference

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Alcoholic steatohepatitis

29 June 2018

1 reference

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CYP2E1 enhances ethanol-induced lipid accumulation but impairs autophagy in HepG2 E47 cells

29 June 2018

1 reference

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Autophagy signaling through reactive oxygen species.

29 June 2018

1 reference

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Mechanisms and cell signaling in alcoholic liver disease

29 June 2018

1 reference

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Autophagy in liver diseases.

29 June 2018

1 reference

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Regulation of autophagy by ROS: physiology and pathology

29 June 2018

1 reference

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Chronic alcohol-induced liver injury and oxidant stress are decreased in cytochrome P4502E1 knockout mice and restored in humanized cytochrome P4502E1 knock-in mice

29 June 2018

1 reference

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Autophagy reduces acute ethanol-induced hepatotoxicity and steatosis in mice.

29 June 2018

1 reference

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Macroautophagy and chaperone-mediated autophagy are required for hepatocyte resistance to oxidant stress

29 June 2018

1 reference

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Autophagy in health and disease. 2. Regulation of lipid metabolism and storage by autophagy: pathophysiological implications

29 June 2018

1 reference

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mTOR regulation of autophagy

29 June 2018

1 reference

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Nrf2 and antioxidant defense against CYP2E1 toxicity

29 June 2018

1 reference

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Impaired autolysosome formation correlates with Lamp-2 depletion: role of apoptosis, autophagy, and necrosis in pancreatitis

29 June 2018

1 reference

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Autophagy and ethanol-induced liver injury

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436962

Effect of ethanol on hydrogen peroxide-induced AMPK phosphorylation

29 June 2018

1 reference

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29 June 2018

Autophagy in the liver

1 reference

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Development and properties of HepG2 cells that constitutively express CYP2E1.

29 June 2018

1 reference

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CYP2E1 and oxidative liver injury by alcohol

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436962

ROS, mitochondria and the regulation of autophagy

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436962

PTPs versus PTKs: the redox side of the coin

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436962

Eating oneself and uninvited guests: autophagy-related pathways in cellular defense

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436962

Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436962

Autophagy in health and disease: a double-edged sword

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436962

Oxidative stress, toxicology, and pharmacology of CYP2E1.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436962

Oxidants and antioxidants in alcohol-induced liver disease

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436962

Induction of catalase, alpha, and microsomal glutathione S-transferase in CYP2E1 overexpressing HepG2 cells and protection against short-term oxidative stress.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436962

Autophagy as a regulated pathway of cellular degradation

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436962

Cytochrome P-4502E1: its physiological and pathological role

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436962

Bioactivation of halogenated hydrocarbons by cytochrome P4502E1.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436962

Markedly enhanced cytochrome P450 2E1 induction and lipid peroxidation is associated with severe liver injury in fish oil-ethanol-fed rats

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436962

Oxidative and reductive metabolism by cytochrome P450 2E1.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436962

Role of cytochrome P-450 2E1 in ethanol-, carbon tetrachloride- and iron-dependent microsomal lipid peroxidation

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436962

Ethanol and liver: recent advances in the mechanisms of ethanol-induced hepatosteatosis.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436962

Cytochrome P450 2E1 contributes to ethanol-induced fatty liver in mice

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436962

Nrf2 is increased by CYP2E1 in rodent liver and HepG2 cells and protects against oxidative stress caused by CYP2E1.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436962

Insulin signaling in the transcriptional and posttranscriptional regulation of CYP2E1 expression

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436962

Inhibition of ethanol-induced liver disease in the intragastric feeding rat model by chlormethiazole

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436962

Reactive Oxygen Species Regulate Autophagy through Redox-Sensitive Proteases

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436962

Modulation of experimental alcohol-induced liver disease by cytochrome P450 2E1 inhibitors

21 October 2018

1 reference

12 December 2020

Ethanol consumption reduces the proteolytic capacity and protease activities of hepatic lysosomes

1 reference

12 December 2020

Ethanol-inducible cytochrome P450 (CYP2E1): biochemistry, molecular biology and clinical relevance: 1996 update

1 reference

12 December 2020

Lipid peroxidation, CYP2E1 and arachidonic acid metabolism in alcoholic liver disease in rats

1 reference

12 December 2020

Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis

1 reference

12 December 2020

Pathways of liver injury in alcoholic liver disease

1 reference

12 December 2020

10.1016/J.FREERADBIOMED.2012.07.005

Identifiers

DOI

1 reference

release_z2pparvnkzcuxos5r5k3irpr4y

12 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/z2pparvnkzcuxos5r5k3irpr4y

24 November 2022

mapped directly with Wikidata item

1 reference

12 August 2017

PubMed publication ID

22819980

1 reference