(Q36228978)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17846149%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

High basal STAT4 balanced by STAT1 induction to control type 1 interferon effects in natural killer cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17846149%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

author name string

Xin Wang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17846149%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Jennifer Louten

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17846149%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Wen-Ming Chu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17846149%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Christine A Biron

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17846149%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

language of work or name

English

0 references

publication date

10 September 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17846149%20AND%20SRC:MED&resulttype=core&format=json

Journal of Experimental Medicine

7 January 2020

published in

1 reference

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7 January 2020

volume

204

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17846149%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17846149%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

page(s)

2383-2396

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17846149%20AND%20SRC:MED&resulttype=core&format=json

SOCS proteins, cytokine signalling and immune regulation

7 January 2020

cites work

1 reference

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1 October 2017

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Modulation of STAT1 protein levels: a mechanism shaping CD8 T-cell responses in vivo

1 October 2017

1 reference

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Mechanisms of type-I- and type-II-interferon-mediated signalling

1 October 2017

1 reference

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DNA-PKcs, but not TLR9, is required for activation of Akt by CpG-DNA.

1 October 2017

1 reference

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The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response

1 October 2017

1 reference

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Dysregulated Sonic hedgehog signaling and medulloblastoma consequent to IFN-alpha-stimulated STAT2-independent production of IFN-gamma in the brain

1 October 2017

1 reference

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Epidermal growth factor receptor is a cellular receptor for human cytomegalovirus

1 October 2017

1 reference

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Dendritic cell responses to early murine cytomegalovirus infection: subset functional specialization and differential regulation by interferon alpha/beta

1 October 2017

1 reference

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Review: IFN-alpha/beta receptor interactions to biologic outcomes: understanding the circuitry

1 October 2017

1 reference

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Stats: transcriptional control and biological impact

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Biology and pathogenesis of lymphocytic choriomeningitis virus infection.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Promotion of alpha/beta interferon induction during in vivo viral infection through alpha/beta interferon receptor/STAT1 system-dependent and -independent pathways

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Stat1-dependent and -independent pathways in IFN-gamma-dependent signaling

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Interferon alpha/beta and interleukin 12 responses to viral infections: pathways regulating dendritic cell cytokine expression in vivo

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Biologic consequences of Stat1-independent IFN signaling.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Natural killer cells in antiviral defense: function and regulation by innate cytokines

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arrays

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

How cells respond to interferons

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Early murine cytomegalovirus (MCMV) infection induces liver natural killer (NK) cell inflammation and protection through macrophage inflammatory protein 1alpha (MIP-1alpha)-dependent pathways

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Interferon-alpha/beta inhibition of interleukin 12 and interferon-gamma production in vitro and endogenously during viral infection

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Activation of STAT4 by IL-12 and IFN-alpha: evidence for the involvement of ligand-induced tyrosine and serine phosphorylation.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN-alpha signals

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Phosphorylated interferon-alpha receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of the 113 kDa STAT2 protein

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

The molecular cell biology of interferon-gamma and its receptor

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Interferon gamma receptor deficient mice are resistant to endotoxic shock

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Functional role of type I and type II interferons in antiviral defense

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Interleukin 12, interferon gamma, and tumor necrosis factor alpha are the key cytokines of the generalized Shwartzman reaction

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Antiviral defense in mice lacking both alpha/beta and gamma interferon receptors

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Requirement for natural killer cell-produced interferon gamma in defense against murine cytomegalovirus infection and enhancement of this defense pathway by interleukin 12 administration

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Detection of intracellular phosphorylated STAT-4 by flow cytometry

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Cross talk of the interferon-alpha/beta signalling complex with gp130 for effective interleukin-6 signalling

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Stat4 regulates multiple components of IFN-gamma-inducing signaling pathways

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Stat4 is expressed in activated peripheral blood monocytes, dendritic cells, and macrophages at sites of Th1-mediated inflammation

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Anti-interferon-gamma antibody protects mice against the generalized Shwartzman reaction

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

The role of IFN-gamma in the pathology of experimental endotoxemia.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Type 1 IFN deficiency in the absence of normal splenic architecture during lymphocytic choriomeningitis virus infection

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Suppressor of cytokine signaling 1 regulates the immune response to infection by a unique inhibition of type I interferon activity

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

A critical function for type I interferons in cancer immunoediting

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Alternative activation of STAT1 and STAT3 in response to interferon-gamma

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Cutting edge: a murine, IL-12-independent pathway of IFN-gamma induction by gram-negative bacteria based on STAT4 activation by Type I IFN and IL-18 signaling

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Distinct requirements for IFNs and STAT1 in NK cell function

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Compartmental differences in NK cell responsiveness to IL-12 during lymphocytic choriomeningitis virus infection

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

The role of Stat4 in species-specific regulation of Th cell development by type I IFNs.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118450

Blocking Monoclonal Antibodies Specific for Mouse IFN-α/β Receptor Subunit 1 (IFNAR-1) from Mice Immunized by In Vivo Hydrodynamic Transfection

22 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20070401

Dendritic-cell maturation alters intracellular signaling networks, enabling differential effects of IFN- / on antigen cross-presentation

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.20070401

An absolute and restricted requirement for IL-12 in natural killer cell IFN-gamma production and antiviral defense. Studies of natural killer and T cell responses in contrasting viral infections

21 January 2018

1 reference

12 December 2020

Immune response in Stat2 knockout mice

1 reference

12 December 2020

Interferon alpha/beta-mediated inhibition and promotion of interferon gamma: STAT1 resolves a paradox

1 reference

12 December 2020

Critical role for STAT4 activation by type 1 interferons in the interferon-gamma response to viral infection

1 reference

12 December 2020

Coordinated and distinct roles for IFN-alpha beta, IL-12, and IL-15 regulation of NK cell responses to viral infection

1 reference

12 December 2020

A unique mechanism for innate cytokine promotion of T cell responses to viral infections

1 reference

12 December 2020

Evidence for IFN-gamma as a mediator of the lethality of endotoxin and tumor necrosis factor-alpha

1 reference

12 December 2020

Coordinate analysis of murine immune cell surface markers and intracellular phosphoproteins by flow cytometry

1 reference

12 December 2020

Distinct characteristics of murine STAT4 activation in response to IL-12 and IFN-alpha

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20070401

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17846149%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17846149%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

PubMed publication ID

17846149

1 reference