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Role of the LAT adaptor in T-cell development and Th2 differentiation
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
16102570
retrieved
12 August 2017
review article
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stated in
Europe PubMed Central
title
Role of the LAT adaptor in T-cell development and Th2 differentiation
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
16102570
retrieved
12 August 2017
author
Enrique Aguado
object named as
Enrique Aguado
series ordinal
2
0 references
Marie Malissen
object named as
Marie Malissen
series ordinal
3
0 references
Bernard Malissen
object named as
Bernard Malissen
series ordinal
1
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publication date
1 January 2005
1 reference
stated in
Europe PubMed Central
PubMed ID
16102570
retrieved
12 August 2017
published in
Advances in Immunology
1 reference
stated in
Europe PubMed Central
PubMed ID
16102570
retrieved
12 August 2017
volume
87
1 reference
stated in
Europe PubMed Central
PubMed ID
16102570
retrieved
12 August 2017
page(s)
1-25
1 reference
stated in
Europe PubMed Central
PubMed ID
16102570
retrieved
12 August 2017
cites work
Induction of T helper type 2 immunity by a point mutation in the LAT adaptor
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CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity
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Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: dependency on antigen dose and differential toll-like receptor ligation
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Non-T cell activation linker (NTAL): a transmembrane adaptor protein involved in immunoreceptor signaling
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T cell receptor ligation induces the formation of dynamically regulated signaling assemblies
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Inactivation of c-Cbl reverses neonatal lethality and T cell developmental arrest of SLP-76-deficient mice
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Structural basis for differential recognition of tyrosine-phosphorylated sites in the linker for activation of T cells (LAT) by the adaptor Gads
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Natively unfolded domains in endocytosis: hooks, lines and linkers.
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T cell receptor specificity is critical for the development of epidermal gammadelta T cells
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7 January 2021
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LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway
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Crossref
reference URL
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7 January 2021
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T helper cell differentiation: on again, off again
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7 January 2021
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Synergistic assembly of linker for activation of T cells signaling protein complexes in T cell plasma membrane domains
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Transcription: tantalizing times for T cells
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7 January 2021
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Binding specificity of multiprotein signaling complexes is determined by both cooperative interactions and affinity preferences
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Linker for activation of B cells: a functional equivalent of a mutant linker for activation of T cells deficient in phospholipase C-gamma1 binding
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LAB: a new membrane-associated adaptor molecule in B cell activation
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Adaptors as central mediators of signal transduction in immune cells
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Role of TCR-induced extracellular signal-regulated kinase activation in the regulation of early IL-4 expression in naive CD4+ T cells
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Transmembrane adapters: structure, biochemistry and biology
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Progressive differentiation and selection of the fittest in the immune response
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7 January 2021
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T cell development in TCR beta enhancer-deleted mice: implications for alpha beta T cell lineage commitment and differentiation.
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Identification of the minimal tyrosine residues required for linker for activation of T cell function
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
The single positive T cells found in CD3-zeta/eta-/- mice overtly react with self-major histocompatibility complex molecules upon restoration of normal surface density of T cell receptor-CD3 complex
1 reference
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Crossref
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7 January 2021
based on heuristic
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Function of the CD3 subunits of the pre-TCR and TCR complexes during T cell development.
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Negative feedback loop in T-cell activation through MAPK-catalyzed threonine phosphorylation of LAT.
1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
The lineage decisions of helper T cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
LAT regulates gammadelta T cell homeostasis and differentiation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Appearance of the LAT protein at an early stage of B-cell development and its possible role
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Intrathymic delta selection events in gammadelta cell development.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mapping the Zap-70 phosphorylation sites on LAT (linker for activation of T cells) required for recruitment and activation of signalling proteins in T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Ontogenic development and tissue distribution of V gamma 1-expressing gamma/delta T lymphocytes in normal mice
1 reference
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Crossref
reference URL
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7 January 2021
based on heuristic
inferred from DOI database lookup
Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
RasGRP1 transduces low-grade TCR signals which are critical for T cell development, homeostasis, and differentiation.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitory function of two NFAT family members in lymphoid homeostasis and Th2 development.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
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7 January 2021
based on heuristic
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Autosomal recessive hyperimmunoglobulin E syndrome: a distinct disease entity
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
CD28, Ox-40, LFA-1, and CD4 modulation of Th1/Th2 differentiation is directly dependent on the dose of antigen.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
The impact of duration versus extent of TCR occupancy on T cell activation: a revision of the kinetic proofreading model
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Knock-in mutation of the distal four tyrosines of linker for activation of T cells blocks murine T cell development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A LAT mutation that inhibits T cell development yet induces lymphoproliferation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
LAT links the pre-BCR to calcium signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dynamic changes in the mobility of LAT in aggregated lipid rafts upon T cell activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Innate and adaptive immunity: specificities and signaling hierarchies revisited
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Thymic selection revisited: how essential is it?
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Signaling life and death in the thymus: timing is everything
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Unexpectedly late expression of intracellular CD3epsilon and TCR gammadelta proteins during adult thymus development
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a phospholipase C-gamma1 (PLC-gamma1) SH3 domain-binding site in SLP-76 required for T-cell receptor-mediated activation of PLC-gamma1 and NFAT
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gads/Grb2-mediated association with LAT is critical for the inhibitory function of Gab2 in T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential role of LAT in T cell development
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Minimal requirement of tyrosine residues of linker for activation of T cells in TCR signaling and thymocyte development.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cutting Edge: Localization of linker for activation of T cells to lipid rafts is not essential in T cell activation and development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0065-2776%2805%2987001-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0065-2776(05)87001-4
1 reference
stated in
Europe PubMed Central
PubMed ID
16102570
retrieved
12 August 2017
PubMed ID
16102570
1 reference
stated in
Europe PubMed Central
PubMed ID
16102570
retrieved
12 August 2017
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