(Q36237868)

13 August 2017

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title

The therapeutic potential of RNA interference (English)

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13 August 2017

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Susan L Uprichard

1

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13 August 2017

language of work or name

English

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publication date

15 August 2005

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13 August 2017

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13 August 2017

volume

579

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13 August 2017

issue

26

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13 August 2017

page(s)

5996-6007

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Antisense technologies. Improvement through novel chemical modifications

13 August 2017

cites work

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21 January 2018

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RNA interference is mediated by 21- and 22-nucleotide RNAs

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A virus-encoded inhibitor that blocks RNA interference in mammalian cells

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Evidence that HIV-1 encodes an siRNA and a suppressor of RNA silencing.

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Expanding roles for miRNAs and siRNAs in cell regulation

21 January 2018

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MicroRNAs and the regulation of cell death

21 January 2018

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The functions of animal microRNAs

21 January 2018

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Stable suppression of tumorigenicity by virus-mediated RNA interference

21 January 2018

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Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

21 January 2018

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Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis

21 January 2018

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Allele-specific silencing of dominant disease genes

21 January 2018

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Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi).

21 January 2018

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Oligonucleotide‐Based Knockdown Technologies: Antisense Versus RNA Interference

21 January 2018

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Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo.

21 January 2018

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Comparison of the Suppressive Effects of Antisense Oligonucleotides and siRNAs Directed Against the Same Targets in Mammalian Cells

21 January 2018

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Effective small interfering RNAs and phosphorothioate antisense DNAs have different preferences for target sites in the luciferase mRNAs

21 January 2018

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The activity of siRNA in mammalian cells is related to structural target accessibility: a comparison with antisense oligonucleotides

21 January 2018

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Comparison of different antisense strategies in mammalian cells using locked nucleic acids, 2'-O-methyl RNA, phosphorothioates and small interfering RNA.

21 January 2018

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Clearance of hepatitis B virus from the liver of transgenic mice by short hairpin RNAs

21 January 2018

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Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing

21 January 2018

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Rational siRNA design for RNA interference

21 January 2018

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An algorithm for selection of functional siRNA sequences.

21 January 2018

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Approaches for the sequence-specific knockdown of mRNA.

21 January 2018

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Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells

21 January 2018

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A system for stable expression of short interfering RNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Inhibition of influenza virus production in virus-infected mice by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Inhibition of respiratory viruses by nasally administered siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Small interfering RNA targeting heme oxygenase-1 enhances ischemia-reperfusion-induced lung apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Reducing hypothalamic AGRP by RNA interference increases metabolic rate and decreases body weight without influencing food intake

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

siRNA relieves chronic neuropathic pain

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Activity of stabilized short interfering RNA in a mouse model of hepatitis B virus replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Cationic liposome-mediated delivery of siRNAs in adult mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Steroid and lipid conjugates of siRNAs to enhance cellular uptake and gene silencing in liver cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

In vivo knockdown of gene expression in brain cancer with intravenous RNAi in adult rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Intravenous RNA interference gene therapy targeting the human epidermal growth factor receptor prolongs survival in intracranial brain cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Intravenous, non-viral RNAi gene therapy of brain cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

In vivo transfer and expression of genes coding for short interfering RNAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

RNA interference: the silent treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Expression profiling reveals off-target gene regulation by RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Cationic lipids enhance siRNA-mediated interferon response in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Specificity of short interfering RNA determined through gene expression signatures

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Genomewide view of gene silencing by small interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Activation of the interferon system by short-interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Interferon induction by siRNAs and ssRNAs synthesized by phage polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

A microRNA in a multiple-turnover RNAi enzyme complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Positional effects of short interfering RNAs targeting the human coagulation trigger Tissue Factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Numerous microRNPs in neuronal cells containing novel microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

RNA interference: the fragile X syndrome connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

The role of small RNAs in human diseases: potential troublemaker and therapeutic tools

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Reduced expression of Dicer associated with poor prognosis in lung cancer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Accumulation of miR-155 and BIC RNA in human B cell lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

RAS is regulated by the let-7 microRNA family

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

MicroRNA expression profiles classify human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

c-Myc-regulated microRNAs modulate E2F1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

A microRNA polycistron as a potential human oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Human immunodeficiency virus type 1 escape from RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Poliovirus escape from RNA interference: short interfering RNA-target recognition and implications for therapeutic approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

RNA interference-mediated control of hepatitis B virus and emergence of resistant mutant.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Hepatitis C Virus Replicons Escape RNA Interference Induced by a Short Interfering RNA Directed against the NS5b Coding Region

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Efficient RNA interference depends on global context of the target sequence: quantitative analysis of silencing efficiency using Eulerian graph representation of siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Local RNA target structure influences siRNA efficacy: systematic analysis of intentionally designed binding regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Inhibition of retroviral pathogenesis by RNA interference.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Susceptibility of human hepatitis delta virus RNAs to small interfering RNA action

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Phenotypic silencing of cytoplasmic genes using sequence-specific double-stranded short interfering RNA and its application in the reverse genetics of wild type negative-strand RNA viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Silencing of H-ras gene expression by retrovirus-mediated siRNA decreases transformation efficiency and tumorgrowth in a model of human ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

RNA interference using boranophosphate siRNAs: structure-activity relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

siRNA function in RNAi: a chemical modification analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

RNA interference in mammalian cells by chemically-modified RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Structural variations and stabilising modifications of synthetic siRNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Inhibition of Virus Replication by RNA Interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

The utility of siRNA transcripts produced by RNA polymerase i in down regulating viral gene expression and replication of negative- and positive-strand RNA viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Use of RNA interference to prevent lethal murine west nile virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Interfering with hepatitis C virus RNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

RNA interference in adult mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Targeting 2A protease by RNA interference attenuates coxsackieviral cytopathogenicity and promotes survival in highly susceptible mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Use of siRNAs to prevent and treat influenza virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Protection against lethal influenza virus challenge by RNA interference in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Selective inhibition of hepatitis B virus replication by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Short interfering RNA-directed inhibition of hepatitis B virus replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Inhibition of hepatitis B virus expression and replication by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Inhibition of hepatitis B virus in mice by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Small interfering RNA Inhibits Hepatitis B virus replication in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Silencing SARS-CoV Spike protein expression in cultured cells by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Small interfering RNA molecules as potential anti-human rhinovirus agents: in vitro potency, specificity, and mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Short interfering RNA confers intracellular antiviral immunity in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Selective silencing of viral gene expression in HPV-positive human cervical carcinoma cells treated with siRNA, a primer of RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Inhibition of human cytomegalovirus replication by small interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

RNA interference as a new strategy against viral hepatitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Exploiting the RNA interference pathway to counter hepatitis B virus replication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Hydrodynamic injection of viral DNA: a mouse model of acute hepatitis B virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Inhibition of hepatitis B virus replication in vivo by nucleoside analogues and siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Sustained small interfering RNA-mediated human immunodeficiency virus type 1 inhibition in primary macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

RNA interference: from model organisms towards therapy for neural and neuromuscular disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Therapeutic gene silencing in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

In vitro and in vivo suppression of GJB2 expression by RNA interference.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Effects of treatment with small interfering RNA on joint inflammation in mice with collagen-induced arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Caspase 8 small interfering RNA prevents acute liver failure in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Caspase-8 and caspase-3 small interfering RNA decreases ischemia/reperfusion injury to the liver in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Small interfering RNA targeting Fas protects mice against renal ischemia-reperfusion injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

An RNAi strategy for treatment of amyotrophic lateral sclerosis caused by mutant Cu,Zn superoxide dismutase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

SCA1 transgenic mice: A model for neurodegeneration caused by an expanded CAG trinucleotide repeat

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Recovery from polyglutamine-induced neurodegeneration in conditional SCA1 transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

BACE1 Suppression by RNA Interference in Primary Cortical Neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Silencing of disease-related genes by small interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Antitumor activity of small interfering RNA/cationic liposome complex in mouse models of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

RNA interference targeting focal adhesion kinase enhances pancreatic adenocarcinoma gemcitabine chemosensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

EphA2: a determinant of malignant cellular behavior and a potential therapeutic target in pancreatic adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Cancer inhibition in nude mice after systemic application of U6 promoter-driven short hairpin RNAs against PLK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Colony-stimulating factor-1 blockade by antisense oligonucleotides and small interfering RNAs suppresses growth of human mammary tumor xenografts in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Survivin-directed RNA interference cocktail is a potent suppressor of tumour growth in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Gene therapy for human small-cell lung carcinoma by inactivation of Skp-2 with virally mediated RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Anti-RhoA and anti-RhoC siRNAs inhibit the proliferation and invasiveness of MDA-MB-231 breast cancer cells in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

A small interfering RNA targeting vascular endothelial growth factor as cancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

RNA interference is a functional pathway with therapeutic potential in human myeloid leukemia cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Synthetic small inhibiting RNAs: efficient tools to inactivate oncogenic mutations and restore p53 pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Antisense to apoptosis inhibitors facilitates chemotherapy and TRAIL-induced death signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Molecular targeting therapy of cancer: drug resistance, apoptosis and survival signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Modulation of the classical multidrug resistance (MDR) phenotype by RNA interference (RNAi).

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Complete reversal of multidrug resistance by stable expression of small interfering RNAs targeting MDR1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

CXCR4 knockdown by small interfering RNA abrogates breast tumor growth in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

Modulation of angiogenesis with siRNA inhibitors for novel therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

The benefit/risk profile of TNF-blocking agents: findings of a consensus panel

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2005.08.004

A randomized controlled clinical trial of intravitreous fomivirsen for treatment of newly diagnosed peripheral cytomegalovirus retinitis in patients with AIDS.

21 January 2018

1 reference

12 December 2020

Suppression of chemokine receptor expression by RNA interference allows for inhibition of HIV-1 replication

1 reference

12 December 2020

Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model.

1 reference

12 December 2020

RNA interference targeting transforming growth factor-beta type II receptor suppresses ocular inflammation and fibrosis.

1 reference

12 December 2020

High-level hepatitis B virus replication in transgenic mice

1 reference

12 December 2020

Small interfering RNA-mediated gene silencing in T lymphocytes

1 reference

12 December 2020

SiRNA-mediated inhibition of vascular endothelial growth factor severely limits tumor resistance to antiangiogenic thrombospondin-1 and slows tumor vascularization and growth.

1 reference

12 December 2020

Down-regulation of CXCR4 by inducible small interfering RNA inhibits breast cancer cell invasion in vitro

1 reference

12 December 2020

Lack of interferon response in animals to naked siRNAs

1 reference

12 December 2020

Systemic siRNA-mediated gene silencing: a new approach to targeted therapy of cancer.

1 reference

12 December 2020

Sensing the danger in RNA

1 reference

12 December 2020

RNA interference targeting Fas protects mice from fulminant hepatitis

1 reference

12 December 2020

Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: therapeutic strategy for herpetic stromal keratitis

1 reference

12 December 2020

siRNA-directed inhibition of HIV-1 infection

1 reference

12 December 2020

RNA interference as an antiviral approach: targeting HIV-1.

1 reference

12 December 2020

Antisense inhibition: oligonucleotides, ribozymes, and siRNAs.

1 reference

12 December 2020

Induction of apoptosis in HeLa cells with siRNA expression vector targeted against bcl-2

1 reference

12 December 2020

Targeting angiogenesis, the underlying disorder in neovascular age-related macular degeneration

1 reference

12 December 2020

1 reference

12 December 2020

Toward therapy for DYT1 dystonia: allele-specific silencing of mutant TorsinA

1 reference

12 December 2020

Inhibition of viral growth by antisense oligonucleotides directed against the IE110 and the UL30 mRNA of herpes simplex virus type-1.

1 reference

12 December 2020

Why do we need new gene therapy viral vectors? Characteristics, limitations and future perspectives of viral vector transduction

1 reference

12 December 2020

Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors

1 reference

12 December 2020

Requirement for sphingosine 1-phosphate receptor-1 in tumor angiogenesis demonstrated by in vivo RNA interference

1 reference

12 December 2020

Silence is golden: can RNA interference therapeutics deliver?

1 reference

12 December 2020

Choosing CCR5 or Rev siRNA in HIV-1

1 reference

12 December 2020

1 reference

12 December 2020

Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3.

1 reference

12 December 2020

Silencing of CXCR4 blocks breast cancer metastasis

1 reference

12 December 2020

Gene silencing by systemic delivery of synthetic siRNAs in adult mice

1 reference

12 December 2020

Small interfering RNAs directed against beta-catenin inhibit the in vitro and in vivo growth of colon cancer cells

1 reference

12 December 2020

Silencing expression of the catalytic subunit of DNA-dependent protein kinase by small interfering RNA sensitizes human cells for radiation-induced chromosome damage, cell killing, and mutation.

1 reference

12 December 2020

Enhanced radiation and chemotherapy-mediated cell killing of human cancer cells by small inhibitory RNA silencing of DNA repair factors.

1 reference

12 December 2020

10.1016/J.FEBSLET.2005.08.004

Identifiers

DOI

1 reference

13 August 2017

1 reference