(Q36247123)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

title

Wnt-pathway activation in two molecular classes of hepatocellular carcinoma and experimental modulation by sorafenib (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

main subject

hepatocellular carcinoma

1 reference

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Beatriz Mínguez

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Jordi Barretina Ginesta

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Jordi Bruix

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Vincenzo Mazzaferro

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Josep M. Llovet

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

16

Myron Schwartz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

6

Yujin Hoshida

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

2

Clara Alsinet

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

12

Swan Thung

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

9

Philippa Newell

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

5

Sara Toffanin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

4

Laia Cabellos

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1

Anja Lachenmayer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

3

Radoslav Savic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

author name string

Hung-Wen Tsai

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Stephen C Ward

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Scott L Friedman

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

language of work or name

English

0 references

publication date

18 July 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

published in

Clinical Cancer Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

volume

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

issue

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

page(s)

4997-5007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

Essential requirement for β-arrestin2 in mouse intestinal tumors with elevated Wnt signaling

8 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

Wnt-β-catenin-Tcf-4 signalling-modulated invasiveness is dependent on osteopontin expression in breast cancer

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

MicroRNA-based classification of hepatocellular carcinoma and oncogenic role of miR-517a

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

1 October 2017

Global cancer statistics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

Beta-catenin signaling, liver regeneration and hepatocellular cancer: sorting the good from the bad.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

Nearest template prediction: a single-sample-based flexible class prediction with confidence assessment

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

Inactivation of PI3K/AKT signaling inhibits glioma cell growth through modulation of β-catenin-mediated transcription

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

Sorafenib: a clinical and pharmacologic review

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

Sorafenib downregulates ERK/Akt and STAT3 survival pathways and induces apoptosis in a human neuroblastoma cell line

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

Molecular classification and novel targets in hepatocellular carcinoma: recent advancements

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

Canonical Wnt signaling is antagonized by noncanonical Wnt5a in hepatocellular carcinoma cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

Pivotal role of mTOR signaling in hepatocellular carcinoma

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

Focal gains of VEGFA and molecular classification of hepatocellular carcinoma

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

Sorafenib in advanced hepatocellular carcinoma

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

Common dysregulation of Wnt/Frizzled receptor elements in human hepatocellular carcinoma

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

Wnt signalling and its impact on development and cancer

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

EpCAM and alpha-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

Activation of hepatic stem cell marker EpCAM by Wnt-beta-catenin signaling in hepatocellular carcinoma

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

Analysis of endogenous LRP6 function reveals a novel feedback mechanism by which Wnt negatively regulates its receptor

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

Wnt signalling: variety at the core.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

Aberrant expression and function of TCF4 in the proliferation of hepatocellular carcinoma cell line BEL-7402.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

FRAT1 and FRAT2, clustered in human chromosome 10q24.1 region, are up-regulated in gastric cancer

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

Molecular cloning and characterization of FRAT2, encoding a positive regulator of the WNT signaling pathway

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

KEGG: kyoto encyclopedia of genes and genomes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

More powerful procedures for multiple significance testing

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

Distinct p53 gene signatures are needed to predict prognosis and response to chemotherapy in ER-positive and ER-negative breast cancers

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

Liver zonation occurs through a beta-catenin-dependent, c-Myc-independent mechanism.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

Functional consequences of frizzled-7 receptor overexpression in human hepatocellular carcinoma.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446854

P53 mutation as a source of aberrant beta-catenin accumulation in cancer cells

22 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22811581

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Differential effects of inactivated Axin1 and activated beta-catenin mutations in human hepatocellular carcinomas

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22811581

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Hepatocellular adenoma subtype classification using molecular markers and immunohistochemistry

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22811581

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/1078-0432.CCR-11-2322

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22811581%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

PubMed publication ID

22811581

1 reference