(Q36249157)

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Intracellular protein degradation: from a vague idea, through the lysosome and the ubiquitin-proteasome system, and onto human diseases and drug targeting (Nobel lecture).

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scholarly article

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Europe PubMed Central

PubMed publication ID

13 August 2017

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Europe PubMed Central

Intracellular protein degradation: from a vague idea, through the lysosome and the ubiquitin-proteasome system, and onto human diseases and drug targeting (Nobel lecture). (English)

1 reference

Europe PubMed Central

PubMed publication ID

13 August 2017

ubiquitin-proteasome system

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Aaron Ciechanover

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object named as

Aaron Ciechanover

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Europe PubMed Central

PubMed publication ID

13 August 2017

language of work or name

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publication date

1 September 2005

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Europe PubMed Central

PubMed publication ID

13 August 2017

Angewandte Chemie International Edition

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44

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Europe PubMed Central

PubMed publication ID

13 August 2017

37

1 reference

Europe PubMed Central

PubMed publication ID

13 August 2017

5944-5967

1 reference

Europe PubMed Central

PubMed publication ID

13 August 2017

Molecular mechanisms of bitter and sweet taste transduction

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Tissue fractionation studies. 4. Comparative study of the binding of acid phosphatase, β-glucuronidase and cathepsin by rat-liver particles

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Selective control of the degradation of normal and aberrant proteins in Reuber H35 hepatoma cells

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Turnover of protein in growing and non-growing populations of Escherichia coli

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H2B ubiquitylation: the end is in sight

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The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

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Occurrence of a polyubiquitin structure in ubiquitin-protein conjugates

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Transcriptional regulation by histone ubiquitination and deubiquitination.

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Hitler's gift and the era of biosynthesis

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Thermolability of ubiquitin-activating enzyme from the mammalian cell cycle mutant ts85

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Proposed role of ATP in protein breakdown: conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis

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ATP-dependent degradation of ubiquitin-protein conjugates

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Ubiquitin dependence of selective protein degradation demonstrated in the mammalian cell cycle mutant ts85

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Proteolysis: from the lysosome to ubiquitin and the proteasome

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Functions of lysosomes

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A soluble ATP-dependent proteolytic system responsible for the degradation of abnormal proteins in reticulocytes

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ATP serves two distinct roles in protein degradation in reticulocytes, one requiring and one independent of ubiquitin

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Attempts to Map a Process Evolution of Peptide Biosynthesis

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Isopeptide linkage between nonhistone and histone 2A polypeptides of chromosomal conjugate-protein A24

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ATP-dependent incorporation of 20S protease into the 26S complex that degrades proteins conjugated to ubiquitin

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Identifiers

10.1002/ANIE.200501428

1 reference

Europe PubMed Central

PubMed publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 August 2017

ResearchGate publication ID

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