(Q36252497)

13 August 2017

Chromosome 4q25 variants are genetic modifiers of rare ion channel mutations associated with familial atrial fibrillation (English)

1 reference

familial atrial fibrillation

13 August 2017

0 references

1 reference

1

Marylyn D Ritchie

1 reference

13 August 2017

7

Dan M Roden

1 reference

13 August 2017

8

Dawood Darbar

1 reference

13 August 2017

6

Shannon Carter

1 reference

13 August 2017

3

Gayle Kucera

1 reference

13 August 2017

4

Tanya Stubblefield

1 reference

13 August 2017

5

Marcia Blair

1 reference

13 August 2017

Shane Rowan

2

1 reference

PMC publication ID

3448817

13 August 2017

language of work or name

English

0 references

publication date

18 July 2012

1 reference

Journal of the American College of Cardiology

13 August 2017

1 reference

13 August 2017

60

1 reference

13 August 2017

13

1 reference

13 August 2017

1173-1181

1 reference

HRS/EHRA expert consensus statement on the state of genetic testing for the channelopathies and cardiomyopathies this document was developed as a partnership between the Heart Rhythm Society (HRS) and the European Heart Rhythm Association (EHRA).

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Novel KCNA5 mutation implicates tyrosine kinase signaling in human atrial fibrillation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Pitx2 prevents susceptibility to atrial arrhythmias by inhibiting left-sided pacemaker specification

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Common variants in KCNN3 are associated with lone atrial fibrillation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Variation in the 4q25 chromosomal locus predicts atrial fibrillation after coronary artery bypass graft surgery

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Augmented potassium current is a shared phenotype for two genetic defects associated with familial atrial fibrillation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Prevention of atrial fibrillation: report from a national heart, lung, and blood institute workshop

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Large scale replication and meta-analysis of variants on chromosome 4q25 associated with atrial fibrillation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

A first-degree family history in lone atrial fibrillation patients

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Cardiac sodium channel (SCN5A) variants associated with atrial fibrillation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Prolonged signal-averaged P-wave duration as an intermediate phenotype for familial atrial fibrillation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Genetics of atrial fibrillation: rare mutations, common polymorphisms, and clinical relevance

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Myocardial Pitx2 differentially regulates the left atrial identity and ventricular asymmetric remodeling programs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Pitx2c and Nkx2-5 are required for the formation and identity of the pulmonary myocardium

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Variants conferring risk of atrial fibrillation on chromosome 4q25.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Polymorphism modulates symptomatic response to antiarrhythmic drug therapy in patients with lone atrial fibrillation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Potassium channel gene mutations rarely cause atrial fibrillation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Secular trends in incidence of atrial fibrillation in Olmsted County, Minnesota, 1980 to 2000, and implications on the projections for future prevalence

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Kv1.5 channelopathy due to KCNA5 loss-of-function mutation causes human atrial fibrillation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Lifetime risk for development of atrial fibrillation: the Framingham Heart Study

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Parental atrial fibrillation as a risk factor for atrial fibrillation in offspring

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Familial atrial fibrillation is a genetically heterogeneous disorder.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

KCNQ1 gain-of-function mutation in familial atrial fibrillation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Familial aggregation of atrial fibrillation in Iceland

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Mutations in the long QT gene, KCNQ1, are an uncommon cause of atrial fibrillation

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Chromosome 4q25 variants and atrial fibrillation recurrence after catheter ablation.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

PITX2c Is Expressed in the Adult Left Atrium, and Reducing Pitx2c Expression Promotes Atrial Fibrillation Inducibility and Complex Changes in Gene Expression

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Common Variants in Myocardial Ion Channel Genes Modify the QT Interval in the General Population

5 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3448817

Echocardiographic criteria for left ventricular hypertrophy: the Framingham Heart Study

5 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22818067

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Familial aggregation in lone atrial fibrillation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22818067

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.JACC.2012.04.030

1 reference

13 August 2017

1 reference

PMC publication ID

3448817

13 August 2017

PubMed publication ID

22818067

1 reference

PMC publication ID

3448817