Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q36254079)
Watch
English
Fbxw7 Limits Myelination by Inhibiting mTOR Signaling.
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
4635133
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26538655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
title
Fbxw7 Limits Myelination by Inhibiting mTOR Signaling
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
4635133
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26538655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
main subject
myelination
1 reference
based on heuristic
inferred from title
author
Andrew M. Ravanelli
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4635133
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26538655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
author name string
Christina A Kearns
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4635133
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26538655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
Kirsten Cooper
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
4635133
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26538655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
Bruce Appel
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
4635133
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26538655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
language of work or name
English
0 references
publication date
1 November 2015
1 reference
stated in
Europe PubMed Central
PMC publication ID
4635133
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26538655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
published in
Journal of Neuroscience
1 reference
stated in
Europe PubMed Central
PMC publication ID
4635133
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26538655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
volume
35
1 reference
stated in
Europe PubMed Central
PMC publication ID
4635133
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26538655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
issue
44
1 reference
stated in
Europe PubMed Central
PMC publication ID
4635133
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26538655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
page(s)
14861-14871
1 reference
stated in
Europe PubMed Central
PMC publication ID
4635133
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26538655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
cites work
A Basal Tone of 2-Arachidonoylglycerol Contributes to Early Oligodendrocyte Progenitor Proliferation by Activating Phosphatidylinositol 3-Kinase (PI3K)/AKT and the Mammalian Target of Rapamycin (MTOR) Pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
Conditional ablation of raptor or rictor has differential impact on oligodendrocyte differentiation and CNS myelination.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
Mammalian target of rapamycin promotes oligodendrocyte differentiation, initiation and extent of CNS myelination.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
Mechanisms regulating the development of oligodendrocytes and central nervous system myelin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
mTOR: a link from the extracellular milieu to transcriptional regulation of oligodendrocyte development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
A critical period for social experience-dependent oligodendrocyte maturation and myelination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
Fbxw7 regulates Notch to control specification of neural precursors for oligodendrocyte fate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
mTOR signaling in growth control and disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
Erk1/2 MAPK and mTOR signaling sequentially regulates progression through distinct stages of oligodendrocyte differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
Proteomic identification of novel targets regulated by the mammalian target of rapamycin pathway during oligodendrocyte differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
Haploinsufficiency of target of rapamycin attenuates cardiomyopathies in adult zebrafish
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
A selective glial barrier at motor axon exit points prevents oligodendrocyte migration from the spinal cord
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
Akt signals through the mammalian target of rapamycin pathway to regulate CNS myelination.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
Activation of the mammalian target of rapamycin (mTOR) is essential for oligodendrocyte differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
Neuregulin-1/ErbB signaling serves distinct functions in myelination of the peripheral and central nervous system.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
Constitutively active Akt induces enhanced myelination in the CNS
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
The Tol2kit: a multisite gateway-based construction kit for Tol2 transposon transgenesis constructs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
Multiple sclerosis: re-expression of a developmental pathway that restricts oligodendrocyte maturation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
Notch1 control of oligodendrocyte differentiation in the spinal cord
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
Functional interaction between SEL-10, an F-box protein, and the nuclear form of activated Notch1 receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
Stages of embryonic development of the zebrafish
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
30 September 2017
Elevated phosphatidylinositol 3,4,5-trisphosphate in glia triggers cell-autonomous membrane wrapping and myelination.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
29 June 2018
In vivo actions of fibroblast growth factor-2 and insulin-like growth factor-I on oligodendrocyte development and myelination in the central nervous system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
29 June 2018
Notch receptor activation inhibits oligodendrocyte differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
29 June 2018
Oligodendrocyte population dynamics and the role of PDGF in vivo.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
29 June 2018
Composition of myelin from peripheral and central nervous systems of the squirrel monkey
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
29 June 2018
Balanced mTORC1 activity in oligodendrocytes is required for accurate CNS myelination.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
22 September 2018
Schwann cell myelination requires Dynein function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
22 September 2018
Identification of genes expressed by zebrafish oligodendrocytes using a differential microarray screen.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
22 September 2018
A direct role for Sox10 in specification of neural crest-derived sensory neurons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
22 September 2018
Oligodendrocyte specification in zebrafish requires notch-regulated cyclin-dependent kinase inhibitor function.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
22 September 2018
Neural cell fate analysis in zebrafish using olig2 BAC transgenics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
22 September 2018
Delta-Notch signaling regulates oligodendrocyte specification
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
22 September 2018
Myelination is altered in insulin-like growth factor-I null mutant mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
22 September 2018
Characterization of myelination in the developing zebrafish
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
22 September 2018
Central nervous system myelination in mice with deficient expression of Notch1 receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
22 September 2018
Multicolor whole-mount in situ hybridization.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
22 September 2018
Defective oligodendrocyte development and severe hypomyelination in PDGF-A knockout mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
22 September 2018
Insulin-like growth factor I increases brain growth and central nervous system myelination in transgenic mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4635133
retrieved
22 September 2018
GSK3β negatively regulates oligodendrocyte differentiation and myelination in vivo
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26538655
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1523/JNEUROSCI.4968-14.2015
1 reference
stated in
Europe PubMed Central
PMC publication ID
4635133
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26538655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
PMC publication ID
4635133
1 reference
stated in
Europe PubMed Central
PMC publication ID
4635133
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26538655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
PubMed publication ID
26538655
1 reference
stated in
Europe PubMed Central
PMC publication ID
4635133
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26538655%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 February 2020
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
