Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q36275152)
Watch
English
LC-MS-based metabolomics in drug metabolism
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
2140249
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17786640%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
review article
1 reference
stated in
Europe PubMed Central
title
LC-MS-based metabolomics in drug metabolism
(English)
1 reference
stated in
Europe PubMed Central
PMCID
2140249
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17786640%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
main subject
metabolomics
1 reference
based on heuristic
inferred from title
author
Chi Chen
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
2140249
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17786640%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
Jeff Idle
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
2140249
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17786640%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
author name string
Frank J Gonzalez
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
2140249
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17786640%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
language of work or name
English
0 references
publication date
1 January 2007
1 reference
stated in
Europe PubMed Central
PMCID
2140249
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17786640%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
published in
Drug Metabolism Reviews
1 reference
stated in
Europe PubMed Central
PMCID
2140249
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17786640%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
volume
39
1 reference
stated in
Europe PubMed Central
PMCID
2140249
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17786640%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
page(s)
581-597
1 reference
stated in
Europe PubMed Central
PMCID
2140249
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17786640%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
issue
2-3
1 reference
stated in
Europe PubMed Central
PMCID
2140249
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17786640%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
cites work
The fate of acetanilide in man.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Data processing for mass spectrometry-based metabolomics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Application of chimeric mice with humanized liver for predictive ADME.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Normalization method for metabolomics data using optimal selection of multiple internal standards
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
A comprehensive investigation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) metabolism in the mouse using a multivariate data analysis approach
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Chemometrics in metabonomics.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
From exogenous to endogenous: the inevitable imprint of mass spectrometry in metabolomics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
HMDB: the Human Metabolome Database
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Metabolic profiling technologies for biomarker discovery in biomedicine and drug development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Can personalized drug therapy be achieved? A closer look at pharmaco-metabonomics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Comparing and combining NMR spectroscopy and mass spectrometry in metabolomics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Plant metabolomics: towards biological function and mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Computational prediction of human drug metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Mass spectrometry-based metabolomics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Detection and characterization of metabolites in biological matrices using mass defect filtering of liquid chromatography/high resolution mass spectrometry data
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
3,4-Dehydrodebrisoquine, a novel debrisoquine metabolite formed from 4-hydroxydebrisoquine that affects the CYP2D6 metabolic ratio
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
A metabolomic approach to the metabolism of the areca nut alkaloids arecoline and arecaidine in the mouse
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Urinary metabolite profiling reveals CYP1A2-mediated metabolism of NSC686288 (aminoflavone).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Pharmaco-metabonomic phenotyping and personalized drug treatment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
The Cinderella story of metabolic profiling: does metabolomics get to go to the functional genomics ball?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Thiopurine S-methyltransferase pharmacogenetics: insights, challenges and future directions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Cytochrome P450 and xenobiotic receptor humanized mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Accelerated throughput metabolic route screening in early drug discovery using high-resolution liquid chromatography/quadrupole time-of-flight mass spectrometry and automated data analysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Microbial metabolomics: replacing trial-and-error by the unbiased selection and ranking of targets.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Cytochrome P450 humanised mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Stable isotope labeling of Arabidopsis thaliana for an NMR-based metabolomics approach
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Near completely humanized liver in mice shows human-type metabolic responses to drugs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Role of gene knockout and transgenic mice in the study of xenobiotic metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Drug Metabolism and Drug Interactions: Application and Clinical Value of In Vitro Models
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Inactivation of the hepatic cytochrome P450 system by conditional deletion of hepatic cytochrome P450 reductase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Metabonomics: a platform for studying drug toxicity and gene function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: a pharmacogenetic analysis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Pharmacogenomics: translating functional genomics into rational therapeutics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Characterization of the common genetic defect in humans deficient in debrisoquine metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Metabolism of debrisoquine sulphate in rat, dog and man
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
The metabolism of [14C]-debrisoquine in man
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Metabolism of debrisoquine sulfate. Identification of some urinary metabolites in rat and man
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Polymorphic hydroxylation of Debrisoquine in man.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
30 September 2017
Drug metabolite identification: stable isotope methods
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
29 June 2018
When good drugs go bad.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
22 September 2018
High-performance liquid chromatography separations coupled with coulometric electrode array detectors: a unique approach to metabolomics.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
22 September 2018
High resolution "ultra performance" liquid chromatography coupled to oa-TOF mass spectrometry as a tool for differential metabolic pathway profiling in functional genomic studies.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
22 September 2018
Understanding 'Global' Systems Biology: Metabonomics and the Continuum of Metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
22 September 2018
Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics
2 references
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
22 September 2018
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1080%2F03602530701497804
retrieved
21 January 2018
Achievement of a 920-MHz high resolution NMR.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2140249
retrieved
22 September 2018
Metabolite profiling: from diagnostics to systems biology
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17786640
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
1- and 3-hydroxylations, in addition to 4-hydroxylation, of debrisoquine are catalyzed by cytochrome P450 2D6 in humans
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17786640
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The metabolomics of (+/-)-arecoline 1-oxide in the mouse and its formation by human flavin-containing monooxygenases
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17786640
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Hypotensive response to debrisoquine and hydroxylation phenotype
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17786640
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Use of liquid chromatography/time-of-flight mass spectrometry and multivariate statistical analysis shows promise for the detection of drug metabolites in biological fluids
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17786640
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Oxidation of the antihistaminic drug terfenadine in human liver microsomes. Role of cytochrome P-450 3A(4) in N-dealkylation and C-hydroxylation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17786640
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1080/03602530701497804
1 reference
stated in
Europe PubMed Central
PMCID
2140249
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17786640%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
PMCID
2140249
1 reference
stated in
Europe PubMed Central
PMCID
2140249
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17786640%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
PubMed ID
17786640
1 reference
stated in
Europe PubMed Central
PMCID
2140249
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17786640%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
ResearchGate publication ID
6053188
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
