(Q36276274)

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HIV-1 neutralizing antibodies display dual recognition of the primary and coreceptor binding sites and preferential binding to fully cleaved envelope glycoproteins

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Europe PubMed Central

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13 August 2017

HIV-1 neutralizing antibodies display dual recognition of the primary and coreceptor binding sites and preferential binding to fully cleaved envelope glycoproteins (English)

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Europe PubMed Central

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13 August 2017

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John R. Mascola

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John R Mascola

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13 August 2017

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Mario Roederer

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13 August 2017

Nicole Doria-Rose

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Nicole Doria-Rose

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13 August 2017

Bimal K. Chakrabarti

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Bimal K Chakrabarti

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13 August 2017

Richard T. Wyatt

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Richard T Wyatt

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13 August 2017

Stephen D Schmidt

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Stephen D Schmidt

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13 August 2017

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Mark K Louder

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13 August 2017

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Nancy S Longo

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13 August 2017

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Sijy O'Dell

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Carl-Magnus Hogerkorp

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Carl-Magnus Hogerkorp

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Javier Guenaga

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13 August 2017

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Yuxing Li

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13 August 2017

Richard Wilson

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13 August 2017

Xueling Wu

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Christian Poulsen

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Mark Connors

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publication date

8 August 2012

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13 August 2017

Journal of Virology

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13 August 2017

86

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13 August 2017

20

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Europe PubMed Central

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13 August 2017

11231-11241

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Europe PubMed Central

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13 August 2017

Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops

1 reference

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30 September 2017

Selection pressure on HIV-1 envelope by broadly neutralizing antibodies to the conserved CD4-binding site

1 reference

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30 September 2017

Identification and characterization of an immunogenic hybrid epitope formed by both HIV gp120 and human CD4 proteins

1 reference

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30 September 2017

Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

1 reference

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30 September 2017

High-resolution description of antibody heavy-chain repertoires in humans

1 reference

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30 September 2017

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

1 reference

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30 September 2017

Mechanism of neutralization by the broadly neutralizing HIV-1 monoclonal antibody VRC01.

1 reference

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30 September 2017

HIV type 1 Env precursor cleavage state affects recognition by both neutralizing and nonneutralizing gp41 antibodies

1 reference

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30 September 2017

Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1

1 reference

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30 September 2017

The role of antibodies in HIV vaccines

1 reference

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30 September 2017

Analysis of memory B cell responses and isolation of novel monoclonal antibodies with neutralizing breadth from HIV-1-infected individuals

1 reference

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30 September 2017

A V3 loop-dependent gp120 element disrupted by CD4 binding stabilizes the human immunodeficiency virus envelope glycoprotein trimer.

1 reference

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30 September 2017

Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of neutralizing antibodies

1 reference

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30 September 2017

Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire

1 reference

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30 September 2017

Mechanism of human immunodeficiency virus type 1 resistance to monoclonal antibody B12 that effectively targets the site of CD4 attachment

1 reference

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30 September 2017

Antibody specificities associated with neutralization breadth in plasma from human immunodeficiency virus type 1 subtype C-infected blood donors

1 reference

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30 September 2017

Structure-based stabilization of HIV-1 gp120 enhances humoral immune responses to the induced co-receptor binding site

1 reference

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30 September 2017

Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457177

30 September 2017

Analysis of neutralization specificities in polyclonal sera derived from human immunodeficiency virus type 1-infected individuals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457177

30 September 2017

Factors associated with the development of cross-reactive neutralizing antibodies during human immunodeficiency virus type 1 infection

1 reference

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30 September 2017

Enhancing exposure of HIV-1 neutralization epitopes through mutations in gp41.

1 reference

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30 September 2017

Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457177

30 September 2017

Structures of the CCR5 N Terminus and of a Tyrosine-Sulfated Antibody with HIV-1 gp120 and CD4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457177

30 September 2017

Broad HIV-1 neutralization mediated by CD4-binding site antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457177

30 September 2017

GP120: target for neutralizing HIV-1 antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457177

30 September 2017

Characterization of antibody responses elicited by human immunodeficiency virus type 1 primary isolate trimeric and monomeric envelope glycoproteins in selected adjuvants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457177

30 September 2017

Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457177

30 September 2017

Antigenic conservation and immunogenicity of the HIV coreceptor binding site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457177

30 September 2017

Selective recognition of oligomeric HIV-1 primary isolate envelope glycoproteins by potently neutralizing ligands requires efficient precursor cleavage.

1 reference

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30 September 2017

Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120

1 reference

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30 September 2017

Epitope mapping and characterization of a novel CD4-induced human monoclonal antibody capable of neutralizing primary HIV-1 strains

1 reference

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30 September 2017

Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1

1 reference

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Predominant autoantibody production by early human B cell precursors

1 reference

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30 September 2017

Characterization of CD4-induced epitopes on the HIV type 1 gp120 envelope glycoprotein recognized by neutralizing human monoclonal antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457177

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The crown and stem of the V3 loop play distinct roles in human immunodeficiency virus type 1 envelope glycoprotein interactions with the CCR5 coreceptor

1 reference

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Mapping the determinants of the CCR5 amino-terminal sulfopeptide interaction with soluble human immunodeficiency virus type 1 gp120-CD4 complexes

1 reference

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30 September 2017

Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457177

30 September 2017

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457177

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A conserved HIV gp120 glycoprotein structure involved in chemokine receptor binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457177

30 September 2017

The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457177

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CD4-Induced conformational changes in the human immunodeficiency virus type 1 gp120 glycoprotein: consequences for virus entry and neutralization

1 reference

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CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5.

1 reference

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Antibody cross-competition analysis of the human immunodeficiency virus type 1 gp120 exterior envelope glycoprotein.

1 reference

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Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody

1 reference

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Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding

1 reference

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30 September 2017

Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1.

1 reference

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30 September 2017

Biosynthesis, cleavage, and degradation of the human immunodeficiency virus 1 envelope glycoprotein gp160.

1 reference

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30 September 2017

Intracellular processing of the gp160 HIV-1 envelope precursor. Endoproteolytic cleavage occurs in a cis or medial compartment of the Golgi complex

1 reference

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Characterization of the multiple conformational States of free monomeric and trimeric human immunodeficiency virus envelope glycoproteins after fixation by cross-linker

1 reference

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29 June 2018

Characterization of the human Ig heavy chain antigen binding complementarity determining region 3 using a newly developed software algorithm, JOINSOLVER.

1 reference

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22 September 2018

Structure-based, targeted deglycosylation of HIV-1 gp120 and effects on neutralization sensitivity and antibody recognition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457177

22 September 2018

Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entry

1 reference

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Fine definition of a conserved CCR5-binding region on the human immunodeficiency virus type 1 glycoprotein 120

1 reference

https://pubmed.ncbi.nlm.nih.gov/22875963

12 December 2020

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Identifiers

10.1128/JVI.01543-12

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

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