(Q36285611)

13 August 2017

EGFR-T790M is a rare lung cancer susceptibility allele with enhanced kinase activity (English)

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13 August 2017

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Joan E Bailey-Wilson

9

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Daniela Seminara

23

object named as

Daniela Seminara

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13 August 2017

10

Christopher I Amos

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13 August 2017

16

Pamela R Fain

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13 August 2017

12

Gloria M Petersen

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13 August 2017

13

Mariza de Andrade

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13 August 2017

17

Ann G Schwartz

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13 August 2017

Haris Vikis

1

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13 August 2017

Mitsuo Sato

2

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13 August 2017

Michael James

3

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13 August 2017

Daolong Wang

4

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13 August 2017

Yian Wang

5

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13 August 2017

Min Wang

6

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13 August 2017

Dongmei Jia

7

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13 August 2017

Yan Liu

8

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13 August 2017

Susan M Pinney

11

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13 August 2017

Ping Yang

14

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13 August 2017

Jonathan S Wiest

15

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13 August 2017

Adi Gazdar

18

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13 August 2017

Colette Gaba

19

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13 August 2017

Henry Rothschild

20

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13 August 2017

Diptasri Mandal

21

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13 August 2017

Elena Kupert

22

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13 August 2017

Avinash Viswanathan

24

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13 August 2017

Ramaswamy Govindan

25

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13 August 2017

John Minna

26

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13 August 2017

Marshall W Anderson

27

1 reference

13 August 2017

Ming You

28

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13 August 2017

language of work or name

English

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publication date

1 May 2007

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13 August 2017

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13 August 2017

67

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13 August 2017

10

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13 August 2017

4665-4670

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Transcriptional profiling identifies cyclin D1 as a critical downstream effector of mutant epidermal growth factor receptor signaling

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460269

Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460269

Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460269

EGFR mutation and resistance of non-small-cell lung cancer to gefitinib

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460269

The development of imatinib as a therapeutic agent for chronic myeloid leukemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460269

EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460269

A major lung cancer susceptibility locus maps to chromosome 6q23-25.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460269

The two major imatinib resistance mutations E255K and T315I enhance the activity of BCR/ABL fusion kinase.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460269

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460269

Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460269

Mutation of threonine 766 in the epidermal growth factor receptor reveals a hotspot for resistance formation against selective tyrosine kinase inhibitors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460269

New therapeutic strategies for lung cancer: biology and molecular biology come of age.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460269

Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460269

Controlling epidermal growth factor (EGF)-stimulated Ras activation in intact cells by a cell-permeable peptide mimicking phosphorylated EGF receptor

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460269

Presence of epidermal growth factor receptor gene T790M mutation as a minor clone in non-small cell lung cancer.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460269

Multiple oncogenic changes (K-RAS(V12), p53 knockdown, mutant EGFRs, p16 bypass, telomerase) are not sufficient to confer a full malignant phenotype on human bronchial epithelial cells.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460269

Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460269

Characterization of a conserved structural determinant controlling protein kinase sensitivity to selective inhibitors.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460269

Segregation analysis of smoking-associated malignancies: evidence for Mendelian inheritance

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460269

Evidence for mendelian inheritance in the pathogenesis of lung cancer

22 September 2018

1 reference

12 December 2020

Expression of mutated epidermal growth factor receptor by non-small cell lung carcinomas

1 reference

12 December 2020

Frequent expression of a mutant epidermal growth factor receptor in multiple human tumors

1 reference

12 December 2020

Lung cancer risk in families of nonsmoking probands: heterogeneity by age at diagnosis

1 reference

12 December 2020

10.1158/0008-5472.CAN-07-0217

Identifiers

DOI

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

17510392

1 reference