(Q36286049)

13 August 2017

Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis (English)

1 reference

13 August 2017

0 references

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2

Mete Civelek

0 references

Stephen D Lee

object named as

Stephen D Lee

6

0 references

Gregory A Fishbein

object named as

Gregory A Fishbein

10

0 references

Aldons Jake Lusis

14

object named as

Aldons J Lusis

1 reference

13 August 2017

15

Peter Tontonoz

1 reference

13 August 2017

Anaïs Briot

1

0 references

author name string

Atsuko Seki

3

1 reference

13 August 2017

Karen Hoi

4

1 reference

13 August 2017

Julia J Mack

5

1 reference

13 August 2017

Jason Kim

7

1 reference

13 August 2017

Cynthia Hong

8

1 reference

13 August 2017

Jingjing Yu

9

1 reference

13 August 2017

Ladan Vakili

11

1 reference

13 August 2017

Alan M Fogelman

12

1 reference

13 August 2017

Michael C Fishbein

13

1 reference

13 August 2017

Mohamad Navab

16

1 reference

13 August 2017

Judith A Berliner

17

1 reference

13 August 2017

M Luisa Iruela-Arispe

18

1 reference

13 August 2017

language of work or name

English

0 references

publication date

9 November 2015

1 reference

Journal of Experimental Medicine

13 August 2017

1 reference

13 August 2017

212

1 reference

13 August 2017

12

1 reference

13 August 2017

2147-2163

1 reference

describes a project that uses

13 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4647265/fullTextXML

inferred from PubMed Central ID database lookup

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/4647265

inferred from PubMed Central ID database lookup

cites work

Systems Genetics Analysis of Genome-Wide Association Study Reveals Novel Associations Between Key Biological Processes and Coronary Artery Disease

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The role of oxidative stress, antioxidants and vascular inflammation in cardiovascular disease (a review).

30 September 2017

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Human disease modeling reveals integrated transcriptional and epigenetic mechanisms of NOTCH1 haploinsufficiency

30 September 2017

1 reference

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Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells

30 September 2017

1 reference

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Notch signal integration in the vasculature during remodeling

30 September 2017

1 reference

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Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease.

30 September 2017

1 reference

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Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-κB-dependent manner

30 September 2017

1 reference

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Transgenic expression of dominant-active IDOL in liver causes diet-induced hypercholesterolemia and atherosclerosis in mice

30 September 2017

1 reference

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HDL inhibits the effects of oxidized phospholipids on endothelial cell gene expression via multiple mechanisms

30 September 2017

1 reference

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Endothelial Notch activity promotes angiogenesis and osteogenesis in bone

30 September 2017

1 reference

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MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1

30 September 2017

1 reference

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Discovery and refinement of loci associated with lipid levels

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Gene expression analyses of mouse aortic endothelium in response to atherogenic stimuli

30 September 2017

1 reference

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High density lipoproteins and endothelial functions: mechanistic insights and alterations in cardiovascular disease

30 September 2017

1 reference

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Cardioprotective functions of HDLs

30 September 2017

1 reference

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HLA class I antibodies trigger increased adherence of monocytes to endothelial cells by eliciting an increase in endothelial P-selectin and, depending on subclass, by engaging FcγRs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Regulation of signal transduction by HDL.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Identification of CAD candidate genes in GWAS loci and their expression in vascular cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Adaptive immunity in atherogenesis: new insights and therapeutic approaches

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Endothelial deletion of murine Jag1 leads to valve calcification and congenital heart defects associated with Alagille syndrome

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Notch activation induces endothelial cell senescence and pro-inflammatory response: implication of Notch signaling in atherosclerosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Effect of interleukin 1β inhibition in cardiovascular disease

30 September 2017

1 reference

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Role of phospholipid oxidation products in atherosclerosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

The Notch signalling system: recent insights into the complexity of a conserved pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Notch ligand delta-like 4 blockade attenuates atherosclerosis and metabolic disorders

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

The Notch pathway: a crossroad between the life and death of the endothelium

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Network for activation of human endothelial cells by oxidized phospholipids: a critical role of heme oxygenase 1.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Diet-induced aortic valve disease in mice haploinsufficient for the Notch pathway effector RBPJK/CSL

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Notch Signaling in the Vasculature

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Biological, clinical and population relevance of 95 loci for blood lipids

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Variance component model to account for sample structure in genome-wide association studies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Systems genetics analysis of gene-by-environment interactions in human cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

30 September 2017

1 reference

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A comparison of background correction methods for two-colour microarrays

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Identification of inflammatory gene modules based on variations of human endothelial cell responses to oxidized lipids

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

affy--analysis of Affymetrix GeneChip data at the probe level

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Notch4 inhibits endothelial apoptosis via RBP-Jkappa-dependent and -independent pathways

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

TDAG51 Is Induced by Homocysteine, Promotes Detachment-mediated Programmed Cell Death, and Contributes to the Development of Atherosclerosis in Hyperhomocysteinemia

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

CHST1 and CHST2 sulfotransferase expression by vascular endothelial cells regulates shear-resistant leukocyte rolling via L-selectin

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

A high-titer lentiviral production system mediates efficient transduction of differentiated cells including beating cardiac myocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Induction of Jak/STAT signaling by activation of the type 1 TNF receptor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

High-efficiency transformation of mammalian cells by plasmid DNA

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Monocyte migration into the subendothelial space of a coculture of adult human aortic endothelial and smooth muscle cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Oxidized phospholipids are more potent antagonists of lipopolysaccharide than inducers of inflammation.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

gamma-Secretase inhibitor reduces diet-induced atherosclerosis in apolipoprotein E-deficient mice.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Impaired Notch4 activity elicits endothelial cell activation and apoptosis: implication for transplant arteriosclerosis

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Structural identification by mass spectrometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/endothelial interactions and evidence for their presence in vivo

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

smg/rap1/Krev-1 p21s inhibit the signal pathway to the c-fos promoter/enhancer from c-Ki-ras p21 but not from c-raf-1 kinase in NIH3T3 cells

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Microvascular retinal endothelial and pericyte cell apoptosis in vitro: role of hedgehog and Notch signaling.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Inhibition of tumor necrosis factor-alpha reduces atherosclerosis in apolipoprotein E knockout mice

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Determinants of bioactivity of oxidized phospholipids. Specific oxidized fatty acyl groups at the sn-2 position

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Deficient T cell fate specification in mice with an induced inactivation of Notch1.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Quantitation of atherosclerosis in murine models: correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apolipoprotein E-deficient mice.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4647265

Lipoprotein-Derived Lysophosphatidic Acid Promotes Atherosclerosis by Releasing CXCL1 from the Endothelium

22 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26552708

12 December 2020

inferred from PubMed ID database lookup

Regression of atherosclerosis induced by liver-directed gene transfer of apolipoprotein A-I in mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26552708

12 December 2020

inferred from PubMed ID database lookup

Inflammation dysregulates Notch signaling in endothelial cells: implication of Notch2 and Notch4 to endothelial dysfunction

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26552708

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1084/JEM.20150603

1 reference

13 August 2017

1 reference

13 August 2017

PubMed publication ID

26552708

1 reference