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How to save Medicare: the anti-aging remedy
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
3461342
retrieved
13 August 2017
title
How to save Medicare: the anti-aging remedy
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3461342
retrieved
13 August 2017
author
Mikhail Blagosklonny
series ordinal
1
object named as
Mikhail V Blagosklonny
1 reference
stated in
Europe PubMed Central
retrieved
13 August 2017
PMCID
3461342
publication date
1 August 2012
1 reference
stated in
Europe PubMed Central
PMCID
3461342
retrieved
13 August 2017
published in
Aging
1 reference
stated in
Europe PubMed Central
PMCID
3461342
retrieved
13 August 2017
volume
4
1 reference
stated in
Europe PubMed Central
PMCID
3461342
retrieved
13 August 2017
issue
8
1 reference
stated in
Europe PubMed Central
PMCID
3461342
retrieved
13 August 2017
page(s)
547-552
1 reference
stated in
Europe PubMed Central
PMCID
3461342
retrieved
13 August 2017
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Prospective treatment of age-related diseases by slowing down aging
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30 September 2017
Rapamycin slows aging in mice
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PubMed Central
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30 September 2017
Cell cycle arrest is not yet senescence, which is not just cell cycle arrest: terminology for TOR-driven aging
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Health span approximates life span among many supercentenarians: compression of morbidity at the approximate limit of life span
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Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells
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30 September 2017
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30 September 2017
DNA damaging agents and p53 do not cause senescence in quiescent cells, while consecutive re-activation of mTOR is associated with conversion to senescence
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PubMed Central
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30 September 2017
Increasing healthy lifespan by suppressing aging in our lifetime: preliminary proposal
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Metformin for aging and cancer prevention
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30 September 2017
Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice
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30 September 2017
Caloric restriction delays aging-induced cellular phenotypes in rhesus monkey skeletal muscle
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PubMed Central
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30 September 2017
With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging
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PubMed Central
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30 September 2017
Predicting survival and morbidity-free survival to very old age
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30 September 2017
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30 September 2017
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30 September 2017
Rapamycin extends maximal lifespan in cancer-prone mice
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30 September 2017
The genetics of ageing
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PubMed Central
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30 September 2017
Growth and aging: a common molecular mechanism
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PubMed Central
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30 September 2017
Validation of anti-aging drugs by treating age-related diseases
1 reference
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PubMed Central
reference URL
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30 September 2017
Calorie restriction: decelerating mTOR-driven aging from cells to organisms (including humans).
1 reference
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PubMed Central
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30 September 2017
Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster
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30 September 2017
mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells
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30 September 2017
Ribosomal protein S6 kinase 1 signaling regulates mammalian life span
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PubMed Central
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30 September 2017
Caloric restriction delays disease onset and mortality in rhesus monkeys
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461342
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30 September 2017
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
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PubMed Central
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30 September 2017
The TOR pathway comes of age
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PubMed Central
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30 September 2017
Rapamycin decelerates cellular senescence
1 reference
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PubMed Central
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30 September 2017
The scientific basis of caloric restriction leading to longer life.
1 reference
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PubMed Central
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retrieved
30 September 2017
mTORC1-dependent and -independent regulation of stem cell renewal, differentiation, and mobilization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461342
retrieved
30 September 2017
Growth stimulation leads to cellular senescence when the cell cycle is blocked
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461342
retrieved
30 September 2017
Insulin and aging
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461342
retrieved
30 September 2017
Prevention of cancer by inhibiting aging
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461342
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30 September 2017
Aging, stem cells, and mammalian target of rapamycin: a prospect of pharmacologic rejuvenation of aging stem cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461342
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30 September 2017
Visceral adipose tissue modulates mammalian longevity
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461342
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30 September 2017
An anti-aging drug today: from senescence-promoting genes to anti-aging pill
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461342
retrieved
30 September 2017
Targeting mammalian target of rapamycin (mTOR) for health and diseases.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461342
retrieved
30 September 2017
Improvements in glucose tolerance and insulin action induced by increasing energy expenditure or decreasing energy intake: a randomized controlled trial
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461342
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30 September 2017
Aging and immortality: quasi-programmed senescence and its pharmacologic inhibition
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461342
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30 September 2017
Unlocking the secrets of longevity genes
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461342
retrieved
30 September 2017
Morbidity profiles of centenarians: survivors, delayers, and escapers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461342
retrieved
30 September 2017
Genetic pathways that regulate ageing in model organisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461342
retrieved
30 September 2017
Chemoprevention of age-related macular regeneration (AMD) with rapamycin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461342
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29 June 2018
Attenuation of TORC1 signaling delays replicative and oncogenic RAS-induced senescence.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461342
retrieved
29 June 2018
Sirolimus therapy after early cyclosporine withdrawal reduces the risk for cancer in adult renal transplantation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461342
retrieved
29 June 2018
Rapamycin increases lifespan and inhibits spontaneous tumorigenesis in inbred female mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461342
retrieved
22 September 2018
Pharmacological inhibition of phosphoinositide 3 and TOR kinases improves survival of Drosophila melanogaster.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461342
retrieved
22 September 2018
Identification of a highly effective rapamycin schedule that markedly reduces the size, multiplicity, and phenotypic progression of tobacco carcinogen-induced murine lung tumors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461342
retrieved
22 September 2018
Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461342
retrieved
22 September 2018
Hyperinsulinaemia: a prospective risk factor for lethal clinical prostate cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461342
retrieved
22 September 2018
Efficacy and safety of oral sirolimus to inhibit in-stent intimal hyperplasia
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461342
retrieved
22 September 2018
Oral rapamycin to inhibit restenosis after stenting of de novo coronary lesions: the Oral Rapamune to Inhibit Restenosis (ORBIT) study
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461342
retrieved
22 September 2018
Randomized, double-blind, placebo-controlled trial of oral sirolimus for restenosis prevention in patients with in-stent restenosis: the Oral Sirolimus to Inhibit Recurrent In-stent Stenosis (OSIRIS) trial
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461342
retrieved
22 September 2018
Two-year incidence of malignancy in sirolimus-treated renal transplant recipients: results from five multicenter studies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3461342
retrieved
22 September 2018
Rapamycin slows aging in mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22915707
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Centenarians: the older you get, the healthier you have been
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22915707
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Life at the extreme limit: phenotypic characteristics of supercentenarians in Okinawa
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22915707
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.18632/AGING.100479
0 references
PMCID
3461342
1 reference
stated in
Europe PubMed Central
PMCID
3461342
retrieved
13 August 2017
PubMed ID
22915707
1 reference
stated in
Europe PubMed Central
PMCID
3461342
retrieved
13 August 2017
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