(Q36294679)

English

Electrophilic aldehydes generated by sperm metabolism activate mitochondrial reactive oxygen species generation and apoptosis by targeting succinate dehydrogenase.

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22851170%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Electrophilic aldehydes generated by sperm metabolism activate mitochondrial reactive oxygen species generation and apoptosis by targeting succinate dehydrogenase (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22851170%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

apoptotic process

0 references

reactive oxygen species

1 reference

based on heuristic

inferred from title

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22851170%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Geoffry N De Iuliis

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22851170%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

author name string

Sara Whiting

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22851170%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Samantha McClymont

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22851170%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Lisa A Mitchell

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22851170%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Mark A Baker

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22851170%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

language of work or name

0 references

publication date

31 July 2012

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22851170%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22851170%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

287

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22851170%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

39

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22851170%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

33048-33060

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22851170%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Apoptosis in the germ line.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463304

30 September 2017

Redox regulation of human sperm function: from the physiological control of sperm capacitation to the etiology of infertility and DNA damage in the germ line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463304

30 September 2017

On the possible origins of DNA damage in human spermatozoa.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463304

30 September 2017

The spermostatic and microbicidal actions of quinones and maleimides: toward a dual-purpose contraceptive agent.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463304

30 September 2017

Are tests of sperm DNA damage clinically useful? Pros and cons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463304

30 September 2017

Mammalian sperm metabolism: oxygen and sugar, friend and foe.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463304

30 September 2017

4-hydroxynonenal (4-HNE) has been widely accepted as an inducer of oxidative stress. Is this the whole truth about it or can 4-HNE also exert protective effects?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463304

30 September 2017

Decreased complex II respiration and HNE-modified SDH subunit in diabetic heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463304

30 September 2017

Regulation of sperm function by reactive oxygen species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463304

30 September 2017

VDAC1 is a transplasma membrane NADH-ferricyanide reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463304

30 September 2017

4-Hydroxy-2-nonenal: a product and mediator of oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463304

30 September 2017

Mechanism of superoxide and hydrogen peroxide formation by fumarate reductase, succinate dehydrogenase, and aspartate oxidase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463304

30 September 2017

Reactive oxygen species generation and human spermatozoa: the balance of benefit and risk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463304

30 September 2017

Population study of causes, treatment, and outcome of infertility.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463304

30 September 2017

Inactivation of the 2-oxo acid dehydrogenase complexes upon generation of intrinsic radical species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463304

29 June 2018

Cellular basis of defective sperm function and its association with the genesis of reactive oxygen species by human spermatozoa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463304

29 June 2018

Hydrogen peroxide is involved in hamster sperm capacitation in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463304

29 June 2018

Prospective analysis of sperm-oocyte fusion and reactive oxygen species generation as criteria for the diagnosis of infertility.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463304

29 June 2018

Mitochondrial metabolism of pyruvate in bovine spermatozoa.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463304

29 June 2018

Peroxidative Breakdown of Phospholipids in Human Spermatozoa, Spermicidal Properties of Fatty Acid Peroxides, and Protective Action of Seminal Plasma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463304

29 June 2018

Generation of reactive oxygen species, lipid peroxidation, and human sperm function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.366690

21 January 2018

DNA damage in human spermatozoa is highly correlated with the efficiency of chromatin remodeling and the formation of 8-hydroxy-2'-deoxyguanosine, a marker of oxidative stress.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.366690

21 January 2018

Significance of mitochondrial reactive oxygen species in the generation of oxidative stress in spermatozoa

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.366690

21 January 2018

Effects of H(2)O(2) exposure on human sperm motility parameters, reactive oxygen species levels and nitric oxide levels

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.366690

21 January 2018

Multiple forms of redox activity in populations of human spermatozoa.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.366690

21 January 2018

Phosphoinositide 3-kinase signalling pathway involvement in a truncated apoptotic cascade associated with motility loss and oxidative DNA damage in human spermatozoa.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.366690

21 January 2018

Electrophilicity Index

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.366690

21 January 2018

Kinetic glutathione chemoassay to quantify thiol reactivity of organic electrophiles--application to alpha,beta-unsaturated ketones, acrylates, and propiolates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.366690

21 January 2018

Hamster sperm capacitation: role of pyruvate dehydrogenase A and dihydrolipoamide dehydrogenase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.366690

21 January 2018

4-Hydroxy-2(E)-nonenal inhibits CNS mitochondrial respiration at multiple sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.366690

21 January 2018

Stimulation of mitochondrial reactive oxygen species production by unesterified, unsaturated fatty acids in defective human spermatozoa.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.366690

21 January 2018

Interaction of electrophilic lipid oxidation products with mitochondria in endothelial cells and formation of reactive oxygen species

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.366690

21 January 2018

Role of 4-hydroxynonenal in modification of cytochrome c oxidase in ischemia/reperfused rat heart

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.366690

21 January 2018

Succinate is the controller of O2-/H2O2 release at mitochondrial complex I : negative modulation by malate, positive by cyanide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.366690

21 January 2018

Integrity of mitochondrial membrane potential reflects human sperm quality

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.366690

21 January 2018

A novel signal transduction cascade in capacitating human spermatozoa characterised by a redox-regulated, cAMP-mediated induction of tyrosine phosphorylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3463304

22 September 2018

The TUNEL assay consistently underestimates DNA damage in human spermatozoa and is influenced by DNA compaction and cell vitality: development of an improved methodology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.366690

21 January 2018

Formation of Hydrogen Peroxide by Spermatozoa and Its Inhibitory Effect on Respiration

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.366690

21 January 2018

Generation of superoxide anion by succinate-cytochrome c reductase from bovine heart mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/22851170

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inactivation of succinate dehydrogenase by bromopyruvate

1 reference

https://pubmed.ncbi.nlm.nih.gov/22851170

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on Escherichia coli pyruvate dehydrogenase complex. I. Effect of bromopyruvate on the catalytic activities of the complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/22851170

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EAU guidelines on male infertility

1 reference

https://pubmed.ncbi.nlm.nih.gov/22851170

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spontaneous lipid peroxidation and production of hydrogen peroxide and superoxide in human spermatozoa. Superoxide dismutase as major enzyme protectant against oxygen toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22851170

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human sperm hyperactivation and capacitation as parts of an oxidative process

1 reference

https://pubmed.ncbi.nlm.nih.gov/22851170

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.366690

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22851170%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22851170%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22851170%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q36294679&oldid=1414493242"