(Q36301424)

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(31) P and (1) H MRS of DB-1 melanoma xenografts: lonidamine selectively decreases tumor intracellular pH and energy status and sensitizes tumors to melphalan

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22745015%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

(31) P and (1) H MRS of DB-1 melanoma xenografts: lonidamine selectively decreases tumor intracellular pH and energy status and sensitizes tumors to melphalan (English)

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6 February 2020

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5

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6 February 2020

Seung-Cheol Lee

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Seung-Cheol Lee

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6 February 2020

6

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Stephen Pickup

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6 February 2020

Jerry D Glickson

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Jerry D Glickson

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6 February 2020

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Kavindra Nath

1

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6 February 2020

David S Nelson

2

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6 February 2020

Andrew M Ho

3

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6 February 2020

Rong Zhou

7

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6 February 2020

Daniel F Heitjan

8

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6 February 2020

Dennis B Leeper

9

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6 February 2020

publication date

29 June 2012

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6 February 2020

NMR in Biomedicine

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6 February 2020

26

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6 February 2020

1

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6 February 2020

98-105

1 reference

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PMC publication ID

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6 February 2020

Ipilimumab in treatment-naive and previously treated patients with metastatic melanoma: retrospective analysis of efficacy and safety data from a phase II trial

1 reference

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30 September 2017

Current trends in autologous stem-cell transplantation for myeloma in the era of novel therapies

1 reference

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30 September 2017

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

1 reference

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30 September 2017

Down-regulation of P-glycoprotein expression by sustained intracellular acidification in K562/Dox cells

1 reference

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30 September 2017

Lactate imaging with Hadamard-encoded slice-selective multiple quantum coherence chemical-shift imaging

1 reference

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30 September 2017

Cancer statistics, 2006

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465621

30 September 2017

Reduction of intracellular pH as a strategy to enhance the pH-dependent cytotoxic effects of melphalan for human breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465621

30 September 2017

Lonidamine: efficacy and safety in clinical trials for the treatment of solid tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465621

30 September 2017

Noninvasive real-time monitoring of intracellular cancer cell metabolism and response to lonidamine treatment using diffusion weighted proton magnetic resonance spectroscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465621

30 September 2017

Potentiation of anti-cancer drug activity at low intratumoral pH induced by the mitochondrial inhibitor m-iodobenzylguanidine (MIBG) and its analogue benzylguanidine (BG).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465621

30 September 2017

Intracellular pH and the control of multidrug resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465621

30 September 2017

A phase II clinical and pharmacokinetic study of Lonidamine in patients with advanced breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465621

30 September 2017

The Warburg hypothesis fifty years later

1 reference

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30 September 2017

L-lactate transport in Ehrlich ascites-tumour cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465621

30 September 2017

The cytotoxicity of melphalan and its relationship to pH, hypoxia and drug uptake.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465621

30 September 2017

On mathematical modeling of critical variables in cancer treatment (goals: better understanding of the past and better planning in the future).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465621

30 September 2017

The role of low intracellular or extracellular pH in sensitization to hyperthermic radiosensitization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465621

29 June 2018

The role of intracellular pH and its variance in low pH sensitization of killing by hyperthermia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465621

29 June 2018

Modification of intracellular pH and thermosensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465621

29 June 2018

Phase I and pharmacokinetic study of bendamustine hydrochloride in relapsed or refractory indolent B-cell non-Hodgkin lymphoma and mantle cell lymphoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465621

22 September 2018

The development of lonidamine for benign prostatic hyperplasia and other indications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465621

22 September 2018

Metaiodobenzylguanidine and hyperglycemia augment tumor response to isolated limb perfusion in a rodent model of human melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465621

22 September 2018

Regulation of intracellular pH in human melanoma: potential therapeutic implications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465621

22 September 2018

Enhancement of hyperglycemia-induced acidification of human melanoma xenografts with inhibitors of respiration and ion transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465621

22 September 2018

Mathematical modelling of tumour acidity: regulation of intracellular pH.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465621

22 September 2018

Mechanism of action of lonidamine in the 9L brain tumor model involves inhibition of lactate efflux and intracellular acidification.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465621

22 September 2018

31P-MRS measurements of extracellular pH of tumors using 3-aminopropylphosphonate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465621

22 September 2018

The effect of blood flow modification on intra- and extracellular pH measured by 31P magnetic resonance spectroscopy in murine tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465621

22 September 2018

Changes of energy metabolism in the germ cells and Ehrlich ascites tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22745015

12 December 2020

based on heuristic

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Hydrogen ion-mediated enhancement of cytotoxicity of bis-chloroethylating drugs in rat mammary carcinoma cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/22745015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potentiation of DNA-adduct formation and cytotoxicity of platinum-containing drugs by low pH

1 reference

https://pubmed.ncbi.nlm.nih.gov/22745015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular acidification of human melanoma xenografts by the respiratory inhibitor m-iodobenzylguanidine plus hyperglycemia: a 31P magnetic resonance spectroscopy study

1 reference

https://pubmed.ncbi.nlm.nih.gov/22745015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of lonidamine on the energy metabolism of Ehrlich ascites tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22745015

12 December 2020

based on heuristic

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Mechanism of action of the antineoplastic drug lonidamine: 31P and 13C nuclear magnetic resonance studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/22745015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo imaging of extracellular pH using1H MRSI

1 reference

https://pubmed.ncbi.nlm.nih.gov/22745015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An assessment of31P MRS as a method of measuring pH in rat tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/22745015

12 December 2020

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22745015

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based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22745015

12 December 2020

based on heuristic

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Metabolic response of AH13r rat tumours to cyclophosphamide as monitored by pO2 and pH semi-microelectrodes

1 reference

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Growth and metastasis of fresh human melanoma tissue in mice with severe combined immunodeficiency

1 reference

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12 December 2020

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Action of the antitumor and antispermatogenic agent lonidamine on electron transport in ehrlich ascites tumor mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/22745015

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Nigericin enhances mafosfamide cytotoxicity at low extracellular pH

1 reference

https://pubmed.ncbi.nlm.nih.gov/22745015

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/NBM.2824

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Europe PubMed Central

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6 February 2020

PMC publication ID

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6 February 2020

PubMed publication ID

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Europe PubMed Central

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6 February 2020

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