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Evidence-based support for the use of proton pump inhibitors in cancer therapy
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
4657328
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26597250%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
editorial
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title
Evidence-based support for the use of proton pump inhibitors in cancer therapy
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
4657328
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26597250%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
author
Stefano Fais
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4657328
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26597250%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
author name string
Stefano Fais
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4657328
retrieved
13 August 2017
publication date
24 November 2015
1 reference
stated in
Europe PubMed Central
PMC publication ID
4657328
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26597250%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
published in
Journal of Translational Medicine
1 reference
stated in
Europe PubMed Central
PMC publication ID
4657328
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26597250%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
volume
13
1 reference
stated in
Europe PubMed Central
PMC publication ID
4657328
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26597250%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
page(s)
368
1 reference
stated in
Europe PubMed Central
PMC publication ID
4657328
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26597250%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
exact match
https://scigraph.springernature.com/pub.10.1186/s12967-015-0735-2
0 references
cites work
Microenvironment acidity as a major determinant of tumor chemoresistance: Proton pump inhibitors (PPIs) as a novel therapeutic approach.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Intermittent high dose proton pump inhibitor enhances the antitumor effects of chemotherapy in metastatic breast cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Proton pump inhibitors while belonging to the same family of generic drugs show different anti-tumor effect.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Global cancer statistics, 2012
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Proton pump inhibitors and histamine 2 blockers are associated with improved overall survival in patients with head and neck squamous carcinoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Proton channels and exchangers in cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Microenvironmental acidosis in carcinogenesis and metastases: new strategies in prevention and therapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
High dose lansoprazole combined with metronomic chemotherapy: a phase I/II study in companion animals with spontaneously occurring tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Paradoxically augmented anti-tumorigenic action of proton pump inhibitor and GastrininAPCMin/+ intestinal polyposis model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
V-ATPase inhibition regulates anoikis resistance and metastasis of cancer cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Dysregulated pH in Tumor Microenvironment Checkmates Cancer Therapy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Atp6v1c1 may regulate filament actin arrangement in breast cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
V-ATPase as an effective therapeutic target for sarcomas
2 references
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1186%2FS12967-015-0735-2
retrieved
21 January 2018
Cariporide and other new and powerful NHE1 inhibitors as potentially selective anticancer drugs--an integral molecular/biochemical/metabolic/clinical approach after one hundred years of cancer research
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Proton pump inhibitor chemosensitization in human osteosarcoma: from the bench to the patients' bed
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Silencing of atp6v1c1 prevents breast cancer growth and bone metastasis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
V-ATPase inhibition overcomes trastuzumab resistance in breast cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
The expression of V-ATPase is associated with drug resistance and pathology of non-small-cell lung cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
V-ATPase is a candidate therapeutic target for Ewing sarcoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
The role of proton dynamics in the development and maintenance of multidrug resistance in cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
ABCG2/V-ATPase was associated with the drug resistance and tumor metastasis of esophageal squamous cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Mode of cell death induction by pharmacological vacuolar H+-ATPase (V-ATPase) inhibition
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Epigenetic mechanisms in tumorigenesis, tumor cell heterogeneity and drug resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Lansoprazole as a rescue agent in chemoresistant tumors: a phase I/II study in companion animals with spontaneously occurring tumors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Drug resistance and cellular adaptation to tumor acidic pH microenvironment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
The vacuolar-ATPase modulates matrix metalloproteinase isoforms in human pancreatic cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Multidrug resistance in oral squamous cell carcinoma: The role of vacuolar ATPases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
pH-dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Proton pump inhibitors: actions and reactions.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Role of V-ATPases in solid tumors: importance of the subunit C (Review).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Small interfering RNA targeting the subunit ATP6L of proton pump V-ATPase overcomes chemoresistance of breast cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Targeting vacuolar H+-ATPases as a new strategy against cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Vacuolar ATPases: rotary proton pumps in physiology and pathophysiology
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Drug resistance and the solid tumor microenvironment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
The Warburg effect and its cancer therapeutic implications
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Proton pump inhibitors induce apoptosis of human B-cell tumors through a caspase-independent mechanism involving reactive oxygen species.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Tumor acidity, chemoresistance and proton pump inhibitors.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Vacuolar H+-ATPase in human breast cancer cells with distinct metastatic potential: distribution and functional activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Cellular pH regulators: potentially promising molecular targets for cancer chemotherapy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
On the Origin of Cancer Cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Biologic considerations for drug targeting in cancer patients
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
30 September 2017
Immunohistochemical localization of C1 subunit of V-ATPase (ATPase C1) in oral squamous cell cancer and normal oral mucosa
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
29 June 2018
Proton dynamics in cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
29 June 2018
Regulation of endothelial signaling and migration by v-ATPase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
22 September 2018
Expression and functional role of vacuolar H(+)-ATPase in human hepatocellular carcinoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
22 September 2018
Modulation of microenvironment acidity reverses anergy in human and murine tumor-infiltrating T lymphocytes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
22 September 2018
V-ATPase engagement in autophagic processes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
22 September 2018
Measurement of ATP6V1C1 expression in brush cytology samples as a diagnostic and prognostic marker in oral squamous cell carcinoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
22 September 2018
A change of strategy in the war on cancer.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657328
retrieved
22 September 2018
Lansoprazole induces sensitivity to suboptimal doses of paclitaxel in human melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1186%2FS12967-015-0735-2
retrieved
21 January 2018
pH and drug resistance. I. functional expression of plasmalemmal V-type H+-ATPase in drug-resistant human breast carcinoma cell lines
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26597250
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
pH and drug resistance. II. turnover of acidic vesicles and resistance to weakly basic chemotherapeutic drugs
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26597250
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Tumor pH controls the in vivo efficacy of weak acid and base chemotherapeutics
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26597250
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1186/S12967-015-0735-2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4657328
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26597250%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
PMC publication ID
4657328
1 reference
stated in
Europe PubMed Central
PMC publication ID
4657328
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26597250%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
PubMed publication ID
26597250
1 reference
stated in
Europe PubMed Central
PMC publication ID
4657328
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26597250%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 March 2020
ResearchGate publication ID
284563307
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